≥96%(HPLC) 최소한의 기준선 간섭이 필요한 민감한 크로마토그래피 및 분석 워크플로우용.
Store at -20°C,Argon charged Ice chest + Ice pads 출고. 정확한 사양은 로트별 COA를 확인하세요.
SDS, COA, 데이터시트, 사양서를 다운로드할 수 있습니다. 로트별 COA는 로트 번호 조회를 통해 확인할 수 있습니다.
크로마토그래피, 유기 합성 및 교차 커플링 반응 분야의 동료 심사 논문 0편에서 인용되었습니다.
Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9.
Application：
Raptinal showed complete cytochrome c release within 30 minutes and caspase-3 activation within one hour of exposure (10 μM). Despite its general cytotoxicity in both cancer and non-cancer cell cultures (Cell death induction EC50 = 0.6-3.4 μM in 24 hr), no hematologic toxicity was observed 7 days following single 60 mg/kg i.v. dosing in mice. Studies show that daily i.p. injection (20 mg/kg) is efficacious in suppressing murine B16-F10 melanoma and 4T1 breast cancer expansion in vivo (by ~60% and 50% in 6 days, respectively).
위험성, 취급, 보관 및 규제 준수를 포괄하는 종합 문서.
<<<<<<< HEAD SDS 다운로드 → ======= SDS 다운로드 → >>>>>>> release248-p3Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| 분류 | Fluorenes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Fluorenes |
| Alternative Parents | Organic oxides Hydrocarbon derivatives Aldehydes |
| Molecular Framework | Aromatic homopolycyclic compounds |
| Substituents | Fluorene - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aldehyde - Aromatic homopolycyclic compound |
| 설명 | This compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 날짜 | 항목 |
|---|---|---|---|
 H2529565 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| H2529566 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| H2529567 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| J2616092 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| F2415182 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415183 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415204 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415208 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415217 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415241 | Certificate of Analysis | May 08, 2024 | R404974 |
| 용해성 | DMSO: 18.0 mg/mL (46.6 mM), Sonification and heating to 60℃ are recommended. |
|---|---|
| 감도 | Air Sensitive,Heat Sensitive |
| 녹는점(°C) | 219 °C |
| 분자량 | 386.400 g/mol |
| XLogP3 | 4.900 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 3 |
| Exact Mass | 386.131 Da |
| Monoisotopic Mass | 386.131 Da |
| Topological Polar Surface Area | 34.100 Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 580.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
