SC-26196 - ≥98% , CAS No.218136-59-5

CAS: 218136-59-5 Cat. No.: S276482 분자식: C27H29N5 분자량: 423.56 PubChem CID: 9845201
주문 가능
GRADE & PURITY ≥98%
Synonyms
2,2-Diphenyl-5-[4-[(E)-pyridin-3-ylmethylideneamino]piperazin-1-yl]pentanenitrile | a,a-diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
USA
독일 (EU)*
Price
Qty
5mg
S276482-5mg
3 재고 있음
—

US$39.90

US$59.90
저장 US$20.00 (33.39%)
10mg
S276482-10mg
3 재고 있음
—

US$70.90

US$106.90
저장 US$36.00 (33.68%)
25mg
S276482-25mg
2 재고 있음
—

US$154.90

US$232.90
저장 US$78.00 (33.49%)
50mg
S276482-50mg
2 재고 있음
—

US$202.90

US$304.90
저장 US$102.00 (33.45%)
Enter a quantity for the sizes you want to add.
🧪
Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Product description:

SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC50=0.2 µM in a rat liver microsomal assay). Antiinflammatory properties.


Application:

SC-26196 has been used as an inhibitor of delta6 (Δ6) fatty acid desaturase:

in mouse inner medullary collecting duct (IMCD3) and human (female) embryonic kidney (HEK) 293 cell culture as Dulbecco′s modified eagle′s medium (DMEM) component

in hepatic HepG2 cells

in glioblastoma cell lines to test its effect post-radiation treatments

Specifications

동의어
2,2-Diphenyl-5-[4-[(E)-pyridin-3-ylmethylideneamino]piperazin-1-yl]pentanenitrile | a,a-diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile
사양 및 순도
≥98%
생화학 및 생리적 메커니즘
Selective Δ6 desaturase inhibitor (IC 50 =0.2 μM in vitro ). It displays selectivity over Δ5 and Δ9 desaturases (IC 50 values are >200 μM in vitro). Exhibits anti inflammatory properties in a mouse edema model. Eliminates CSCs from ovarian cancer cell lin
보관 조건
Protected from light,Store at -20°C
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
참고
Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
순수함
≥98%
이름과 식별자
Pubchem Sid
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/504764964
정식 스마일
C1CN(CCN1CCCC(C#N)(C2=CC=CC=C2)C3=CC=CC=C3)N=CC4=CN=CC=C4
IUPAC Name
2,2-diphenyl-5-[4-[(E)-pyridin-3-ylmethylideneamino]piperazin-1-yl]pentanenitrile
InChIKey
QFYKXKMYVYOUNJ-JBASAIQMSA-N
INCHI
1S/C27H29N5/c28-23-27(25-10-3-1-4-11-25,26-12-5-2-6-13-26)14-8-16-31-17-19-32(20-18-31)30-22-24-9-7-15-29-21-24/h1-7,9-13,15,21-22H,8,14,16-20H2/b30-22+
이성체 SMILES
C1CN(CCN1CCCC(C#N)(C2=CC=CC=C2)C3=CC=CC=C3)/N=C/C4=CN=CC=C4
PubChem CID
9845201
분자량
423.56

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
분류Benzene and substituted derivatives
SubclassDiphenylacetonitriles
Intermediate Tree Nodes Not available
Direct ParentDiphenylacetonitriles
Alternative Parents Diphenylmethanes  Phenylbutylamines  N-alkylpiperazines  Aralkylamines  Pyridines and derivatives  Heteroaromatic compounds  Trialkylamines  Nitriles  Hydrazones  Azacyclic compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Diphenylacetonitrile - Diphenylmethane - Phenylbutylamine - N-alkylpiperazine - Aralkylamine - 1,4-diazinane - Piperazine - Pyridine - Heteroaromatic compound - Tertiary aliphatic amine - Tertiary amine - Nitrile - Carbonitrile - Hydrazone - Organoheterocyclic compound - Azacycle - Amine - Hydrocarbon derivative - Organonitrogen compound - Cyanide - Organic nitrogen compound - Aromatic heteromonocyclic compound
설명This compound belongs to the class of organic compounds known as diphenylacetonitriles. These are cyclic aromatic compounds containing a diphenylacetonitrile moiety, which consists of a diphenylmethane linked to and acetonitrile to form 2,2-diphenylacetonitrile.
External Descriptors Not available
3D 구조
상호 작용 화학 구조 모델





작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate Type날짜항목
K2219129Certificate of AnalysisSep 07, 2026 S276482
K2219127Certificate of AnalysisSep 07, 2026 S276482
K2219126Certificate of AnalysisSep 07, 2026 S276482
K2219128Certificate of AnalysisSep 07, 2026 S276482
F2518099Certificate of AnalysisJun 24, 2025 S276482
화학 및 물리적 특성
용해성Soluble in DMSO to 10\xa0mM
분자량423.600 g/mol
XLogP34.400
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Exact Mass423.242 Da
Monoisotopic Mass423.242 Da
Topological Polar Surface Area55.500 Ų
Heavy Atom Count32
Formal Charge0
Complexity599.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
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