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TA-316 - ≥98% , CAS No.1429321-13-0
주문 가능
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
개요
TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells.
In Vitro
TA-316 (0.01-1000 nM; 4 days) stimulates UT-7/TPO and Ba/F3-HuMpl cells proliferation, with the EC 50 values of 0.3 and 0.65 nM, respectively. ?\nTA-316 (800 nM; 10 days) promotes biased megakaryopoiesis and upregulated MK lineage markers. ?\nTA-316 (200 nM; 4 days) preferentially enhances VEGFA and FGF2 expression. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: UT-7/TPO and Ba/F3-HuMpl cells Concentration: 0.01-1000 nM Incubation Time: 4 days Result: Stimulated UT-7/TPO and Ba/F3-HuMpl cell proliferation.
Form:Solid
Specifications
사양 및 순도
≥98%
생화학 및 생리적 메커니즘
TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells.
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
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순수함
≥98%
이름과 식별자
| 정식 스마일 | O=C(C1=CC=C(C(NCC2=CC=C(C(NCCO)=O)C=C2)=O)S1)N/N=C(C3=CSC(C4=CC=C(Br)C=C4)=C3O)\\C |
|---|---|
| PubChem CID | 78101785 |
| 분자량 | 641.56 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
| 용해성 | DMSO : 50 mg/mL (77.94 mM; ultrasonic and warming and heat to 60°C) |
|---|
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