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NHC-diphosphate - ≥98% , CAS No.39023-73-9
주문 가능
GRADE & PURITY ≥98%
Storage
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
개요
NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) ( HY-125033 ) as a diphosphate form. NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent. NHC effectively inhibits the replication of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV).
In Vitro
Huh-7 cells are incubated with (10-50 μM; 4 h) NHC or a McGuigan phosphoramidate prodrug of NHC. Intracellular levels of the parental compounds and phosphorylated metabolites are measured using LC-MS/MS. Small amounts of NHC-monophosphate (MP) and NHC-diphosphate (DP; HY-135867D) can be observed, while NHC-triphosphate remains the most abundant metabolite.. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Specifications
사양 및 순도
≥98%
생화학 및 생리적 메커니즘
NHC-diphosphate is an active phosphorylatedxa0intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) ( HY-125033 ) as a diphosphate form. NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent . NHC effectively inhibits the re
보관 조건
Protected from light,Store at -20°C,Argon charged
배송
Ice chest + Ice pads
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작업 유형
INHIBITOR
순수함
≥98%
이름과 식별자
| 분자량 | 419.18 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
| 용해성 | H2O : 160 mg/mL (381.70 mM; Need ultrasonic) |
|---|
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