Prothrombin, CAS No.9001-26-7

CAS: 9001-26-7 Cat. No.: np330888

GRADE & PURITY BioReagent, Native, ≥95%(SDS-PAGE), from Human plasma; Pre-lyophilization Protein Concentration: See COA

Accession #

P00734

개요

Prepared from fresh frozen human plasma. Human Prothrombin is a glycoprotein of molecular weight 72,000, and consists of a single polypeptide chain. Activation of Prothrombin by Factor Va, Xa and phospholipids yields the serine protease Thrombin. The human Prothrombin is >95% via SDS-PAGE and shows no reduction upon incubation with 2- mercaptoethanol.

Extinction Coefficient (1%) = 13.6

The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

Specifications

Product Name

Prothrombin, CAS No.9001-26-7

동의어

Prothrombin from Human plasma | Human Prothrombin | Human Prothrombin (Factor II) Native Protein | Prothrombin, Human Plasma | Coagulation factor II | F2 | PT | THPH1 | RPRGL2

등급

BioReagent, Native

사양 및 순도

BioReagent, Native, ≥95%(SDS-PAGE), from Human plasma; Pre-lyophilization Protein Concentration: See COA

생화학 및 생리적 메커니즘

Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Activates coagulation

가입 번호

P00734

예상 분자량

72 kDa

CAS

9001-26-7

분자 유형

Protein

보관 및 배송

집중력

from Human plasma; Pre-lyophilization Protein Concentration: See COA

재구성

We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.

보관 조건

Store at 2-8°C

배송

Wet ice

안정성 및 스토리지

Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot and freeze at -80℃.