Vitronectin from Human Plasma, CAS No.83380-82-9

CAS: 83380-82-9 Cat. No.: np001007

GRADE & PURITY BioReagent, Native, PBS Only, ≥95%(SDS-PAGE), See COA

Accession #

P04004

Overview

 Vitronectin and plasminogen activator inhibitor type 1 are proteins that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration. Plasminogen activator inhibitor type 1, a serine proteinase, through its binding to the plasma protein vitronectin, influences processes that are key regulators of hemostatic process, for example, thrombosis and wound healing. In addition the vitronectin and plasminogen activator inhibitor type 1 complex regulates binding of blood platelets and cells to extracellular substrata in events like tumor metastasis. The plasma concentration of vitronectin is 200 to 400 μg/ml.
Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.
Aladdin products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.

Specifications

Product Name

Vitronectin from Human Plasma, CAS No.83380-82-9

Synonyms

Complement S Protein | Epibolin | S Protein | S-protein | Serum Spreading Factor | Serum-spreading factor | Somatomedin B | Somatomedin-B | V75 | Vitronectin | Vitronectin V10 subunit | Vitronectin V65 subunit | VN | VNT | VTN | VTNC_HUMAN

Grade

BioReagent, Native, PBS Only

Specifications & Purity

BioReagent, Native, PBS Only, ≥95%(SDS-PAGE), See COA

Biochemical and Physiological Mechanisms

Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. In

Accession #

P04004

Predicted molecular weight

65 kDa,  75 kDa

CAS

83380-82-9

Molecule Type

Protein

Storage and Shipping

Shape

Lyophilized from 10 mM sodium phosphate, pH 7.7

Concentration

See COA

Reconstitution

After centrifugation, we suggest addition of de-ionized H2O to the original volume (See COA), followed by gentle mixingto ensure adequate homogenization. If further dilution is required, please use the lyophilization buffer.

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Stability And Storage

Store at -20℃ long term (>1 year). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.