TLR2 Mouse mAb - 1차 항체, specific to TLR2, Mouse IgG1

Cat. No.: Ab131480

GRADE & PURITY Carrier Free, Validated, ExactAb™, High Performance, See COA

Application

WB

Host species

마우스

Reactive species

인간

Isotype

Mouse IgG1

Clone Number

C9

Conjugation

Unconjugated

개요

Mouse anti Human TLR2 Antibody, Monoclonal (C9), could be used for WB and so on. Application WB: 0.01-2 µg/mL

Protein Function

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Specifications

Product Name

TLR2 Mouse mAb - 1차 항체, specific to TLR2, Mouse IgG1

동의어

CD282 antibody | CD282 antigen antibody | TIL 4 antibody | TIL4 antibody | TLR 2 antibody | TLR2 antibody | TLR2_HUMAN antibody | Toll like receptor 2 antibody | Toll like receptor 2 precursor antibody | Toll-like receptor 2 antibody | Toll/interleukin 1

사양 및 순도

Carrier Free, ExactAb™, Validated, High Performance, See COA

숙주 종

마우스

특이성

TLR2

면역원

Recombinant TLR2 expressed in E.coli (AA 47-245)

포지티브 제어

WB: Human milk lysate.

변화

Unconjugated

등급

Carrier Free, ExactAb™, High Performance, Validated

아이소타입

Mouse IgG1

라이트 체인 유형

kappa

SDS-PAGE

150 kDa

정화 방법

Protein A + Protein G purified

집중력

See COA

보관 및 배송

모양

Liquid

보관 조건

Store at -20°C,Avoid repeated freezing and thawing

배송

Ice chest + Ice pads

안정성 및 스토리지

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

이미지

Western Blot: TLR2 Mouse mAb (Ab131480)

TLR2 Mouse mAb (Ab131480) - Western Blot
All lanes: TLR2 Mouse mAb (Ab131480) at 1/1000 dilution
Samples: Lysates at 20 µL per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/10000 dilution

Predicted band size: 90 kDa
Observed band size: 92 kDa
Exposure time: 95.6 s

적용

• 적용: Dilution info
• WB:

  0.01-2 µg/mL ;

관련 대상(인간)

TLR2 Tchem Toll-like receptor 2 (0 Activities)

Discover Target: TLR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TLR2 Tchem Toll-like receptor 2 (975 Activities)

Discover Target: TLR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TLR2 Tchem TLR2/TLR6 (50 Activities)

Discover Target: TLR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

자주 묻는 질문

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (TLR2 Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.