PARPi-FL - ≥98% , CAS No.1380359-84-1

CAS: 1380359-84-1 Cat. No.: P286654 분자식: C₃₄H₃₂BF₃N₆O₃ 분자량: 640.46 PubChem CID: 70697686

등급 & 순도 ≥98%

Synonyms

Boron, (4-((3-((4-(3-(5-((3,5-dimethyl-2H-pyrrol-2-ylidene-kappaN)methyl)-1H-pyrrol-2-yl-kappaN)-1-oxopropyl)-1-piperazinyl)carbonyl)-4-fluorophenyl)methyl)-1(2H)-phthalazinonato)difluoro-, (T-4)- | 1380359-84-1 | 4-[[3-[4-[3-(2,2-difluoro-10,12-dimethyl-

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

사양

동의어

Boron, (4-((3-((4-(3-(5-((3,5-dimethyl-2H-pyrrol-2-ylidene-kappaN)methyl)-1H-pyrrol-2-yl-kappaN)-1-oxopropyl)-1-piperazinyl)carbonyl)-4-fluorophenyl)methyl)-1(2H)-phthalazinonato)difluoro-, (T-4)- | 1380359-84-1 | 4-[[3-[4-[3-(2,2-difluoro-10,12-dimethyl-

사양 및 순도

≥98%

생화학 및 생리적 메커니즘

Fluorescent potent PARP inhibitor (IC50= 12 nM). Composed of a PARP inhibitor conjugated toBDY FL, SE. Colocalizes with PARP immunostaining in multiple cancer cell linesin vivoand accumulates in tumor cells and tumor associated macrophages. Enables high t

보관 조건

Protected from light,Store at -20°C

배송

Ice chest + Ice pads

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작업 유형

INHIBITOR

순수함

≥98%

이름과 식별자

정식 스마일

[B-]1(N2C(=CC(=C2C=C3[N+]1=C(C=C3)CCC(=O)N4CCN(CC4)C(=O)C5=C(C=CC(=C5)CC6=NNC(=O)C7=CC=CC=C76)F)C)C)(F)F

IUPAC Name

4-[[3-[4-[3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)propanoyl]piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one

InChIKey

IGUTVNUEFKPBGK-UHFFFAOYSA-N

INCHI

1S/C34H32BF3N6O3/c1-21-17-22(2)43-31(21)20-25-9-8-24(44(25)35(43,37)38)10-12-32(45)41-13-15-42(16-14-41)34(47)28-18-23(7-11-29(28)36)19-30-26-5-3-4-6-27(26)33(46)40-39-30/h3-9,11,17-18,20H,10,12-16,19H2,1-2H3,(H,40,46)

이성체 SMILES

[B-]1(N2C(=CC(=C2C=C3[N+]1=C(C=C3)CCC(=O)N4CCN(CC4)C(=O)C5=C(C=CC(=C5)CC6=NNC(=O)C7=CC=CC=C76)F)C)C)(F)F

PubChem CID

70697686

분자량

640.46

화학 및 물리적 특성

• 용해성: Solvent:DMSO, Max Conc. mg/mL: 6.4, Max Conc. mM: 10
• 감도: light sensitive

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1380359-84-1, the molecular formula is C??H??BF?N?O?, and the molecular weight is 640.46 g/mol. InChIKey IGUTVNUEFKPBGK-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.