ONC206 - 10mM in DMSO , CAS No.1638178-87-6

CAS: 1638178-87-6 Cat. No.: O422018 분자식: C23H22F2N4O 분자량: 408.44
주문 가능
등급 & 순도 10mM in DMSO
Synonyms
Onc 206 | AKOS040742338 | 11-benzyl-7-[(2,4-difluorophenyl)methyl]-2,5,7,11-tetrazatricyclo[7.4.0.02,6]trideca-1(9),5-dien-8-one | ONC 206 [WHO-DD] | s6853 | HY-135147 | 1638178-87-6 | ONC-206, ONC206 Powder | OW6LM47PNK | 4-((2,4-Difluorophenyl)methyl)-2
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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수량
1ml
O422018-1ml
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이 등급을 선택하는 이유

10mM in DMSO 최소한의 기준선 간섭이 필요한 민감한 크로마토그래피 및 분석 워크플로우용.

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보관 및 배송

Store at -80°C Dry ice packs + Cold packs 출고. 정확한 사양은 로트별 COA를 확인하세요.

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품질 문서

SDS, COA, 데이터시트, 사양서를 다운로드할 수 있습니다. 로트별 COA는 로트 번호 조회를 통해 확인할 수 있습니다.

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문헌적 근거

크로마토그래피, 유기 합성 및 교차 커플링 반응 분야의 동료 심사 논문 0편에서 인용되었습니다.

개요

Product Introduction

ONC206 is an analogue of TRAIL inducer ONC201 and is a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations. ONC206 also has broad-spectrum anti-tumor activity.

사양

동의어
Onc 206 | AKOS040742338 | 11-benzyl-7-[(2,4-difluorophenyl)methyl]-2,5,7,11-tetrazatricyclo[7.4.0.02,6]trideca-1(9),5-dien-8-one | ONC 206 [WHO-DD] | s6853 | HY-135147 | 1638178-87-6 | ONC-206, ONC206 Powder | OW6LM47PNK | 4-((2,4-Difluorophenyl)methyl)-2
사양 및 순도
10mM in DMSO
생화학 및 생리적 메커니즘
ONC206 (Oncoceutics) is an imipiridone with nanomolar potency and analogue of ONC201, a selective dopamine receptor D2 (DRD2) antagonist currently being investigated in phase II clinical trials for serous endometrial cancer (SEC). ONC206 inhibited cellul
보관 조건
Store at -80°C
배송
Dry ice packs + Cold packs
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
이름과 식별자
Pubchem Sid
정식 스마일
C1CN(CC2=C1N3CCN=C3N(C2=O)CC4=C(C=C(C=C4)F)F)CC5=CC=CC=C5
IUPAC Name
11-benzyl-7-[(2,4-difluorophenyl)methyl]-2,5,7,11-tetrazatricyclo[7.4.0.02,6]trideca-1(9),5-dien-8-one
InChIKey
ITMGVSSHWMTJRR-UHFFFAOYSA-N
INCHI
1S/C23H22F2N4O/c24-18-7-6-17(20(25)12-18)14-29-22(30)19-15-27(13-16-4-2-1-3-5-16)10-8-21(19)28-11-9-26-23(28)29/h1-7,12H,8-11,13-15H2
이성체 SMILES
C1CN(CC2=C1N3CCN=C3N(C2=O)CC4=C(C=C(C=C4)F)F)CC5=CC=CC=C5
분자량
408.44
Reaxy-Rn
30398993
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30398993&ln=

문서

📋 안전 데이터 시트(SDS)

위험성, 취급, 보관 및 규제 준수를 포괄하는 종합 문서.

<<<<<<< HEAD SDS 다운로드 → ======= SDS 다운로드 → >>>>>>> release248-p3

✅ 분석 성적서(COA)

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📊 데이터시트

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고급 데이터

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
분류Imidazopyrimidines
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentImidazopyrimidines
Alternative Parents Phenylmethylamines  Benzylamines  Fluorobenzenes  Aralkylamines  Hydropyrimidines  Aryl fluorides  Vinylogous amides  Imidazolines  Trialkylamines  Guanidines  Amino acids and derivatives  Propargyl-type 1,3-dipolar organic compounds  Enamines  Carboximidamides  Azacyclic compounds  Organopnictogen compounds  Organofluorides  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Imidazopyrimidine - Phenylmethylamine - Benzylamine - Aralkylamine - Halobenzene - Fluorobenzene - Benzenoid - 1,2,3,4-tetrahydropyrimidine - Hydropyrimidine - Monocyclic benzene moiety - Aryl halide - Aryl fluoride - Vinylogous amide - 2-imidazoline - Tertiary aliphatic amine - Tertiary amine - Guanidine - Amino acid or derivatives - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Enamine - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Carbonyl group - Amine - Aromatic heteropolycyclic compound
설명This compound belongs to the class of organic compounds known as imidazopyrimidines. These are organic polycyclic compounds containing an imidazole ring fused to a pyrimidine ring. Imidazole is 5-membered ring consisting of three carbon atoms, and two nitrogen centers at the 1- and 3-positions. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions.
External Descriptors Not available
3D 구조
상호 작용 화학 구조 모델





인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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1 results found

Lot NumberCertificate Type날짜항목
K2411565K2411565Certificate of AnalysisSep 01, 2026 O422018
화학 및 물리적 특성
분자량408.400 g/mol
XLogP32.200
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass408.176 Da
Monoisotopic Mass408.176 Da
Topological Polar Surface Area39.200 Ų
Heavy Atom Count30
Formal Charge0
Complexity733.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
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