CDK

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  1. Senexin A
    CAS: 1366002-50-7 EC Number: 878-626-6 PubChem CID: 56927063 Formula: C17H14N4
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: S421393
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    IUPAC Name
    4-(2-phenylethylamino)quinazoline-6-carbonitrile
    SMILES
    C1=CC=C(C=C1)CCNC2=NC=NC3=C2C=C(C=C3)C#N
    InChIKey
    XBJCNHGQFJFCOY-UHFFFAOYSA-N
    InChI
    1S/C17H14N4/c18-11-14-6-7-16-15(10-14)17(21-12-20-16)19-9-8-13-4-2-1-3-5-13/h1-7,10,12H,8-9H2,(H,19,20,21)
    Synonyms
    BCP25089 | AC-33659 | AKOS028113542 | SCHEMBL16172718 | 1366002-50-7 | CCG-267196 | 4-(Phenethylamino)quinazoline-6-c...
  2. TG 003
    CAS: 719277-26-6 PubChem CID: 1893668 Formula: C13H15NO2S Molecular Weight: 249.33
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: T425649
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    IUPAC Name
    (1Z)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one
    SMILES
    CCN1C2=C(C=CC(=C2)OC)SC1=CC(=O)C
    InChIKey
    BGVLELSCIHASRV-QPEQYQDCSA-N
    InChI
    1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3/b13-7-
    Synonyms
    TG003|TG-003|719277-26-6|300801-52-9|(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one|KPC5K8BP...
  3. TC11
    CAS: 100823-03-8 PubChem CID: 1235479 Formula: C20H22N2O2 Molecular Weight: 322.40
    ● In Stock — US warehouse, ships to EU* Item #: T413516
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    IUPAC Name
    5-amino-2-[2,6-di(propan-2-yl)phenyl]isoindole-1,3-dione
    SMILES
    CC(C)C1=C(C(=CC=C1)C(C)C)N2C(=O)C3=C(C2=O)C=C(C=C3)N
    InChIKey
    NRPIRIUWEKTNGQ-UHFFFAOYSA-N
    InChI
    1S/C20H22N2O2/c1-11(2)14-6-5-7-15(12(3)4)18(14)22-19(23)16-9-8-13(21)10-17(16)20(22)24/h5-12H,21H2,1-4H3
    Synonyms
    TC11 | CS-0105753 | 5-amino-2-[2,6-di(propan-2-yl)phenyl]isoindole-1,3-dione | HY-129478 | SCHEMBL2818285 | 5-Amino-2...
  4. THZ1, Inhibitor of cyclin dependent kinase 7
    CAS: 1604810-83-4 PubChem CID: 73602827 Formula: C31H28ClN7O2 Molecular Weight: 566.05
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ● In Stock — US warehouse, ships to EU* Item #: T413778
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    IUPAC Name
    N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamide
    SMILES
    CN(C)CC=CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
    InChIKey
    OBJNFLYHUXWUPF-IZZDOVSWSA-N
    InChI
    1S/C31H28ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-1show more
    Synonyms
    N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamide | ...
  5. THZ2
    CAS: 1604810-84-5 PubChem CID: 78357763 Formula: C31H28ClN7O2 Molecular Weight: 566.05
    ● In Stock — US warehouse, ships to EU* Item #: T413894
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    IUPAC Name
    N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamide
    SMILES
    CN(C)CC=CC(=O)NC1=CC=CC(=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
    InChIKey
    FONRCZUZCHXWBD-VGOFMYFVSA-N
    InChI
    1S/C31H28ClN7O2/c1-39(2)15-7-14-28(40)35-21-9-5-8-20(16-21)30(41)36-22-10-6-11-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-13-4-3-12-24(25)27/h3-1show more
    Synonyms
    (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-3-(4-(dimethylamino)but-2-enamido)benzamide | BS-15...
  6. THZ2
    CAS: 1604810-84-5 PubChem CID: 78357763 Formula: C31H28ClN7O2 Molecular Weight: 566.05
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: T421923
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    Technical Identifiers
    IUPAC Name
    N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamide
    SMILES
    CN(C)CC=CC(=O)NC1=CC=CC(=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
    InChIKey
    FONRCZUZCHXWBD-VGOFMYFVSA-N
    InChI
    1S/C31H28ClN7O2/c1-39(2)15-7-14-28(40)35-21-9-5-8-20(16-21)30(41)36-22-10-6-11-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-13-4-3-12-24(25)27/h3-1show more
    Synonyms
    (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-3-(4-(dimethylamino)but-2-enamido)benzamide | BS-15...
  7. THZ531
    CAS: 1702809-17-3 EC Number: 959-488-7 PubChem CID: 118025540 Formula: C30H32ClN7O2 Molecular Weight: 558.07
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: T422100
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    IUPAC Name
    (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidine-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide
    SMILES
    CN(C)CC=CC(=O)NC1=CC=C(C=C1)C(=O)N2CCCC(C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
    InChIKey
    RUBYHLPRZRMTJO-MOVYNIQHSA-N
    InChI
    1S/C30H32ClN7O2/c1-37(2)15-6-10-27(39)34-21-13-11-20(12-14-21)29(40)38-16-5-7-22(19-38)35-30-33-18-25(31)28(36-30)24-17-32-26-9-4-3-8-23(24)26/h3-4,6,show more
    Synonyms
    2-​Butenamide,N-​[4-​[[(3R)​-​3-​[[5-​chloro-​4-​(1H-​indol-​3-​yl)​-​2-​pyrimidinyl]​amino]​-​1-​piperidinyl]​carbon...
