SKI-I - ≥90% , CAS No.306301-68-8

CAS: 306301-68-8 Cat. No.: S275155 분자식: C25H18N4O2 분자량: 406.44 EC 번호: 999-234-2 PubChem CID: 137269090

등급 & 순도 ≥90%

Synonyms

5-(2-Naphthalenyl)-1H-pyrazole-3-carboxylicacid2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

개요

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

사양

동의어

5-(2-Naphthalenyl)-1H-pyrazole-3-carboxylicacid2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide

사양 및 순도

≥90%

생화학 및 생리적 메커니즘

Specific non-lipid sphingosine kinase (SK) inhibitor. Inhibits SK1 and SK2. Inhibits sphingosine 1-phosphate (S1P) production and pro-apoptotic. Induces autophagy. Cell permeable and active in vivo and in vitro .

보관 조건

Store at -20°C,Desiccated

배송

Ice chest + Ice pads

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참고

Unstable; make up solutions fresh and use immediately. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

순수함

≥90%

이름과 식별자

정식 스마일

C1C(NNC1C(=O)NN=CC2=C(C=CC3=CC=CC=C32)O)C4=CC5=CC=CC=C5C=C4

IUPAC Name

N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-5-naphthalen-2-ylpyrazolidine-3-carboxamide

InChIKey

LMCALHGHWCFFHD-CVKSISIWSA-N

INCHI

1S/C25H22N4O2/c30-24-12-11-17-6-3-4-8-20(17)21(24)15-26-29-25(31)23-14-22(27-28-23)19-10-9-16-5-1-2-7-18(16)13-19/h1-13,15,22-23,27-28,30H,14H2,(H,29,31)/b26-15+

PubChem CID

137269090

분자량

406.44

화학 및 물리적 특성

• 용해성: Soluble in DMSO to 100 mM