PF-06869206 - ≥98% , CAS No.2227425-05-8

CAS: 2227425-05-8 Cat. No.: P412139 분자식: C15H14ClF3N4O2 분자량: 374.74 PubChem CID: 134159047
주문 가능
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
USA
독일 (EU)*
Price
Qty
5mg
P412139-5mg
3 재고 있음
—

US$78.90

US$118.90
저장 US$40.00 (33.64%)
10mg
P412139-10mg
2 재고 있음
—

US$151.90

US$227.90
저장 US$76.00 (33.35%)
25mg
P412139-25mg
2 재고 있음
—

US$332.90

US$499.90
저장 US$167.00 (33.41%)
50mg
P412139-50mg
1 재고 있음
—

US$598.90

US$898.90
저장 US$300.00 (33.37%)
Enter a quantity for the sizes you want to add.
🧪
Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Information

PF-06869206 is an orally selective bioavailable inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1) with IC50 of 380 nM.

Specifications

사양 및 순도
≥98%
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
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작업 유형
INHIBITOR
순수함
≥98%
이름과 식별자
Pubchem Sid
정식 스마일
CC1=C(C2=C(N1)C(=C(C(=N2)C(F)(F)F)C#N)N3CCOC(C3)CO)Cl
IUPAC Name
3-chloro-7-[(2S)-2-(hydroxymethyl)morpholin-4-yl]-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
InChIKey
ATFQBBCQZKVZJN-QMMMGPOBSA-N
INCHI
1S/C15H14ClF3N4O2/c1-7-10(16)11-12(21-7)13(23-2-3-25-8(5-23)6-24)9(4-20)14(22-11)15(17,18)19/h8,21,24H,2-3,5-6H2,1H3/t8-/m0/s1
이성체 SMILES
CC1=C(C2=C(N1)C(=C(C(=N2)C(F)(F)F)C#N)N3CCO[C@@H](C3)CO)Cl
PubChem CID
134159047
분자량
374.74

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
분류Pyrrolopyridines
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPyrrolopyridines
Alternative Parents Polyhalopyridines  Dialkylarylamines  Hydroxypyridines  Aminopyridines and derivatives  2-halopyridines  Morpholines  Pyrroles  Heteroaromatic compounds  1,3-aminoalcohols  Oxacyclic compounds  Nitriles  Dialkyl ethers  Azacyclic compounds  Organopnictogen compounds  Organofluorides  Organochlorides  Hydrocarbon derivatives  Alkyl fluorides  Alcohols and polyols  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Pyrrolopyridine - Polyhalopyridine - Dialkylarylamine - Tertiary aliphatic/aromatic amine - 2-halopyridine - Hydroxypyridine - Aminopyridine - Pyridine - Oxazinane - Morpholine - Heteroaromatic compound - Pyrrole - 1,3-aminoalcohol - Tertiary amine - Oxacycle - Azacycle - Nitrile - Ether - Dialkyl ether - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organochloride - Organohalogen compound - Amine - Alkyl halide - Alkyl fluoride - Alcohol - Aromatic heteropolycyclic compound
설명This compound belongs to the class of organic compounds known as pyrrolopyridines. These are compounds containing a pyrrolopyridine moiety, which consists of a pyrrole ring fused to a pyridine. Pyrrole is 5-membered ring consisting of four carbon atoms and one nitrogen atom. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center.
External Descriptors Not available
3D 구조
상호 작용 화학 구조 모델





관련 대상(인간)
SLC34A1 Tchem Sodium-dependent phosphate transport protein 2A (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC34A1 Tchem Sodium-dependent phosphate transport protein 2A (35 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC34A2 Tchem Sodium-dependent phosphate transport protein 2B (105 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC20A2 Tbio Sodium-dependent phosphate transporter 2 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
관련 대상(비인간)
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc34a3 Sodium-dependent phosphate transport protein 2C (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate Type날짜항목
B2419537Certificate of AnalysisJan 08, 2024 P412139
B2419538Certificate of AnalysisJan 08, 2024 P412139
B2419539Certificate of AnalysisJan 08, 2024 P412139
B2419543Certificate of AnalysisJan 08, 2024 P412139
B2419544Certificate of AnalysisJan 08, 2024 P412139
B2419545Certificate of AnalysisJan 08, 2024 P412139
B2419546Certificate of AnalysisJan 08, 2024 P412139
B2419548Certificate of AnalysisJan 08, 2024 P412139
화학 및 물리적 특성
분자량374.740 g/mol
XLogP31.900
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count2
Exact Mass374.076 Da
Monoisotopic Mass374.076 Da
Topological Polar Surface Area85.200 Ų
Heavy Atom Count25
Formal Charge0
Complexity543.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
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