Valproic acid-d15 - ≥99%,≥99 atom% D , CAS No.362049-65-8

CAS: 362049-65-8 Cat. No.: V650220 분자식: C₈HD₁₅O₂ 분자량: 159.30

GRADE & PURITY ≥99%,≥99 atom% D

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Valproic acid-d15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

Specifications

사양 및 순도

≥99%,≥99 atom% D

생화학 및 생리적 메커니즘

Valproic acid-d 15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor , with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2 . Valpro

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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작업 유형

INHIBITOR

순수함

≥99%,≥99 atom% D

이름과 식별자

• Pubchem Sid: 528767684
• 이성체 SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])(C(=O)O)C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
• 대체 CAS: 99-66-1(unlabelled)
• 분자량: 159.30