UCLA GP130 2 - ≥98%(HPLC) , CAS No.339303-87-6

CAS: 339303-87-6 Cat. No.: U287103 분자식: C₁₅H₁₁FN₂S 분자량: 270.32 PubChem CID: 623055

GRADE & PURITY ≥98%(HPLC)

Synonyms

N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

동의어

N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine

사양 및 순도

≥98%(HPLC)

생화학 및 생리적 메커니즘

gp130 agonist. Protects against NMDA-induced toxicity in primary hippocampal neuronsin vitro. Increases STAT3 phosphorylation in SH-SY5Y cells. Brain penetrant.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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순수함

≥98%(HPLC)

이름과 식별자

• Pubchem Sid: 504759579
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504759579
• 정식 스마일: C1=CC=C(C=C1)C2=CSC(=N2)NC3=CC=C(C=C3)F
• IUPAC Name: N-(4-fluorophenyl)-4-phenyl-1,3-thiazol-2-amine
• InChIKey: RSKMQDIAPGOWDL-UHFFFAOYSA-N
• INCHI: 1S/C15H11FN2S/c16-12-6-8-13(9-7-12)17-15-18-14(10-19-15)11-4-2-1-3-5-11/h1-10H,(H,17,18)
• 이성체 SMILES: C1=CC=C(C=C1)C2=CSC(=N2)NC3=CC=C(C=C3)F
• PubChem CID: 623055
• 분자량: 270.32

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • 분류 Benzene and substituted derivatives
      • Subclass Aniline and substituted anilines

• Kingdom: Organic compounds
• Superclass: Benzenoids
• 분류: Benzene and substituted derivatives
• Subclass: Aniline and substituted anilines
• Intermediate Tree Nodes: Not available
• Direct Parent: Aniline and substituted anilines
• Alternative Parents: Fluorobenzenes 2,4-disubstituted thiazoles Aryl fluorides 2-amino-1,3-thiazoles Heteroaromatic compounds Secondary amines Azacyclic compounds Organopnictogen compounds Organofluorides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Aniline or substituted anilines - 2,4-disubstituted 1,3-thiazole - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - 1,3-thiazol-2-amine - Azole - Heteroaromatic compound - Thiazole - Azacycle - Secondary amine - Organoheterocyclic compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Amine - Organic nitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Aromatic heteromonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as aniline and substituted anilines. These are organic compounds containing an aminobenzene moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(비인간)

Leishmania donovani (89745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 용해성: Solvent:DMSO, Max Conc. mg/mL: 27.03, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 27.03, Max Conc. mM: 100
• 분자량: 270.300 g/mol
• XLogP3: 4.600
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 270.063 Da
• Monoisotopic Mass: 270.063 Da
• Topological Polar Surface Area: 53.200 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 275.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 339303-87-6, the molecular formula is C15H11FN2S, and the molecular weight is 270.32 g/mol. InChIKey RSKMQDIAPGOWDL-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.