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SCN10A

설명Sodium channel protein type 10 subunit alpha

Gene and Protein Information

Gene ID6336
Uniprot Accession IDs Q9Y5Y9 A6NDQ1
Ensembl ID ENSP00000390600
Symbol PN3 SNS hPN3 FEPS2 Nav1.8
FamilyBelongs to the sodium channel (TC 1.A.1.10) family. Nav1.8/SCN10A subfamily.
Sequence
MEFPIGSLETNNFRRFTPESLVEIEKQIAAKQGTKKAREKHREQKDQEEKPRPQLDLKACNQLPKFYGELPAELIGEPLEDLDPFYSTHRTFMVLNKGRTISRFSATRALWLFSPFNLIRRTAIKVSVHSWFSLFITVTILVNCVCMTRTDLPEKIEYVFTVIYTFEALIKILARGFCLNEFTYLRDPWNWLDFSVITLAYVGTAIDLRGISGLRTFRVLRALKTVSVIPGLKVIVGALIHSVKKLADVTILTIFCLSVFALVGLQLFKGNLKNKCVKNDMAVNETTNYSSHRKPDIYINKRGTSDPLLCGNGSDSGHCPDGYICLKTSDNPDFNYTSFDSFAWAFLSLFRLMTQDSWERLYQQTLRTSGKIYMIFFVLVIFLGSFYLVNLILAVVTMAYEEQNQATTDEIEAKEKKFQEALEMLRKEQEVLAALGIDTTSLHSHNGSPLTSKNASERRHRIKPRVSEGSTEDNKSPRSDPYNQRRMSFLGLASGKRRASHGSVFHFRSPGRDISLPEGVTDDGVFPGDHESHRGSLLLGGGAGQQGPLPRSPLPQPSNPDSRHGEDEHQPPPTSELAPGAVDVSAFDAGQKKTFLSAEYLDEPFRAQRAMSVVSIITSVLEELEESEQKCPPCLTSLSQKYLIWDCCPMWVKLKTILFGLVTDPFAELTITLCIVVNTIFMAMEHHGMSPTFEAMLQIGNIVFTIFFTAEMVFKIIAFDPYYYFQKKWNIFDCIIVTVSLLELGVAKKGSLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTIILAIIVFVFALVGKQLLGENYRNNRKNISAPHEDWPRWHMHDFFHSFLIVFRILCGEWIENMWACMEVGQKSICLILFLTVMVLGNLVVLNLFIALLLNSFSADNLTAPEDDGEVNNLQVALARIQVFGHRTKQALCSFFSRSCPFPQPKAEPELVVKLPLSSSKAENHIAANTARGSSGGLQAPRGPRDEHSDFIANPTVWVSVPIAEGESDLDDLEDDGGEDAQSFQQEVIPKGQQEQLQQVERCGDHLTPRSPGTGTSSEDLAPSLGETWKDESVPQVPAEGVDDTSSSEGSTVDCLDPEEILRKIPELADDLEEPDDCFTEGCIRHCPCCKLDTTKSPWDVGWQVRKTCYRIVEHSWFESFIIFMILLSSGSLAFEDYYLDQKPTVKALLEYTDRVFTFIFVFEMLLKWVAYGFKKYFTNAWCWLDFLIVNISLISLTAKILEYSEVAPIKALRTLRALRPLRALSRFEGMRVVVDALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFWRCINYTDGEFSLVPLSIVNNKSDCKIQNSTGSFFWVNVKVNFDNVAMGYLALLQVATFKGWMDIMYAAVDSREVNMQPKWEDNVYMYLYFVIFIIFGGFFTLNLFVGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKFQGFVFDIVTRQAFDITIMVLICLNMITMMVETDDQSEEKTKILGKINQFFVAVFTGECVMKMFALRQYYFTNGWNVFDFIVVVLSIASLIFSAILKSLQSYFSPTLFRVIRLARIGRILRLIRAAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSSFPHVRWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPNLPNSNGTRGDCGSPAVGIIFFTTYIIISFLIMVNMYIAVILENFNVATEESTEPLSEDDFDMFYETWEKFDPEATQFITFSALSDFADTLSGPLRIPKPNRNILIQMDLPLVPGDKIHCLDILFAFTKNVLGESGELDSLKANMEEKFMATNLSKSSYEPIATTLRWKQEDISATVIQKAYRSYVLHRSMALSNTPCVPRAEEEAASLPDEGFVAFTANENCVLPDKSETASATSFPPSYESVTRGLSDRVNMRTSSSIQNEDEATSMELIAPGP
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Homologous gene and protein info.
SpeciesGene IDGene Symbol이름 세금 IDOther Gene IDSources
Chimp460274SCN10Asodium voltage-gated channel alpha subunit 109598VGNC:12180OMA, EggNOG
Macaque694962SCN10Asodium voltage-gated channel alpha subunit 109544Inparanoid, OMA, EggNOG
Mouse20264Scn10asodium channel, voltage-gated, type X, alpha10090MGI:108029Inparanoid, OMA, EggNOG
Rat29571Scn10asodium voltage-gated channel alpha subunit 1010116RGD:3629Inparanoid, OMA, EggNOG
Dog477026SCN10Asodium voltage-gated channel alpha subunit 109615VGNC:45913Inparanoid, OMA, EggNOG
Horse100055493SCN10Asodium voltage-gated channel alpha subunit 109796VGNC:22730Inparanoid, OMA, EggNOG
Cow100299477SCN10Asodium voltage-gated channel alpha subunit 109913VGNC:34343Inparanoid, OMA, EggNOG
Pig100518274SCN10Asodium voltage-gated channel alpha subunit 109823OMA, EggNOG
Opossum100020766SCN10Asodium voltage-gated channel alpha subunit 1013616Inparanoid, OMA, EggNOG
Anole lizard100560187LOC100560187sodium channel protein type 5 subunit alpha28377OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    calcium channel    /    Sodium channel protein type 10 subunit alpha
protein    /    transporter    /    voltage-gated sodium channel    /    Sodium channel protein type 10 subunit alpha
protein    /    transporter    /    voltage-gated calcium channel    /    Sodium channel protein type 10 subunit alpha
protein    /    transporter    /    sodium channel    /    Sodium channel protein type 10 subunit alpha
protein    /    transporter    /    voltage-gated ion channel    /    Sodium channel protein type 10 subunit alpha
DTO Classes
protein    /    Ion channel    /    Sodium channel family    /    Nav1.8/SCN10A subfamily    /    Sodium channel protein type 10 subunit alpha

Associated Recombinant Proteins

이름 Specification and purityExpression systemProtein label재고상태자세히 보기

Associated Antibodies

이름 SpecificationsSpecies reactivity적용재고상태자세히 보기

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      이름 Direct Associated TargetsDisease TypeMondoid

      Bibliography

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