Tofersen - ≥95% , CAS No.2088232-70-4

CAS: 2088232-70-4 Cat. No.: T651797 분자량: 7128.00

등급 & 순도 ≥95%

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

개요

Tofersen (BIIB067) is an antisense oligonucleotide that mediates RNase H-dependent degradation of superoxide dismutase 1 (SOD1) mRNA to reduce the synthesis of SOD1 protein. Tofersen can be used for the research of amyotrophic lateral sclerosis (ALS).

In Vitro

Tofersen targets the SOD1 mRNA using antisense oligonucleotides (ASOs) that bind to the SOD1 mRNA by Watson-Crick base pairing. Tofersen activates RNase H1 that destroys the targeted RNA. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

사양

사양 및 순도

≥95%

생화학 및 생리적 메커니즘

Tofersen (BIIB067) is an antisense oligonucleotide that mediates RNase H-dependent degradation of superoxide dismutase 1 (SOD1) mRNA to reduce the synthesis of SOD1 protein. Tofersen can be used for the research of amyotrophic lateral sclerosis (ALS)

보관 조건

Store at -20°C,Argon charged,Desiccated

배송

Ice chest + Ice pads

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순수함

≥95%

이름과 식별자

정식 스마일

[Tofersen]

분자량

7128.00

화학 및 물리적 특성

• 용해성: H2O : 100 mg/mL (14.03 mM; Need ultrasonic)

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, desiccated, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2088232-70-4, and the molecular weight is 7128.00 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.