NCT02 - Moligand™, ≥99% , CAS No.790245-61-3

CAS: 790245-61-3 Cat. No.: N648209 분자식: C₁₇H₁₆N₂O₂S 분자량: 312.39 EC 번호: 840-752-4 PubChem CID: 2501755

등급 & 순도 Moligand™, ≥99%

Synonyms

2-(6,7-Dihydro-5H-indeno[5,6-b]furan-3-yl)-N-(5-methylthiazol-2-yl)acetamide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

NCT02 is a cyclin K degrader. NCT02 induces ubiquitination of cyclin K (CCNK) and proteasomal degradation of CCNK and its complex partner CDK12. NCT02 has the potential for the research of metastatic colorectal cancer (CRC).

Form:Solid

사양

동의어

2-(6,7-Dihydro-5H-indeno[5,6-b]furan-3-yl)-N-(5-methylthiazol-2-yl)acetamide

사양 및 순도

Moligand™, ≥99%

생화학 및 생리적 메커니즘

NCT02 is a cyclin K degrader. NCT02 induces ubiquitination of cyclin K (CCNK) and proteasomal degradation of CCNK and its complex partner CDK12 . NCT02 has the potential for the research of metastatic colorectal cancer (CRC).

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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등급

Moligand™

순수함

≥99%

이름과 식별자

이성체 SMILES

CC1=CN=C(S1)NC(=O)CC2=COC3=C2C=C4CCCC4=C3

PubChem CID

2501755

분자량

312.39

화학 및 물리적 특성

• 용해성: DMSO : 50 mg/mL (160.06 mM; Need ultrasonic)
• 분자량: 312.400 g/mol
• XLogP3: 3.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 312.093 Da
• Monoisotopic Mass: 312.093 Da
• Topological Polar Surface Area: 83.400 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 433.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1