Azido-PEG4-NHS Ester - ≥95% , CAS No.944251-24-5

CAS: 944251-24-5 Cat. No.: A305020 Molecular Weight: 388.37

GRADE & PURITY ≥95%

Synonyms

N3-PEG4-C2-NHS ester | 3-(Azidotetra(ethyleneoxy))propionic acid succinimidyl ester | NHS-Peg4-Azide | Polyethylene glycol | Azido-dPEG®4-NHS ester | 15-Azido-4,7,10,13-tetraoxapentadecanoate | 15-Azido-4,7,10,13-tetraoxapentadecanoic Acid N-Succinimidyl

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

Antibody Drug Conjugates(ADC), Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

Specifications

Synonyms

N3-PEG4-C2-NHS ester | 3-(Azidotetra(ethyleneoxy))propionic acid succinimidyl ester | NHS-Peg4-Azide | Polyethylene glycol | Azido-dPEG®4-NHS ester | 15-Azido-4, 7, 10, 13-tetraoxapentadecanoate | 15-Azido-4, 7, 10, 13-tetraoxapentadecanoic Acid N-Succinimidyl

Specifications & Purity

≥95%

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Canonical Smiles: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCN=[N+]=[N-]
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoate
• InChIKey: OIGKWPIMJCPGGD-UHFFFAOYSA-N
• INCHI: 1S/C15H24N4O8/c16-18-17-4-6-24-8-10-26-12-11-25-9-7-23-5-3-15(22)27-19-13(20)1-2-14(19)21/h1-12H2
• Isomeric SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCN=[N+]=[N-]
• Molecular Weight: 388.37
• Reaxy-Rn: 15516834
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=15516834&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Pyrrolidines
      • Subclass Pyrrolidones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Pyrrolidines
• Subclass: Pyrrolidones
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrrolidine-2-ones
• Alternative Parents: Dicarboximides Lactams Azo imides Azo compounds Monocarboxylic acids and derivatives Dialkyl ethers Azacyclic compounds Organic zwitterions Organic salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: 2-pyrrolidone - Dicarboximide - Azo compound - Azo imide - Lactam - Carboxylic acid derivative - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Azacycle - Carbonyl group - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Organic zwitterion - Organic salt - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines which bear a C=O group at position 2 of the pyrrolidine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Moisture Sensitive；Heat Sensitive
• Molecular Weight: 388.370 g/mol
• XLogP3: -0.500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 17
• Exact Mass: 388.159 Da
• Monoisotopic Mass: 388.159 Da
• Topological Polar Surface Area: 115.000 Ų
• Heavy Atom Count: 27
• Formal Charge: 0
• Complexity: 508.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Fang Dong, Liangwen Hao, Lin Wang, Ying Huang.  (2024)  Clickable nanozyme enhances precise colonization of probiotics for ameliorating inflammatory bowel disease.  JOURNAL OF CONTROLLED RELEASE,      [PMID:39084465] [10.1016/j.jconrel.2024.07.064]

2. Xuena Zhu, Shanshan Wang, Yuanyuan Xue, Xiaoyan Wang, Shaoqi Hu, Tingbo Liang, Wenjun Liu.  (2025)  Coupling CRISPR-Cas and a personal glucose meter with an enzymatic reporter for portable detection of human papillomavirus in biological samples.  Theranostics,  15  (7): (2870).  [PMID:40083940] [10.7150/thno.106490]

3. Haorui Cao, Kang Mao, Jiajia Yang, Qingqing Wu, Jiming Hu, Hua Zhang.  (2024)  High-Throughput μPAD with Cascade Signal Amplification through Dual Enzymes for arsM in Paddy Soil.  ANALYTICAL CHEMISTRY,      [PMID:38613479] [10.1021/acs.analchem.3c05958]

4. Xuan Wu, Rong Xiang, Danting Yang, Xiaoyao He, Lu Zhu, Fangfang Sun, Hanqing Li, Ningning Pi, Yi Li.  (2024)  HRP-integrated CRISPR-Cas12a biosensor for rapid point-of-care detection of Langya henipavirus.  iScience,      [PMID:39758988] [10.1016/j.isci.2024.111466]

5. Yumin Liu, Kunming Xing, Yuyan Li, Kexin Liu, Guangyao Tan, Shusheng Zhang, Pengfei Shi, Yingnan Sun.  (2025)  Dual-Stage Propulsion Strategy for Microalgae-Based Biohybrid Microrobots.  ACS Applied Materials & Interfaces,      [PMID:40461413] [10.1021/acsami.5c09537]