TQS - ≥98%(HPLC) , CAS No.353483-92-8

CAS: 353483-92-8 Cat. No.: T286911 분자식: C22H20N2O2S 분자량: 376.47 PubChem CID: 5038679
주문 가능
GRADE & PURITY ≥98%(HPLC)
Synonyms
3a,4,5,9b-Tetrahydro-4-(1-naphthalenyl)-3H-cyclopentan[c]quinoline-8-sulfonamide | 4-(naphthalen-1-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
USA
독일 (EU)*
Price
Qty
5mg
T286911-5mg
3 재고 있음
—
US$93.90
10mg
T286911-10mg
3 재고 있음
—
US$147.90
25mg
T286911-25mg
3 재고 있음
—

US$265.90

US$315.90
저장 US$50.00 (15.83%)
50mg
T286911-50mg
주문제작 · 8~12주

US$424.90

US$513.90
저장 US$89.00 (17.32%)
100mg
T286911-100mg
2 재고 있음
—

US$679.90

US$840.90
저장 US$161.00 (19.15%)
250mg
T286911-250mg
주문제작 · 8~12주

US$1,358.90

US$1,892.90
저장 US$534.00 (28.21%)
Enter a quantity for the sizes you want to add.
🧪
Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

동의어
3a,4,5,9b-Tetrahydro-4-(1-naphthalenyl)-3H-cyclopentan[c]quinoline-8-sulfonamide | 4-(naphthalen-1-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
사양 및 순도
≥98%(HPLC)
생화학 및 생리적 메커니즘
Type II positive allosteric modulator ofα7 nACh receptors (pEC50= 5.5). Displays no agonist activity atα7 receptors at concentrations up to 0.1 mM; potentiates agonist-evoked responses and reduces rate of desensitization ofα7 nAChRs. Exhibits potency and
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
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순수함
≥98%(HPLC)
이름과 식별자
Pubchem Sid
정식 스마일
C1C=CC2C1C(NC3=C2C=C(C=C3)S(=O)(=O)N)C4=CC=CC5=CC=CC=C54
IUPAC Name
4-naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
InChIKey
SIZWDJIHABLBSP-UHFFFAOYSA-N
INCHI
1S/C22H20N2O2S/c23-27(25,26)15-11-12-21-20(13-15)17-8-4-10-19(17)22(24-21)18-9-3-6-14-5-1-2-7-16(14)18/h1-9,11-13,17,19,22,24H,10H2,(H2,23,25,26)
이성체 SMILES
C1C=CC2C1C(NC3=C2C=C(C=C3)S(=O)(=O)N)C4=CC=CC5=CC=CC=C54
PubChem CID
5038679
분자량
376.47

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
분류Quinolines and derivatives
SubclassHydroquinolines
Intermediate Tree Nodes Not available
Direct ParentHydroquinolines
Alternative Parents Naphthalenes  Secondary alkylarylamines  Aralkylamines  Organosulfonamides  Aminosulfonyl compounds  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Tetrahydroquinoline - Naphthalene - Secondary aliphatic/aromatic amine - Aralkylamine - Organosulfonic acid amide - Benzenoid - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Aminosulfonyl compound - Sulfonyl - Secondary amine - Azacycle - Organic oxide - Amine - Organopnictogen compound - Organosulfur compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
설명This compound belongs to the class of organic compounds known as hydroquinolines. These are derivatives of quinoline in which in which at least one double bond in the quinoline moiety are reduced by adding two hydrogen atoms.
External Descriptors Not available
3D 구조
상호 작용 화학 구조 모델





관련 대상(인간)
CHRNA7 Tchem Neuronal acetylcholine receptor subunit alpha-7 (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRNA7 Tchem Neuronal acetylcholine receptor protein alpha-7 subunit (3524 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate Type날짜항목
B2603037Certificate of AnalysisFeb 25, 2026 T286911
B2603036Certificate of AnalysisFeb 25, 2026 T286911
K2108425Certificate of AnalysisAug 20, 2024 T286911
K2108426Certificate of AnalysisAug 20, 2024 T286911
K2108429Certificate of AnalysisAug 20, 2024 T286911
K2108788Certificate of AnalysisAug 20, 2024 T286911
K2108789Certificate of AnalysisAug 20, 2024 T286911
K2108790Certificate of AnalysisAug 20, 2024 T286911
화학 및 물리적 특성
용해성Solvent:DMSO, Max Conc. mg/mL: 18.82, Max Conc. mM: 50
분자량376.500 g/mol
XLogP34.200
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass376.125 Da
Monoisotopic Mass376.125 Da
Topological Polar Surface Area80.600 Ų
Heavy Atom Count27
Formal Charge0
Complexity685.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count3
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
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