CDK

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  1. LDC 000067
    CAS: 1073485-20-7 EC Number: 860-308-3 Formula: C18H18N4O3S Molecular Weight: 370.43
    ● In Stock — US warehouse, ships to EU* Item #: L288036
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    IUPAC Name
    [3-[[6-(2-methoxyphenyl)pyrimidin-4-yl]amino]phenyl]methanesulfonamide
    SMILES
    COC1=CC=CC=C1C2=CC(=NC=N2)NC3=CC=CC(=C3)CS(=O)(=O)N
    InChIKey
    GGQCIOOSELPMBB-UHFFFAOYSA-N
    InChI
    1S/C18H18N4O3S/c1-25-17-8-3-2-7-15(17)16-10-18(21-12-20-16)22-14-6-4-5-13(9-14)11-26(19,23)24/h2-10,12H,11H2,1H3,(H2,19,23,24)(H,20,21,22)
    Synonyms
    BDBM50013510 | BCP10866 | 3-(2-(Dimethylamino)ethyl)-N-methylindole-5-methanesulfonamide | MFCD28137788 | 3-[[6-(2-Me...
  2. LEE011 succinate, Cyclin-dependent kinase 6 inhibitor
    CAS: 1374639-75-4 Formula: C27H36N8O5 Molecular Weight: 552.63
    ● In Stock — US warehouse, ships to EU* Item #: L302513
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    IUPAC Name
    butanedioic acid;7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide
    SMILES
    CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5.C(CC(=O)O)C(=O)O
    InChIKey
    NHANOMFABJQAAH-UHFFFAOYSA-N
    InChI
    1S/C23H30N8O.C4H6O4/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30;5-3(6)1-2-4(7)8/h7-8,13-15,show more
    Synonyms
    D10979 | Q27274660 | SB18482 | 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]...
  3. NVP-LCQ195
    CAS: 902156-99-4 Formula: C17H19Cl2N5O4S Molecular Weight: 460.33
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: N127100
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    IUPAC Name
    4-[(2,6-dichlorobenzoyl)amino]-N-(1-methylsulfonylpiperidin-4-yl)-1H-pyrazole-5-carboxamide
    SMILES
    CS(=O)(=O)N1CCC(CC1)NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl
    InChIKey
    CCUXEBOOTMDSAM-UHFFFAOYSA-N
    InChI
    1S/C17H19Cl2N5O4S/c1-29(27,28)24-7-5-10(6-8-24)21-17(26)15-13(9-20-23-15)22-16(25)14-11(18)3-2-4-12(14)19/h2-4,9-10H,5-8H2,1H3,(H,20,23)(H,21,26)(H,22show more
    Synonyms
    4-(2,6-dichlorobenzamido)-N-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazole-3-carboxamide | AT9311 | AT-9311 | CLB1569...
  4. SB1317, Tyrosine-protein kinase JAK2 inhibitor
    CAS: 937270-47-8 PubChem CID: 16739650 Formula: C23H24N4O Molecular Weight: 372.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S127924
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    IUPAC Name
    (16E)-14-methyl-20-oxa-5,7,14,27-tetrazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8,10,12(26),16,21,23-decaene
    SMILES
    CN1CC=CCCOC2=CC=CC(=C2)C3=NC(=NC=C3)NC4=CC=CC(=C4)C1
    InChIKey
    VXBAJLGYBMTJCY-NSCUHMNNSA-N
    InChI
    1S/C23H24N4O/c1-27-13-3-2-4-14-28-21-10-6-8-19(16-21)22-11-12-24-23(26-22)25-20-9-5-7-18(15-20)17-27/h2-3,5-12,15-16H,4,13-14,17H2,1H3,(H,24,25,26)/b3show more
    Synonyms
    NSC762673 | NSC-762673 | EX-A7310 | 20-Oxa-5,7,14,27-tetraazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2,4,6(27),8...
  5. (R)-CR8 trihydrochloride
    CAS: 1786438-30-9 PubChem CID: 90488866 Formula: C24H32Cl3N7O Molecular Weight: 540.92
    ● In Stock — US warehouse, ships to EU* Item #: R287772
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    IUPAC Name
    (2R)-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]butan-1-ol;trihydrochloride
    SMILES
    CCC(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=C(C=C3)C4=CC=CC=N4.Cl.Cl.Cl
    InChIKey
    ORYSYXHQFOWNDK-RGFWRHHQSA-N
    InChI
    1S/C24H29N7O.3ClH/c1-4-19(14-32)28-24-29-22(21-23(30-24)31(15-27-21)16(2)3)26-13-17-8-10-18(11-9-17)20-7-5-6-12-25-20;;;/h5-12,15-16,19,32H,4,13-14H2,show more
    Synonyms
    (2R)-2-[[9-(Methylethyl)-6-[[[4-(2-pyridinyl)phenyl]methyl]amino]-9H-purin-2-yl]amino]-1-butanol trihydrochloride
  6. 1-Adamantylamine, Channel blocker of GluN2A;Channel blocker of GluN2B;Channel blocker of GluN2C;Channel blocker of GluN2D
    CAS: 768-94-5 EC Number: 212-201-2 Formula: C10H17N Molecular Weight: 151.25
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A136871
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    IUPAC Name
    adamantan-1-amine
    SMILES
    C1C2CC3CC1CC(C2)(C3)N
    InChIKey
    DKNWSYNQZKUICI-UHFFFAOYSA-N
    InChI
    1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
    Synonyms
    Symadine | 1-Adamantamine | Pk-merz | adamantan-1-amine | Adamantanamine | amantadine | Amantidine | Adamantamine | A...
