URB 937 - Moligand™, ≥98% , Inhibitor of Fatty acid amide hydrolase, CAS No.1357160-72-5, Inhibitor of Fatty acid amide hydrolase

CAS: 1357160-72-5 Cat. No.: U351248 분자식: C₂₀H₂₂N₂O₄ 분자량: 354.4 EC 번호: 802-936-2 PubChem CID: 53394762

GRADE & PURITY Moligand™, ≥98%

Synonyms

cyclohexylcarbamic acid 3'-carbamoyl-6-hydroxybiphenyl-3-yl ester | DTXSID801018151 | BDBM50437227 | MS-25529 | [3-(3-carbamoylphenyl)-4-hydroxyphenyl] N-cyclohexylcarbamate | 3'-(Aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl N-cyclohexylcarbamate | AC-365

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Product description

URB937 is an orally active and peripherally restricted FAAH inhibitor (IC50=26.8 nM) and increases anandamide levels. URB937 fails to affect FAAH activity in the brain (not penetrate the blood-brain barrier).

Specifications

동의어

cyclohexylcarbamic acid 3'-carbamoyl-6-hydroxybiphenyl-3-yl ester | DTXSID801018151 | BDBM50437227 | MS-25529 | [3-(3-carbamoylphenyl)-4-hydroxyphenyl] N-cyclohexylcarbamate | 3'-(Aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl N-cyclohexylcarbamate | AC-365

사양 및 순도

Moligand™, ≥98%

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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등급

Moligand™

작업 유형

INHIBITOR

작동 메커니즘

Inhibitor of Fatty acid amide hydrolase

순수함

≥98%

이름과 식별자

• Pubchem Sid: 504771192
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504771192
• 정식 스마일: C1CCC(CC1)NC(=O)OC2=CC(=C(C=C2)O)C3=CC(=CC=C3)C(=O)N
• IUPAC Name: [3-(3-carbamoylphenyl)-4-hydroxyphenyl] N-cyclohexylcarbamate
• InChIKey: CMEQHOXCIGFZNJ-UHFFFAOYSA-N
• INCHI: 1S/C20H22N2O4/c21-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)23)26-20(25)22-15-7-2-1-3-8-15/h4-6,9-12,15,23H,1-3,7-8H2,(H2,21,24)(H,22,25)
• 이성체 SMILES: C1CCC(CC1)NC(=O)OC2=CC(=C(C=C2)O)C3=CC(=CC=C3)C(=O)N
• WGK 독일: 3
• PubChem CID: 53394762
• 분자량: 354.4

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • 분류 Benzene and substituted derivatives
      • Subclass Biphenyls and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• 분류: Benzene and substituted derivatives
• Subclass: Biphenyls and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Biphenyls and derivatives
• Alternative Parents: Benzamides Phenoxy compounds Benzoyl derivatives 1-hydroxy-2-unsubstituted benzenoids Carbamate esters Primary carboxylic acid amides Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Biphenyl - Benzamide - Benzoic acid or derivatives - Phenoxy compound - Benzoyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Carbamic acid ester - Primary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Aromatic homomonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

FAAH Tchem Fatty-acid amide hydrolase 1 (0 Activities)

Discover Target: FAAH

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

관련 대상(비인간)

Faah Anandamide amidohydrolase (3907 Activities)

Discover Target: Faah

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 분자량: 354.400 g/mol
• XLogP3: 3.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 354.158 Da
• Monoisotopic Mass: 354.158 Da
• Topological Polar Surface Area: 102.000 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 492.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1357160-72-5, the molecular formula is C20H22N2O4, and the molecular weight is 354.4 g/mol. InChIKey CMEQHOXCIGFZNJ-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.