Name: Nomifensine - 10mM in DMSO , Monoamine transporter inhibitor, CAS No.32795-47-4, Monoamine transporter inhibitor
SKU: N580464
Availability: InStock

Nomifensine - 10mM in DMSO , Monoamine transporter inhibitor, CAS No.32795-47-4, Monoamine transporter inhibitor

CAS: 32795-47-4 Cat. No.: N580464 분자식: C₁₆H₁₈N₂ • C₄H₄O₄ 분자량: 354.40 EC 번호: 251-223-7

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Nomifensine - 10mM in DMSO CAS No(32795-47-4) by Aladdin Scientific

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주문 가능

GRADE & PURITY 10mM in DMSO

Synonyms

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요 Specifications 이름과 식별자 Documentation Advanced Data Taxonomic Classification 3D 구조 관련 대상(인간) 관련 대상(비인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 솔루션 계산기 리뷰

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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Biochemical mechanism:

Nomifensine maleate is a selective dopamine uptake inhibitor interacting with the dopamine transporter, at a site different from that of cocaine; antidepressant. Nomifensine serves as an antidepressant and is known to cause frequent hemolytic anemia. The aniline group in this compound results in blood and liver toxicities.

Specifications

동의어

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

Potent inhibitor of noradrenalin and dopamine uptake (Kivalues are 4.7, 26 and 4000 nM for inhibition of noradrenalin, dopamine and 5-HT uptake respectively, in rat brain). Increases central dopamine levels in rats following systemic administration. Displ

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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작업 유형

INHIBITOR

작동 메커니즘

Monoamine transporter inhibitor

이름과 식별자

Pubchem Sid	528775706
정식 스마일	CN1CC(C2=C(C1)C(=CC=C2)N)C3=CC=CC=C3.C(=CC(=O)O)C(=O)O
IUPAC Name	(Z)-but-2-enedioic acid;2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine
InChIKey	GEOCVSMCLVIOEV-BTJKTKAUSA-N
INCHI	1S/C16H18N2.C4H4O4/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18;5-3(6)1-2-4(7)8/h2-9,14H,10-11,17H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
이성체 SMILES	CN1CC(C2=C(C1)C(=CC=C2)N)C3=CC=CC=C3.C(=C\C(=O)O)\C(=O)O
WGK 독일	3
RTECS	NX4912800
분자량	354.40
Reaxy-Rn	23011294
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23011294&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - 분류 Tetrahydroisoquinolines
    - Subclass 4-phenyltetrahydroisoquinolines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
분류	Tetrahydroisoquinolines
Subclass	4-phenyltetrahydroisoquinolines
Intermediate Tree Nodes	Not available
Direct Parent	4-phenyltetrahydroisoquinolines
Alternative Parents	Aminoquinolines and derivatives Aralkylamines Unsaturated fatty acids Dicarboxylic acids and derivatives Benzene and substituted derivatives Trialkylamines Carboxylic acids Azacyclic compounds Primary amines Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Not available
Substituents	4-phenyltetrahydroisoquinoline - Aminoquinoline - Aralkylamine - Monocyclic benzene moiety - Dicarboxylic acid or derivatives - Unsaturated fatty acid - Benzenoid - Fatty acyl - Fatty acid - Tertiary amine - Tertiary aliphatic amine - Carboxylic acid - Carboxylic acid derivative - Azacycle - Amine - Organic nitrogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Organic oxide - Carbonyl group - Organopnictogen compound - Organic oxygen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
설명	This compound belongs to the class of organic compounds known as 4-phenyltetrahydroisoquinolines. These are compounds containing a phenyl group attached to the C4-atom of a tetrahydroisoquinoline moiety.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D 구조

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리뷰

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용해성	Solvent:DMSO, Max Conc. mg/mL: 35.44, Max Conc. mM: 100
감도	Moisture sensitive
분자량	354.400 g/mol
XLogP3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	354.158 Da
Monoisotopic Mass	354.158 Da
Topological Polar Surface Area	104.000 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	391.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	2