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224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items

Caspase-1 Mouse mAb - Primary antibody, specific to Caspase-1, Mouse IgG2b

Cat. No.: Ab183885
COA
Caspase-1 Mouse mAb - by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE) 1.0 mg/mL
Application
WB
Host species
Mouse
Reactive species
Human
Isotype
Mouse IgG2b
Clone Number
AB01/3H8
Conjugation
Unconjugated
★
Size
USA
Germany (EU)*
Price
Qty
10μl
Ab183885-10μl
5 In stock
—
$99.90
50μl
Ab183885-50μl
4 In stock
—
$259.90
100μl
Ab183885-100μl
1 In stock
—
$419.90
1ml
Ab183885-1ml
US Made to order · 2–4 wks ·
—
$3,399.90
Enter a quantity for the sizes you want to add.
Bulk / Custom
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Storage and Shipping Images Application Documentation Advanced Data Associated Targets(Human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Documents & Articles Solution Calculators Reviews
🧪

Why this grade

Carrier Free,ExactAb™,Azide Free,Validated,High Performance,PBS Only,≥95%(SDS-PAGE),1.0 mg/mL Azide Free,Carrier Free,ExactAb™,High Performance,PBS Only,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Application
WB: 1/1,000 – 1/2,000. Predicted molecular weight: 45.2 KDa

Specifications

Product Name
Caspase-1 Mouse mAb - Primary antibody, specific to Caspase-1, Mouse IgG2b
Synonyms
CASP-1 antibody | CASP1 antibody | CASP1_HUMAN antibody | Caspase 1 antibody | Caspase-1 subunit p10 antibody | ICE antibody | IL-1 beta-converting enzyme antibody | IL-1BC antibody | IL1 beta converting enzyme antibody | IL1B convertase antibody | Interl
Specifications & Purity
Carrier Free, ExactAb™, Azide Free, Validated, High Performance, PBS Only, ≥95%(SDS-PAGE), 1.0 mg/mL
Host species
Mouse
Specificity
Caspase-1
Immunogen
Recombinant protein corresponding to Human Caspase-1
Positive Control
WB: THP-1 and A431 whole cell lysates
Conjugation
Unconjugated
Grade
Azide Free, Carrier Free, ExactAb™, High Performance, PBS Only, Validated
Isotype
Mouse IgG2b
Light Chain Type
kappa
SDS-PAGE
150.0 KDa
Purification Method
Protein A purified
Concentration
1.0 mg/mL
Storage and Shipping
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Images

Caspase-1 Mouse mAb (Ab183885) - Western Blot
All lanes: Caspase-1 Mouse Antibody (Ab183885) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 45 kDa
Observed band size: 46 kDa
Exposure time: 60.0 s

Application
ApplicationDilution info
WB

1/1,000 – 1/2,000. Predicted molecular weight: 45.2 KDa

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
CASP1 Tchem Caspase-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0809689Certificate of AnalysisJun 22, 2026 Ab183885
ZJ24F0809690Certificate of AnalysisJun 22, 2026 Ab183885
Documents & Articles
Protocol of Western Blotting For High Molecular Weights
Categories: Laboratory Protocols & SOPs Library
Tags:
Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody
Apoptosis Induction Methods
Categories: Laboratory Protocols & SOPs Library
Tags:
Apoptosis Programmed Death Caspase Apoptosis induction Chemical induction Biological induction Apoptosis factor Fas CD95
Purine Metabolism Disorders and Hyperuricemia Research: Metabolic Pathways, Key Enzymes, and Detection Indicators
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
purine metabolism hyperuricemia uric acid detection xanthine oxidase urate crystals uric acid transport gout inflammation
How to Detect Cholinergic Indicators in Alzheimer’s Disease Models? Integrated Analysis of Acetylcholine, AChE, and Inflammatory Factors
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
neuroinflammation Acetylcholinesterase ChAT IL-1β TNF-α IL-6 AChE activity Acetylcholine Detection Choline Acetyltransferase Microglia Hippocampus Cortex
Four Major Classifications and Seven Key Mechanisms of Neuroinflammation
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
Neurodegenerative diseases neuroinflammation inflammasome blood-brain barrier Microglia Acute Neuroinflammation Chronic Neuroinflammation Primary Neuroinflammation Secondary Neuroinflammation Astrocytes
Construction, Characterization, and Neurological Disease Modeling of Microglia-Containing Brain Organoids
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
Parkinson’S Disease Modeling neuroinflammation Microglia induced pluripotent stem cells three-dimensional culture brain organoids MC-HBOs
Autoantigens, Core Signaling Pathways, and Organ Damage Mechanisms in Systemic Lupus Erythematosus
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
Complement BAFF B cells Systemic Lupus Erythematosus Autoantigens Type I Interferons Immune Complexes Lupus Nephritis
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Carrier Free grade guide → View Validated grade guide → View ExactAb™ grade guide → View Azide Free grade guide → View High Performance grade guide → View PBS Only grade guide →
Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

View related series

Click to view target information: CASP1
 Accession#:P29466 (5) CASP1 (4) Caspase-1 (1) Gene ID:834 (4)

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