아스코르브산 나트륨 - 세포 배양의 경우, ≥99% , CAS No.134-03-2

CAS: 134-03-2 Cat. No.: S105026 분자식: C₆H₇NaO₆ 분자량: 198.11 Beilstein Registry Number: 3767246 EC 번호: 205-126-1 PubChem CID: 23667548

GRADE & PURITY for Cell culture, ≥99%

Synonyms

L-Ascorbic acid, monosodium salt | sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate | Vitamin C Sodium Salt | (+)-Sodium L-ascorbate | SODIUM ASCORBATE | 2,3-Didehydro-L-theo-hexono-1,4-lactone sodium enolate | SODIUM ASCORBATE (US

Storage

아르곤 충전

Shipped In

보통

개요

아스코르브산 나트륨은 잠재적 항산화제이며 비타민 C(L-아스코르브산)의 유도체입니다.[1][2] 식품 첨가물로 널리 사용됩니다.[1] 또한 SA는 배양 중인 신경모세포종 세포에서 블레오마이신 황산염, R020-1724(순환 뉴클레오티드 포스포디에스 테라제 억제제), 프로스타글란딘 E1 및 부티레이트 나트륨의 성장 지연 활동을 향상시킵니다.[3] 높은 수준의 SA는 쥐에서 2단계 방광 발암을 유도합니다.[1] 콜라겐 생성 억제제와 함께 L-아스코르브산 나트륨은 피부 흉터와 켈로이드를 치료하는 데 사용됩니다.

응용 분야：아스코르브산 나트륨
아스코르브산 나트륨이 사용되었습니다:
- 세포 배양 배지에서 H2O2를 생성하기 위해;
- 세포 투과성 인공 전자 공여체인 N,N,N′,N′-테트라메틸-p-페닐렌디아민(TMPD)의 환원제로서;
- 정상적인 사람의 피부와 진피 지방에서 추출한 섬유아세포 배양에서 콜라겐과 탄력 섬유 생성에 미치는 영향을 연구하기 위해

Specifications

동의어

L-Ascorbic acid, monosodium salt | sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate | Vitamin C Sodium Salt | (+)-Sodium L-ascorbate | SODIUM ASCORBATE | 2,3-Didehydro-L-theo-hexono-1,4-lactone sodium enolate | SODIUM ASCORBATE (US

사양 및 순도

세포 배양의 경우, ≥99%

보관 조건

아르곤 충전

배송

보통

등급

세포 배양용

순수함

≥99%

이름과 식별자

Pubchem Sid

508813564

정식 스마일

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

IUPAC Name

sodium;(2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate

InChIKey

PPASLZSBLFJQEF-RXSVEWSESA-M

INCHI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

이성체 SMILES

C([C@@H]([C@@H]1C(=C(C(=O)O1)O)[O-])O)O.[Na+]

WGK 독일

1

RTECS

CI7671000

PubChem CID

23667548

분자량

198.11

Beilstein

3767246

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 분류 Dihydrofurans
      • Subclass Furanones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 분류: Dihydrofurans
• Subclass: Furanones
• Intermediate Tree Nodes: Not available
• Direct Parent: Butenolides
• Alternative Parents: Vinylogous acids Enoate esters Secondary alcohols Lactones 1,2-diols Oxacyclic compounds Monocarboxylic acids and derivatives Primary alcohols Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: 2-furanone - Enoate ester - Alpha,beta-unsaturated carboxylic ester - Vinylogous acid - 1,2-diol - Carboxylic acid ester - Lactone - Secondary alcohol - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Oxacycle - Organic alkali metal salt - Hydrocarbon derivative - Organic oxide - Organic zwitterion - Organic oxygen compound - Primary alcohol - Organooxygen compound - Alcohol - Carbonyl group - Organic salt - Organic sodium salt - Aliphatic heteromonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

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Discover Target: FFAR3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CRYAB Tchem Alpha-crystallin B chain (132 Activities)

Discover Target: CRYAB

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관련 대상(비인간)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

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작용 메커니즘

화학 및 물리적 특성

• 용해성: Soluble in water. Slightly soluble in alcohol. Insoluble in chloroform and ether.
• 감도: Light & Moisture & Air sensitive
• 특정 회전[α]: 105.5 ° (C=10, H2O)
• 녹는점(°C): 219-221°C
• 분자량: 198.110 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 198.014 Da
• Monoisotopic Mass: 198.014 Da
• Topological Polar Surface Area: 110.000 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 237.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3