Spermidine - UltraBio™, Suitable for molecular biology, ≥99.5%(GC) , CAS No.124-20-9

CAS: 124-20-9 Cat. No.: S755738 분자식: C₇H₁₉N₃ 분자량: 145.25 Beilstein Registry Number: 1698591 EC 번호: 204-689-0

GRADE & PURITY UltraBio™, Suitable for molecular biology, ≥99.5%(GC)

Synonyms

1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane | 1,8-Diamino-4-azaoctane | N-(3-Aminopropyl)-1,4-diaminobutane | N1-(3-Aminopropyl)butane-1,4-diamine

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

개요

Spermidine is a polyamine and a trivalent organic cation.Spermidine is a naturally occurring polyamine compound with diverse biochemical properties. It plays a vital role in gene expression, participating in DNA replication, transcription, and translation processes. Spermidine is crucial for cell growth, proliferation, and differentiation, influencing cell cycle progression and tissue development. It possesses antioxidant activity, safeguarding cells against oxidative stress by scavenging free radicals. Spermidine also stimulates autophagy, promoting the turnover of damaged organelles and protein aggregates for cellular homeostasis. With neuroprotective effects, it supports neuronal survival, synaptic plasticity, and guards against neurodegenerative diseases. Additionally, spermidine modulates cellular signaling pathways involved in inflammation and immune responses.

Application:

Spermidine has been used:

• as a component of chromosome isolation buffer
• as a component of transcription buffer
• as a component of homogenization buffer

Specifications

동의어

1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane | 1,8-Diamino-4-azaoctane | N-(3-Aminopropyl)-1,4-diaminobutane | N1-(3-Aminopropyl)butane-1,4-diamine

사양 및 순도

UltraBio™, Suitable for molecular biology, ≥99.5%(GC)

생화학 및 생리적 메커니즘

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity. Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Sti

보관 조건

Store at 2-8°C,Protected from light,Argon charged

배송

Wet ice

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등급

Suitable for molecular biology, UltraBio™

순수함

≥99.5%(GC)

이름과 식별자

PH

12.0-13.5 (25 °C, 1 M in H 2 O)

정식 스마일

NCCCCNCCCN

IUPAC Name

N'-(3-aminopropyl)butane-1,4-diamine

InChIKey

ATHGHQPFGPMSJY-UHFFFAOYSA-N

INCHI

1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2

이성체 SMILES

C(CCNCCCN)CN

WGK 독일

3

UN 번호

2735

분자량

145.25

Beilstein

1698591

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • 분류 Organonitrogen compounds
      • Subclass Amines
        • Level5 Secondary amines
          • Level6 Dialkylamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• 분류: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Secondary amines
• Direct Parent: Dialkylamines
• Alternative Parents: Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Secondary aliphatic amine - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Primary aliphatic amine - Aliphatic acyclic compound
• 설명: This compound belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen.
• External Descriptors: triamine - polyazaalkane

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

화학 및 물리적 특성

• 용해성: H 2 O: 1 M at 20 °C, clear, colorless
• 감도: Light sensitive；Moisture sensitive；Light sensitive
• 굴절률: 1.4785-1.4805
• 발화점(°F): 230°F
• 발화점(°C): >110°
• 끓는점(°C): 128-130°C
• 녹는점(°C): 22-25°C
• 분자량: 145.250 g/mol
• XLogP3: -1.000
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 145.158 Da
• Monoisotopic Mass: 145.158 Da
• Topological Polar Surface Area: 64.099 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 56.800
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1