Ractopamine - Moligand™, ≥97% , Agonist of β 2-adrenoceptor;Agonist of TA 1 receptor, CAS No.97825-25-7, Agonist of β 2-adrenoceptor;Agonist of TA 1 receptor

CAS: 97825-25-7 Cat. No.: R613085 분자식: C₁₈H₂₃NO₃ 분자량: 301.38

GRADE & PURITY Moligand™, ≥97%

Synonyms

Optaflexx | Ractopamina [Spanish] | Ractopamine [INN] | NCGC00164602-03 | DB11541 | AKOS015889248 | UNII-57370OZ3P1 | FT-0600189 | (+/-)-all-rac-p-Hydroxy-alpha-(((3-(p-hydroxyphenyl)-1-methylpropyl)amino)methyl)benzyl alcohol | 4-(1-hydroxy-2-{[4-(4-hydr

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

개요

Ractopamine is a potent β-adrenergic receptor (βAR) agonist with Kd value of ~25 nM for pig β1AR and β2AR. Ractopamine is linked to protein metabolism. Ractopamine is structurally similar to the natural catecholamines epinephrine and norepinephrine, and binds with high affinity to βAR in pig adipose and muscle tissue. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs

Specifications

동의어

Optaflexx | Ractopamina [Spanish] | Ractopamine [INN] | NCGC00164602-03 | DB11541 | AKOS015889248 | UNII-57370OZ3P1 | FT-0600189 | (+/-)-all-rac-p-Hydroxy-alpha-(((3-(p-hydroxyphenyl)-1-methylpropyl)amino)methyl)benzyl alcohol | 4-(1-hydroxy-2-{[4-(4-hydr

사양 및 순도

Moligand™, ≥97%

보관 조건

Store at 2-8°C,Argon charged

배송

Wet ice

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등급

Moligand™

작업 유형

AGONIST

작동 메커니즘

Agonist of β 2-adrenoceptor;Agonist of TA 1 receptor

순수함

≥97%

이름과 식별자

• Pubchem Sid: 528766921
• 정식 스마일: CC(CCC1=CC=C(C=C1)O)NCC(C2=CC=C(C=C2)O)O
• IUPAC Name: 4-[3-[[2-hydroxy-2-(4-hydroxyphenyl)ethyl]amino]butyl]phenol
• InChIKey: YJQZYXCXBBCEAQ-UHFFFAOYSA-N
• INCHI: 1S/C18H23NO3/c1-13(2-3-14-4-8-16(20)9-5-14)19-12-18(22)15-6-10-17(21)11-7-15/h4-11,13,18-22H,2-3,12H2,1H3
• 이성체 SMILES: CC(CCC1=CC=C(C=C1)O)NCC(C2=CC=C(C=C2)O)O
• 대체 CAS: 97825-25-7
• MeSH 용어: 4-hydroxy-alpha-(((3-(4-hydroxyphenyl)-1-methylpropyl)amino)methyl)benzenemethanol;El 737;EL-737;LY 031537;LY-031537;ractopamine;ractopamine hydrochloride
• 분자량: 301.38

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • 분류 Phenols
      • Subclass 1-hydroxy-2-unsubstituted benzenoids

• Kingdom: Organic compounds
• Superclass: Benzenoids
• 분류: Phenols
• Subclass: 1-hydroxy-2-unsubstituted benzenoids
• Intermediate Tree Nodes: Not available
• Direct Parent: 1-hydroxy-2-unsubstituted benzenoids
• Alternative Parents: Aralkylamines Benzene and substituted derivatives Secondary alcohols 1,2-aminoalcohols Dialkylamines Organopnictogen compounds Hydrocarbon derivatives Aromatic alcohols
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: 1-hydroxy-2-unsubstituted benzenoid - Aralkylamine - Monocyclic benzene moiety - 1,2-aminoalcohol - Secondary alcohol - Secondary amine - Secondary aliphatic amine - Organic oxygen compound - Aromatic alcohol - Alcohol - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Amine - Hydrocarbon derivative - Organopnictogen compound - Aromatic homomonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as 1-hydroxy-2-unsubstituted benzenoids. These are phenols that a unsubstituted at the 2-position.
• External Descriptors: secondary alcohol - benzyl alcohols - secondary amino compound - polyphenol

