Senexin A - ≥98%(HPLC) , CAS No.1780390-76-2

CAS: 1780390-76-2 Cat. No.: S288272 분자식: C₁₇H₁₄N₄.HCl 분자량: 310.78 PubChem CID: 90488980

GRADE & PURITY ≥98%(HPLC)

Synonyms

4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitrile hydrochloride

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

동의어

4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitrile hydrochloride

사양 및 순도

≥98%(HPLC)

생화학 및 생리적 메커니즘

Cyclin-dependent kinase 8 (cdk8) inhibitor (IC50= 280 nM). Also binds to cdk19 in an ATP-competitive manner. Inhibits p21-induced transcription. Reversesdoxorubicin-induced tumor-promoting paracrine activitiesin vivo.

보관 조건

Store at 2-8°C

배송

Wet ice

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순수함

≥98%(HPLC)

이름과 식별자

• 정식 스마일: C1=CC=C(C=C1)CCNC2=NC=NC3=C2C=C(C=C3)C#N.Cl
• IUPAC Name: 4-(2-phenylethylamino)quinazoline-6-carbonitrile;hydrochloride
• InChIKey: POENYXHGUHRXFR-UHFFFAOYSA-N
• INCHI: 1S/C17H14N4.ClH/c18-11-14-6-7-16-15(10-14)17(21-12-20-16)19-9-8-13-4-2-1-3-5-13;/h1-7,10,12H,8-9H2,(H,19,20,21);1H
• 이성체 SMILES: C1=CC=C(C=C1)CCNC2=NC=NC3=C2C=C(C=C3)C#N.Cl
• PubChem CID: 90488980
• 분자량: 310.78

화학 및 물리적 특성

• 용해성: Solvent:DMSO, Max Conc. mg/mL: 31.08, Max Conc. mM: 100

자주 묻는 질문

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1780390-76-2, the molecular formula is C??H??N?.HCl, and the molecular weight is 310.78 g/mol. InChIKey POENYXHGUHRXFR-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.