CDK

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  1. ML 315 hydrochloride
    CAS: 1440251-53-5 PubChem CID: 127021037 Formula: C18H13Cl2N3O2.HCl Molecular Weight: 410.68
    ● In Stock — US warehouse, ships to EU* Item #: M288578
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    IUPAC Name
    5-(1,3-benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]pyrimidin-4-amine;hydrochloride
    SMILES
    C1OC2=C(O1)C=C(C=C2)C3=CN=CN=C3NCC4=CC(=CC(=C4)Cl)Cl.Cl
    InChIKey
    MNCDEAAKKQCKSX-UHFFFAOYSA-N
    InChI
    1S/C18H13Cl2N3O2.ClH/c19-13-3-11(4-14(20)6-13)7-22-18-15(8-21-9-23-18)12-1-2-16-17(5-12)25-10-24-16;/h1-6,8-9H,7,10H2,(H,21,22,23);1H
    Synonyms
    5-(1,3-Benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]-4-pyrimidinamine hydrochloride
  2. ML-167
    CAS: 1285702-20-6 EC Number: 808-432-9 Formula: C19H17N3O3 Molecular Weight: 335.36
    ● In Stock — US warehouse, ships to EU* Item #: M274979
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    IUPAC Name
    [5-[4-[(5-methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanol
    SMILES
    CC1=CC=C(O1)CNC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CO
    InChIKey
    ROCFOIBAEVAOLQ-UHFFFAOYSA-N
    InChI
    1S/C19H17N3O3/c1-12-2-4-14(24-12)9-20-19-16-8-13(3-6-17(16)21-11-22-19)18-7-5-15(10-23)25-18/h2-8,11,23H,9-10H2,1H3,(H,20,21,22)
    Synonyms
    NCGC00188654-04 | [5-(4-{[(5-METHYLFURAN-2-YL)METHYL]AMINO}QUINAZOLIN-6-YL)FURAN-2-YL]METHANOL | BDBM50342913 | AC-35...
  3. AT7519, Cyclin-dependent kinase inhibitor
    CAS: 844442-38-2 Formula: C16H17Cl2N5O2 Molecular Weight: 382.24
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: A127001
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    IUPAC Name
    4-[(2,6-dichlorobenzoyl)amino]-N-piperidin-4-yl-1H-pyrazole-5-carboxamide
    SMILES
    C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl
    InChIKey
    OVPNQJVDAFNBDN-UHFFFAOYSA-N
    InChI
    1S/C16H17Cl2N5O2/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9/h1-3,8-9,19H,4-7H2,(H,20,23)(H,21,25)(H,22,24)
    Synonyms
    NSC773394 | NSC-773394 | SY009677 | BDBM24654 | CCG-264904 | NSC799338 | NSC-799338 | OVPNQJVDAFNBDN-UHFFFAOYSA-N | 4...
  4. AZD5438, Cyclin-dependent kinase inhibitor
    CAS: 602306-29-6 Formula: C18H21N5O2S Molecular Weight: 371.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A126894
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    IUPAC Name
    4-(2-methyl-3-propan-2-ylimidazol-4-yl)-N-(4-methylsulfonylphenyl)pyrimidin-2-amine
    SMILES
    CC1=NC=C(N1C(C)C)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)C
    InChIKey
    WJRRGYBTGDJBFX-UHFFFAOYSA-N
    InChI
    1S/C18H21N5O2S/c1-12(2)23-13(3)20-11-17(23)16-9-10-19-18(22-16)21-14-5-7-15(8-6-14)26(4,24)25/h5-12H,1-4H3,(H,19,21,22)
    Synonyms
    Tox21_112591 | Monoiodomethanesulfonic acid, sodium salt | 4-(1-isopropyl-2-methylimidazol-5-yl)-2-(4-mesylanilino)py...
  5. Alsterpaullone, Inhibitor of cyclin dependent kinase 1;Inhibitor of glycogen synthase kinase 3 beta
    CAS: 237430-03-4 EC Number: 636-614-6 Formula: C16H11N3O3 Molecular Weight: 293.28
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A274619
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    IUPAC Name
    9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one
    SMILES
    C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)[N+](=O)[O-]
    InChIKey
    OLUKILHGKRVDCT-UHFFFAOYSA-N
    InChI
    1S/C16H11N3O3/c20-15-8-12-11-7-9(19(21)22)5-6-14(11)18-16(12)10-3-1-2-4-13(10)17-15/h1-7,18H,8H2,(H,17,20)
    Synonyms
    BDBM7262 | EX-A4771 | HMS2043P15 | 9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one | J-015199 | BRD-K1751638...
  6. Aminopurvalanol A, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 5
    CAS: 220792-57-4 Formula: C19H26ClN7O Molecular Weight: 403.91
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: A274969
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    IUPAC Name
    (2R)-2-[[6-(3-amino-5-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol
    SMILES
    CC(C)C(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=CC(=C3)N)Cl
    InChIKey
    RAMROQQYRRQPDL-HNNXBMFYSA-N
    InChI
    1S/C19H26ClN7O/c1-10(2)15(8-28)24-19-25-17(23-14-6-12(20)5-13(21)7-14)16-18(26-19)27(9-22-16)11(3)4/h5-7,9-11,15,28H,8,21H2,1-4H3,(H2,23,24,25,26)/t15show more
    Synonyms
    2-{[6-(3-Amino-5-chloroanilino)-9-(propan-2-yl)-1,9-dihydro-2H-purin-2-ylidene]amino}-3-methylbutan-1-ol | NCGC000253...