  7. NVP 2, Inhibitor of cyclin dependent kinase 9
    CAS: 1263373-43-8 Formula: C27H37ClN6O2 Molecular Weight: 513.07
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: N287647
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    IUPAC Name
    4-[[[6-[5-chloro-2-[[4-[[(2R)-1-methoxypropan-2-yl]amino]cyclohexyl]amino]pyridin-4-yl]pyridin-2-yl]amino]methyl]oxane-4-carbonitrile
    SMILES
    CC(COC)NC1CCC(CC1)NC2=NC=C(C(=C2)C3=NC(=CC=C3)NCC4(CCOCC4)C#N)Cl
    InChIKey
    XWQVQSXLXAXOPJ-QNGMFEMESA-N
    InChI
    1S/C27H37ClN6O2/c1-19(16-35-2)32-20-6-8-21(9-7-20)33-26-14-22(23(28)15-30-26)24-4-3-5-25(34-24)31-18-27(17-29)10-12-36-13-11-27/h3-5,14-15,19-21,32H,6show more
    Synonyms
    4-[[[5'-Chloro-2'-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino][2,4'-bipyridin]-6-yl]amino]methyl]...
  8. (R)-DRF053 dihydrochloride
    CAS: 1241675-76-2 PubChem CID: 71433624 Formula: C23H27N7O.2HCl Molecular Weight: 490.43
    ◐ .Made to order · 8–12 wks Item #: D275076
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    IUPAC Name
    (2R)-2-[[9-propan-2-yl-6-(3-pyridin-2-ylanilino)purin-2-yl]amino]butan-1-ol;dihydrochloride
    SMILES
    CCC(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC=CC(=C3)C4=CC=CC=N4.Cl.Cl
    InChIKey
    BQPRBNGSDBTKAK-ZEECNFPPSA-N
    InChI
    1S/C23H27N7O.2ClH/c1-4-17(13-31)27-23-28-21(20-22(29-23)30(14-25-20)15(2)3)26-18-9-7-8-16(12-18)19-10-5-6-11-24-19;;/h5-12,14-15,17,31H,4,13H2,1-3H3,(show more
    Synonyms
    (2R)-2-[[9-(1-Methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]-9H-purin-2-yl]amino]-1-butanoldihydrochloride
  9. (S)-CR8, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 5;Inhibitor of dual specificity tyrosine phosphorylation regulated kinase 1A
    CAS: 1084893-56-0 Formula: C24H29N7O Molecular Weight: 431.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: C275643
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    IUPAC Name
    (2S)-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]butan-1-ol
    SMILES
    CCC(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=C(C=C3)C4=CC=CC=N4
    InChIKey
    HOCBJBNQIQQQGT-IBGZPJMESA-N
    InChI
    1S/C24H29N7O/c1-4-19(14-32)28-24-29-22(21-23(30-24)31(15-27-21)16(2)3)26-13-17-8-10-18(11-9-17)20-7-5-6-12-25-20/h5-12,15-16,19,32H,4,13-14H2,1-3H3,(Hshow more
    Synonyms
    (2S)-2-[[9-isopropyl-6-[[4-(2-pyridyl)phenyl]methylamino]purin-2-yl]amino]butan-1-ol | (S)-CR8 | CR8, (S)-Isomer | (2...
  10. 4',6,7-Trihydroxyisoflavone
    CAS: 17817-31-1 PubChem CID: 5284649 Formula: C15H10O5 Molecular Weight: 270.24
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: T405041
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    IUPAC Name
    6,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
    SMILES
    C1=CC(=CC=C1C2=COC3=CC(=C(C=C3C2=O)O)O)O
    InChIKey
    GYLUFQJZYAJQDI-UHFFFAOYSA-N
    InChI
    1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-14-6-13(18)12(17)5-10(14)15(11)19/h1-7,16-18H
    Synonyms
    UNII-PLM2K574GE | XD161696 | 4',6,7-trihydroxy isoflavone | XD161701 | LMPK12050102 | 4'',6,7,-trihydroxyisoflavone |...
  11. Senexin A
    CAS: 1366002-50-7 EC Number: 878-626-6 PubChem CID: 56927063 Formula: C17H14N4
    ● In Stock — US warehouse, ships to EU* Item #: S404102
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    IUPAC Name
    4-(2-phenylethylamino)quinazoline-6-carbonitrile
    SMILES
    C1=CC=C(C=C1)CCNC2=NC=NC3=C2C=C(C=C3)C#N
    InChIKey
    XBJCNHGQFJFCOY-UHFFFAOYSA-N
    InChI
    1S/C17H14N4/c18-11-14-6-7-16-15(10-14)17(21-12-20-16)19-9-8-13-4-2-1-3-5-13/h1-7,10,12H,8-9H2,(H,19,20,21)
    Synonyms
    BCP25089 | AC-33659 | AKOS028113542 | SCHEMBL16172718 | 1366002-50-7 | CCG-267196 | 4-(Phenethylamino)quinazoline-6-c...
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Frequently Asked Questions

What can I find under CDK?
This listing collects compounds associated with CDK within our Cell Cycle/DNA Damage area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for CDK?
Consider the reported potency of each CDK compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for CDK compounds?
Each CDK product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search CDK compounds by activity or structure?
Yes. Filter the CDK listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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