PDE1-IN-2 - ≥98% , CAS No.1904611-63-7

CAS: 1904611-63-7 Cat. No.: P650849 분자식: C₁₆H₂₁BrN₄O₂ 분자량: 381.27 PubChem CID: 121273157

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

PDE1-IN-2 is a PDE1 inhibitor extracted from patent WO2016/55618 A1, example 31. PDE1-IN-2 has IC 50 values of 6 nM, 140 nM and 164 nM for PDE1C, PDE1B and PDE1A, respectvely. PDE1-IN-2 is developed for the research of neurodegenerative disorders and psychiatric disorders

In Vitro

PDE1 enzymes are expressed in the central nervous system (CNS), making this gene family an attractive source of new targets for the treatment of psychiatric and neurodegenerative disorders. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:PDE1A 164 nM (IC 50 ) PDE1B 140 nM (IC 50 ) PDE1C 6 nM (IC 50 )

Specifications

사양 및 순도

≥98%

생화학 및 생리적 메커니즘

PDE1-IN-2 is a PDE1 inhibitor extracted from patent WO2016/55618 A1, example 31. PDE1-IN-2 has IC 50 values of 6 nM, 140 nM and 164 nM for PDE1C, PDE1B and PDE1A, respectvely. PDE1-IN-2 is developed for the research of neurodegenerative disorders and psyc

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

작업 유형

INHIBITOR

순수함

≥98%

이름과 식별자

• 정식 스마일: C1CCC(C1)CN2C(=CN3C(=NN=C3C2=O)C4CCOCC4)Br
• IUPAC Name: 6-bromo-7-(cyclopentylmethyl)-3-(oxan-4-yl)-[1,2,4]triazolo[4,3-a]pyrazin-8-one
• InChIKey: UDLAXUPVISWZSI-UHFFFAOYSA-N
• INCHI: 1S/C16H21BrN4O2/c17-13-10-21-14(12-5-7-23-8-6-12)18-19-15(21)16(22)20(13)9-11-3-1-2-4-11/h10-12H,1-9H2
• PubChem CID: 121273157
• 분자량: 381.27

화학 및 물리적 특성

• 용해성: DMSO : 25 mg/mL (65.57 mM; Need ultrasonic)
• 분자량: 381.270 g/mol
• XLogP3: 2.300
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 380.085 Da
• Monoisotopic Mass: 380.085 Da
• Topological Polar Surface Area: 60.300 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 488.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1904611-63-7, the molecular formula is C16H21BrN4O2, and the molecular weight is 381.27 g/mol. InChIKey UDLAXUPVISWZSI-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.