  7. Amantadine hydrochloride, Matrix protein 2 inhibitor
    CAS: 665-66-7 EC Number: 211-560-2 Formula: C10H17N·HCl Molecular Weight: 187.71
    Solid ≥99%(T)
    ● In Stock — US warehouse, ships to EU* Item #: A109736
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    IUPAC Name
    adamantan-1-amine;hydrochloride
    SMILES
    C1C2CC3CC1CC(C2)(C3)N.Cl
    InChIKey
    WOLHOYHSEKDWQH-UHFFFAOYSA-N
    InChI
    1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H,1-6,11H2;1H
    Synonyms
    AKOS015951188 | AMANTADINE HYDROCHLORIDE [MART.] | s2451 | Tricyclo(3.3.1.13,7)decan-1-amine, hydrochloride | AMANTAD...
  8. Dendrobine
    CAS: 2115-91-5 Formula: C16H25NO2 Molecular Weight: 263.37
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: D302777
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    IUPAC Name
    (1S,4S,7S,8R,11R,12R,13S)-2,12-dimethyl-13-propan-2-yl-10-oxa-2-azatetracyclo[5.4.1.18,11.04,12]tridecan-9-one
    SMILES
    CC(C)C1C2C3CCC4C3(C(C1OC2=O)N(C4)C)C
    InChIKey
    RYAHJFGVOCZDEI-UFFNCVEVSA-N
    InChI
    1S/C16H25NO2/c1-8(2)11-12-10-6-5-9-7-17(4)14(16(9,10)3)13(11)19-15(12)18/h8-14H,5-7H2,1-4H3/t9-,10+,11+,12-,13-,14-,16+/m1/s1
    Synonyms
    HY-N0638 | CHEBI:4400 | AC-34706 | (1S,4S,7S,8R,11R,12R,13S)-2,12-Dimethyl-13-propan-2-yl-10-oxa-2-azatetracyclo[5.4....
  9. Dinaciclib (SCH727965), Cyclin-dependent kinase 9 inhibitor
    CAS: 779353-01-4 EC Number: 814-152-8 Formula: C21H28N6O2 Molecular Weight: 396.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: D127362
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    IUPAC Name
    2-[(2S)-1-[3-ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol
    SMILES
    CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCCC4CCO
    InChIKey
    PIMQWRZWLQKKBJ-SFHVURJKSA-N
    InChI
    1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,show more
    Synonyms
    1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2S-piperidineethanol | NSC800091 | NS...
  10. Tyrphostin AG 494
    CAS: 133550-35-3 EC Number: 810-936-9 PubChem CID: 5328771 Formula: C16H12N2O3 Molecular Weight: 280.28
    ● In Stock — US warehouse, ships to EU* Item #: T162509
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    IUPAC Name
    (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide
    SMILES
    C1=CC=C(C=C1)NC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
    InChIKey
    HKHOVJYOELRGMV-XYOKQWHBSA-N
    InChI
    1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)/b12-8+
    Synonyms
    MKXZASYAUGDDCJ-UHFFFAOYSA-N | DTXSID201018515 | HMS3414I07 | s6509 | AKOS024458583 | HMS2232N04 | NCGC00024687-02 | B...
  11. 7BIO
    CAS: 916440-85-2 PubChem CID: 135423792 Formula: C16H10BrN3O2 Molecular Weight: 356.17
    ● In Stock — US warehouse, ships to EU* Item #: B338496
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    IUPAC Name
    7-bromo-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol
    SMILES
    C1=CC=C2C(=C1)C(=C(N2)C3=C(NC4=C3C=CC=C4Br)O)N=O
    InChIKey
    HYMACPDEJIEMST-UHFFFAOYSA-N
    InChI
    1S/C16H10BrN3O2/c17-10-6-3-5-9-12(16(21)19-13(9)10)15-14(20-22)8-4-1-2-7-11(8)18-15/h1-7,18-19,21H
    Synonyms
    7-Bromoindirubin-3'-oxime | 7-bromo-3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
  12. 1-(2-Thiazolylazo)-2-naphthol
    CAS: 1147-56-4 EC Number: 214-555-3 PubChem CID: 93572 Formula: C13H9N3OS Molecular Weight: 255.3
    ● In Stock — US warehouse, ships to EU* Item #: T162491
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    IUPAC Name
    1-(1,3-thiazol-2-yldiazenyl)naphthalen-2-ol
    SMILES
    C1=CC=C2C(=C1)C=CC(=C2N=NC3=NC=CS3)O
    InChIKey
    IOMXCGDXEUDZAK-UHFFFAOYSA-N
    InChI
    1S/C13H9N3OS/c17-11-6-5-9-3-1-2-4-10(9)12(11)15-16-13-14-7-8-18-13/h1-8,17H
    Synonyms
    GCBAKGGJQPMJLL-NTCAYCPXSA- | 2-Naphthalenol,1-[2-(2-thiazolyl)diazenyl]- | Acide bromebrique | (1Z)-1-(2-thiazolylhyd...
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Frequently Asked Questions

What can I find under CDK?
This listing collects compounds associated with CDK within our Cell Cycle/DNA Damage area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for CDK?
Consider the reported potency of each CDK compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for CDK compounds?
Each CDK product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search CDK compounds by activity or structure?
Yes. Filter the CDK listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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