SKI-178 - ≥98% , CAS No.1259484-97-3

CAS: 1259484-97-3 Cat. No.: S413386 분자식: C₂₁H₂₂N₄O₄ 분자량: 394.4 EC 번호: 162-793-0 PubChem CID: 1356476

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Information

SKI-178 is a potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2. SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines.

Specifications

사양 및 순도

≥98%

생화학 및 생리적 메커니즘

SKI-178 is a potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2. SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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순수함

≥98%

이름과 식별자

• Pubchem Sid: 504760468
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504760468
• 정식 스마일: CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)C3=CC(=C(C=C3)OC)OC
• IUPAC Name: N-[1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
• InChIKey: GMFUWEBOUKIKRP-UHFFFAOYSA-N
• INCHI: 1S/C21H22N4O4/c1-13(15-7-10-19(28-3)20(11-15)29-4)22-25-21(26)18-12-17(23-24-18)14-5-8-16(27-2)9-6-14/h5-12H,1-4H3,(H,23,24)(H,25,26)
• 이성체 SMILES: CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)C3=CC(=C(C=C3)OC)OC
• PubChem CID: 1356476
• 분자량: 394.4