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

TAAR1 Tclin Trace amine-associated receptor 1 (0 Activities)

Discover Target: TAAR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRB2 Tclin Beta-2 adrenergic receptor (0 Activities)

Discover Target: ADRB2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)

Discover Target: ADRB2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PMP22 Tbio Peripheral myelin protein 22 (699 Activities)

Discover Target: PMP22

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)

Discover Target: GLS

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POU2F1 Tbio POU domain, class 2, transcription factor 1 (93 Activities)

Discover Target: POU2F1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

관련 대상(비인간)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 감도: Moisture sensitive
• 분자량: 301.400 g/mol
• XLogP3: 2.700
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 301.168 Da
• Monoisotopic Mass: 301.168 Da
• Topological Polar Surface Area: 72.700 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 297.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

참고 문헌

1. Jin Yuting, Yan Rongfang, Wang Shuo, Wang Xianghong, Zhang Xuemei, Tang Yiwei.  (2022)  Dipeptide nanoparticle and aptamer-based hybrid fluorescence platform for enrofloxacin determination.  MICROCHIMICA ACTA,  189  (3): (1-8).  [PMID:35147788] [10.1007/s00604-022-05182-z]

2. Yingjie Zhao, Li Tian, Xin Zhang, Zhuo Sun, Xiangyu Shan, Qian Wu, Ruizhan Chen, Juan Lu.  (2021)  A novel molecularly imprinted polymer electrochemiluminescence sensor based on Fe2O3@Ru(bpy)32+ for determination of clenbuterol.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2021.130822]

3. Li Ying, Su Ruifang, Xu Jingyue, Bie Jiaxin, Sun Rui, Wang Luokai, Liu Xin, Sun Chunyan.  (2018)  Aptamers-Based Sensing Strategy for 17β-Estradiol Through Fluorescence Resonance Energy Transfer Between Oppositely Charged CdTe Quantum Dots and Gold Nanoparticles.  JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,  18  (3): (1517-1527).  [PMID:29448625] [10.1166/jnn.2018.14235]

4. Fang Li, Ruihua Zhang, Huaibin Kang, Yonggang Hu, Yunhong Liu, Junya Zhu.  (2017)  Facile and sensitive detection of clenbuterol in pork using a personal glucose meter.  Analytical Methods,  9  (46): (6507-6512).  [PMID:] [10.1039/C7AY01826F]

5. Zheng Mingyu, Qian Xinmei, Li Chunxiang, Wang Jinglun, Huang Haowen, Deng Keqin.  (2024)  A renewable screen-printed electrode based on magnetic NiCo@N-doped carbon nanotubes derived from Co-MOF for ractopamine detection.  MICROCHIMICA ACTA,  191  (8): (1-10).  [PMID:38985347] [10.1007/s00604-024-06507-w]

6. Sujun Liu, Kai Shi.  (2024)  Asymmetric CRISPR-Cas12a powered electrochemical aptasensor for clenbuterol detection based on competitive gRNA mediated cascade signal amplification.  FOOD CHEMISTRY,      [PMID:39536590] [10.1016/j.foodchem.2024.141928]

7. Lu Yang, Tong Zhai, Jing Wang, Hong Zheng, Jing-Min Liu, Shuo Wang.  (2024)  One simple and integrated nano-inspection platform for high-throughput detection of clenbuterol.  FOOD CHEMISTRY,      [PMID:39406141] [10.1016/j.foodchem.2024.141579]

8. Runxian Li, Decheng Suo, Zhengjie Yu, Zhiming Xiao, Peiling Wei, Shi Wang, Yuchao Feng, Xia Fan.  (2025)  A traffic light-fluorescent lateral flow immunoassay with dual-color quantum dot nanobeads for the simultaneous detection of ractopamine and clenbuterol.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.114042]

9. Yichen Li, Xuan Wu, Furun Wang, Lei Li, Hongjiao Zhang.  (2026)  Green-emitting zinc silicate persistent luminescent nanospheres for autofluorescence-free biosensing of ractopamine.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2026.117732]