개요 Specifications 이름과 식별자 Documentation Advanced Data Taxonomic Classification 3D 구조 관련 대상(인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 자주 묻는 질문과 기사 Citations of This Product 솔루션 계산기 리뷰

🧪

Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Argon charged,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 5607 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Product introduction：

Premium Grade EDC is our highest quality formulation of this popular carbodiimide crosslinker, specially characterized for applications where product integrity and risk minimization are paramount.

Features of Premium Grade EDC:

• EDC—carbodiimide crosslinker for conjugation between carboxylates and amines
• High quality—identity and purity confirmed by several tests
• Product integrity—enhanced level of testing and characterization compared to standard grade
• Lot retention—ample supply of past lots retained to ensure future process testing
• Change management—Change Control Notification (CCN) service
• Consistent manufacture—batch-specific manufacturing documentation review

Compared to the standard grade product, Premium Grade EDC provides more clearly defined quality and product support by including (a) increased analytical testing and product characterization, (b) greater batch-specific information and quality assurance review, (c) extensive lot sample retention and (d) change control notification. EDC is 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride, a water-soluble carbodiimide crosslinker that activates carboxyl groups for spontaneous reaction with primary amines, enabling peptide immobilization and hapten-carrier protein conjugation. In the presence of N-hydroxysulfosuccinimide (sulfo-NHS), EDC can be used to convert carboxyl groups to amine-reactive sulfo-NHS esters. This is accomplished by mixing the EDC with a carboxyl containing molecule and adding sulfo-NHS.

Specifications of Premium Grade EDC
We manufacture crosslinking reagents to ensure the highest possible overall product integrity, consistency and performance for the intended research applications.
• Visual: White crystalline powder, free of foreign matter
• Identity: IR scan shows only peaks characteristic of EDC
• Water content: Karl Fischer titration, ≤ 2%
• Trace metals: All metals, including lead, ≤ 50 ppm
• Elemental analysis: Reported values for C, H, and N

Applications:
• Conjugate carboxyl and amino groups among peptides and proteins
• Couple haptens to immunogenic carrier proteins (e.g.,attach a peptide to KLH)
•Immobilize peptide antigens to affinity-purify antibodies
• Create NHS-activated, amine-reactive labeling compounds
• Crosslink proteins to carboxyl coated beads or surfaces
• Activate nanoparticles with amine-reactive sulfo-NHS esters

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

• Reactive Moiety:Carbodiimide

• Crosslinker Type:Heterobifunctional

• Form:Solid:

• Spacer:Short(<10 Å)

• Labeling Method:Chemical Labeling

• Spacer Arm Length:0.0 Å

Specifications

동의어

1-Ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride | 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride | EDC·HCl | EDAC·HCL | EDCI·HCl

보관 조건

Store at -20°C,Argon charged,Desiccated

배송

Ice chest + Ice pads

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

이름과 식별자

Pubchem Sid

528766798

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528766798

정식 스마일

CCN=C=NCCCN(C)C.Cl

InChIKey

FPQQSJJWHUJYPU-UHFFFAOYSA-N

INCHI

1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H

이성체 SMILES

CCN=C=NCCCN(C)C.Cl

WGK 독일

RTECS

FF2200000

대체 CAS

7084-11-9

분자량

191.70

Beilstein

5764110

Reaxy-Rn

5764110

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5764110&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic nitrogen compounds
  - 분류 Organonitrogen compounds
    - Subclass Amines
      - Level5 Tertiary amines
        Level6 Trialkylamines

Kingdom	Organic compounds
Superclass	Organic nitrogen compounds
분류	Organonitrogen compounds
Subclass	Amines
Intermediate Tree Nodes	Tertiary amines
Direct Parent	Trialkylamines
Alternative Parents	Propargyl-type 1,3-dipolar organic compounds Carbodiimides Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives
Molecular Framework	Aliphatic acyclic compounds
Substituents	Tertiary aliphatic amine - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carbodiimide - Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Aliphatic acyclic compound
설명	This compound belongs to the class of organic compounds known as trialkylamines. These are organic compounds containing a trialkylamine group, characterized by exactly three alkyl groups bonded to the amino nitrogen.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D 구조

관련 대상(인간)

A498 (42825 Activities)

Lot Number	Certificate Type	날짜	항목
A2416088	Certificate of Analysis	Jan 05, 2024	A638754
A2416089	Certificate of Analysis	Jan 05, 2024	A638754
A2416090	Certificate of Analysis	Jan 05, 2024	A638754
A2416091	Certificate of Analysis	Jan 05, 2024	A638754

용해성	Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.
감도	Moisture sensitive; Heat sensitive
녹는점(°C)	115-118°C
분자량	191.700 g/mol
XLogP3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	5
Exact Mass	191.119 Da
Monoisotopic Mass	191.119 Da
Topological Polar Surface Area	28.000 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	134.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Premium-Grade EDC , CAS No.25952-53-8

Storage & shipping

Quality documents

Literature proof

개요

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

고객 리뷰

📚 Citations by Application

View related series

관련 상품