  8. THZ531
    CAS: 1702809-17-3 EC Number: 959-488-7 PubChem CID: 118025540 Formula: C30H32ClN7O2 Molecular Weight: 558.07
    ● In Stock — US warehouse, ships to EU* Item #: T413537
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    Technical Identifiers
    IUPAC Name
    (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidine-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide
    SMILES
    CN(C)CC=CC(=O)NC1=CC=C(C=C1)C(=O)N2CCCC(C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
    InChIKey
    RUBYHLPRZRMTJO-MOVYNIQHSA-N
    InChI
    1S/C30H32ClN7O2/c1-37(2)15-6-10-27(39)34-21-13-11-20(12-14-21)29(40)38-16-5-7-22(19-38)35-30-33-18-25(31)28(36-30)24-17-32-26-9-4-3-8-23(24)26/h3-4,6,show more
    Synonyms
    2-​Butenamide,N-​[4-​[[(3R)​-​3-​[[5-​chloro-​4-​(1H-​indol-​3-​yl)​-​2-​pyrimidinyl]​amino]​-​1-​piperidinyl]​carbon...
  9. TG003, Inhibitor of CDC like kinase 1;Inhibitor of CDC like kinase 2
    CAS: 300801-52-9 EC Number: 636-912-6 PubChem CID: 1893668 Formula: C13H15NO2S Molecular Weight: 249.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: Z135434
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    Technical Identifiers
    IUPAC Name
    (1Z)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one
    SMILES
    CCN1C2=C(C=CC(=C2)OC)SC1=CC(=O)C
    InChIKey
    BGVLELSCIHASRV-QPEQYQDCSA-N
    InChI
    1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3/b13-7-
    Synonyms
    SDCCGSBI-0050869.P003 | NCGC00032387-06 | SW219950-1 | BGVLELSCIHASRV-QPEQYQDCSA-N | UNII-KPC5K8BPP7 | SR-01000076048...
  10. THAL SNS 032, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 7;Inhibitor of cyclin dependent kinase 9
    CAS: 2139287-33-3 PubChem CID: 131801483 Formula: C40H52N8O10S2 Molecular Weight: 869.02
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: T422584
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    Technical Identifiers
    IUPAC Name
    N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]-1-[2-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoshow more
    SMILES
    CC(C)(C)C1=CN=C(O1)CSC2=CN=C(S2)NC(=O)C3CCN(CC3)CC(=O)NCCOCCOCCOCCNC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O
    InChIKey
    BXDZOYLPNAIDOC-UHFFFAOYSA-N
    InChI
    1S/C40H52N8O10S2/c1-40(2,3)29-21-43-32(58-29)24-59-33-22-44-39(60-33)46-35(51)25-9-13-47(14-10-25)23-31(50)42-12-16-56-18-20-57-19-17-55-15-11-41-27-6show more
    Synonyms
    N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)-1-(14-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4...
  11. Trilaciclib (G1T28), Cyclin-dependent kinase 6 inhibitor
    CAS: 1374743-00-6 PubChem CID: 68029831 Formula: C24H30N8O Molecular Weight: 446.55
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: T413997
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    Technical Identifiers
    IUPAC Name
    4-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]spiro[1,3,5,11-tetrazatricyclo[7.4.0.02,7]trideca-2,4,6,8-tetraene-13,1'-cyclohexane]-10-one
    SMILES
    CN1CCN(CC1)C2=CN=C(C=C2)NC3=NC=C4C=C5C(=O)NCC6(N5C4=N3)CCCCC6
    InChIKey
    PDGKHKMBHVFCMG-UHFFFAOYSA-N
    InChI
    1S/C24H30N8O/c1-30-9-11-31(12-10-30)18-5-6-20(25-15-18)28-23-26-14-17-13-19-22(33)27-16-24(7-3-2-4-8-24)32(19)21(17)29-23/h5-6,13-15H,2-4,7-12,16H2,1Hshow more
    Synonyms
    BCP25013 | 2'-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2'...
  12. Tyrphostin AG 494
    CAS: 133550-35-3 EC Number: 810-936-9 PubChem CID: 5328771 Formula: C16H12N2O3 Molecular Weight: 280.28
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: T421272
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    Technical Identifiers
    IUPAC Name
    (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide
    SMILES
    C1=CC=C(C=C1)NC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
    InChIKey
    HKHOVJYOELRGMV-XYOKQWHBSA-N
    InChI
    1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)/b12-8+
    Synonyms
    MKXZASYAUGDDCJ-UHFFFAOYSA-N | DTXSID201018515 | HMS3414I07 | s6509 | AKOS024458583 | HMS2232N04 | NCGC00024687-02 | B...
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Frequently Asked Questions

What can I find under CDK?
This listing collects compounds associated with CDK within our Cell Cycle/DNA Damage area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for CDK?
Consider the reported potency of each CDK compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for CDK compounds?
Each CDK product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search CDK compounds by activity or structure?
Yes. Filter the CDK listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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