NS 383 - Moligand™ , Channel blocker of ASIC1;Channel blocker of ASIC3, CAS No.309711-59-9, Channel blocker of ASIC1;Channel blocker of ASIC3

CAS: 309711-59-9 Cat. No.: N288698 분자식: C₁₉H₁₉N₃O₂ 분자량: 321.37 PubChem CID: 135418391

GRADE & PURITY Moligand™

Synonyms

8-Ethyl-6,7,8,9-tetrahydro-5-phenyl-1H-pyrrolo[3,2-h]isoquinoline-2,3-dione-3-oxime

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

동의어

8-Ethyl-6,7,8,9-tetrahydro-5-phenyl-1H-pyrrolo[3,2-h]isoquinoline-2,3-dione-3-oxime

사양 및 순도

Moligand™

생화학 및 생리적 메커니즘

ASIC blocker (IC50values are 0.44, 2.1 μM and no effect at rat ASIC1a, ASIC3 and ASIC2a, respectively: IC50value = 0.12 μM at human ASIC1a with no effect at ASIC2a or ASIC3). Inhibition was also observed at heteromeric ASIC channels (IC50values are 0.79,

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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등급

Moligand™

작업 유형

CHANNEL BLOCKER

작동 메커니즘

Channel blocker of ASIC1;Channel blocker of ASIC3

이름과 식별자

• 정식 스마일: CCN1CCC2=C(C=C3C(=C2C1)NC(=C3N=O)O)C4=CC=CC=C4
• IUPAC Name: 8-ethyl-3-nitroso-5-phenyl-1,6,7,9-tetrahydropyrrolo[3,2-h]isoquinolin-2-ol
• InChIKey: OZVZKENYKWSYBC-UHFFFAOYSA-N
• INCHI: 1S/C19H19N3O2/c1-2-22-9-8-13-14(12-6-4-3-5-7-12)10-15-17(16(13)11-22)20-19(23)18(15)21-24/h3-7,10,20,23H,2,8-9,11H2,1H3
• PubChem CID: 135418391
• 분자량: 321.37

관련 대상(인간)

ASIC3 Tchem Acid-sensing ion channel 3 (0 Activities)

Discover Target: ASIC3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ASIC1 Tchem Acid-sensing ion channel 1 (0 Activities)

Discover Target: ASIC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

화학 및 물리적 특성

• 용해성: Solvent:DMSO, Max Conc. mg/mL: 1.61, Max Conc. mM: 5

자주 묻는 질문

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 309711-59-9, the molecular formula is C??H??N?O?, and the molecular weight is 321.37 g/mol. InChIKey OZVZKENYKWSYBC-UHFFFAOYSA-N.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.