TAK-041 - 10mM in DMSO , CAS No.1929519-13-0

CAS: 1929519-13-0 Cat. No.: T655704 분자식: C₁₈H₁₅F₃N₄O₃ 분자량: 392.33

등급 & 순도 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

TAK-041 is a potent and selective GPR139 agonist with an EC 50 of 22 nM. TAK-041 has the potential for the research of negative symptoms associated with schizophrenia.

In Vivo

TAK-041 (0.03-3 mg/kg; P.o.) improves social behavior in BALB/c mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: BALB/c mice Dosage: 0.03, 0.3, and 3 mg/kg Administration: P.o. Result: Dose-dependently improved the social behavior of BALB/c mice.

사양

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

TAK-041 is a potent and selective GPR139 agonist with an EC 50 of 22 nM. TAK-041 has the potential for the research of negative symptoms associated with schizophrenia.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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이름과 식별자

이성체 SMILES

C[C@@H](C1=CC=C(C=C1)OC(F)(F)F)NC(=O)CN2C(=O)C3=CC=CC=C3N=N2

MeSH 용어

2-(4-oxo-1,2,3-benzotriazin-3-yl)-N-((1S)-1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide;TAK-041;TAK041

분자량

392.33

관련 대상(인간)

GPR139 Tchem Probable G-protein coupled receptor 139 (0 Activities)

Discover Target: GPR139

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)