SG-094 - ≥95% , CAS No.S658832

CAS: S658832 Cat. No.: S658832 분자식: C₃₀H₂₉NO₃ 분자량: 451.56

등급 & 순도 ≥95%

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

개요

SG-094 is a potent TPC2 inhibitor with antiproliferative effects. SG-094 can be used for the research of cancer.

Appearance:Oil

IC50& Target:TPC2

In Vitro:SG-094 (72 hours) shows antiproliferative effects against RIL175 cells, with an IC 50 of 3.7 μM. SG-094 (10 μM) blocks PI(3,5)P 2 -elicited TPC2 currents on isolated endolysosomes from HEK293 cells expressing TPC2-EGFP. SG-094 (10 μM; pretreated

In Vivo:SG-094 (90 nmol/kg; every 2-3 days over a 10-day timescale) inhibits hepatocellular carcinoma (HCC) tumor growth in mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: C57Bl/6-Tyr mice w

Biological Activity:SG-094 is a potent TPC2 inhibitor with antiproliferative effects. SG-094 can be used for the research of cancer.

사양

사양 및 순도

≥95%

보관 조건

Store at 2-8°C,Protected from light

배송

Wet ice

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순수함

≥95%

이름과 식별자

정식 스마일

COC1=C(OC2=CC=CC=C2)C=C(C(CC3=CC=C(OC4=CC=CC=C4)C=C3)N(C)CC5)C5=C1

분자량

451.56

화학 및 물리적 특성

• 용해성: Methanol : 125 mg/mL (276.82 mM; Need ultrasonic) DMSO : 100 mg/mL (221.45 mM; Need ultrasonic)