CDK

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  1. Atuveciclib (BAY-1143572)
    CAS: 1414943-88-6 Formula: C18H18FN5O2S Molecular Weight: 387.43
    ● In Stock — US warehouse, ships to EU* Item #: A414138
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    Technical Identifiers
    IUPAC Name
    4-(4-fluoro-2-methoxyphenyl)-N-[3-[(methylsulfonimidoyl)methyl]phenyl]-1,3,5-triazin-2-amine
    SMILES
    COC1=C(C=CC(=C1)F)C2=NC(=NC=N2)NC3=CC=CC(=C3)CS(=N)(=O)C
    InChIKey
    ACWKGTGIJRCOOM-UHFFFAOYSA-N
    InChI
    1S/C18H18FN5O2S/c1-26-16-9-13(19)6-7-15(16)17-21-11-22-18(24-17)23-14-5-3-4-12(8-14)10-27(2,20)25/h3-9,11,20H,10H2,1-2H3,(H,21,22,23,24)
    Synonyms
    Atuveciclib Racemate | BAY-1143572 Racemate | BAY-1143572
  2. Atuveciclib (BAY-1143572)
    CAS: 1414943-88-6 Formula: C18H18FN5O2S Molecular Weight: 387.43
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: A421533
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    Technical Identifiers
    IUPAC Name
    4-(4-fluoro-2-methoxyphenyl)-N-[3-[(methylsulfonimidoyl)methyl]phenyl]-1,3,5-triazin-2-amine
    SMILES
    COC1=C(C=CC(=C1)F)C2=NC(=NC=N2)NC3=CC=CC(=C3)CS(=N)(=O)C
    InChIKey
    ACWKGTGIJRCOOM-UHFFFAOYSA-N
    InChI
    1S/C18H18FN5O2S/c1-26-16-9-13(19)6-7-15(16)17-21-11-22-18(24-17)23-14-5-3-4-12(8-14)10-27(2,20)25/h3-9,11,20H,10H2,1-2H3,(H,21,22,23,24)
    Synonyms
    Atuveciclib Racemate | BAY-1143572 Racemate | BAY-1143572
  3. BAY 1251152
    CAS: 1610358-56-9 Formula: C19H18F2N4O2S Molecular Weight: 404.43
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B421938
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    IUPAC Name
    5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(methylsulfonimidoyl)methyl]pyridin-2-yl]pyridin-2-amine
    SMILES
    COC1=C(C=CC(=C1)F)C2=CC(=NC=C2F)NC3=NC=CC(=C3)CS(=N)(=O)C
    InChIKey
    YZCUMZWULWOUMD-UHFFFAOYSA-N
    InChI
    1S/C19H18F2N4O2S/c1-27-17-8-13(20)3-4-14(17)15-9-19(24-10-16(15)21)25-18-7-12(5-6-23-18)11-28(2,22)26/h3-10,22H,11H2,1-2H3,(H,23,24,25)
    Synonyms
    (+)-BAY-1251152 | BR164331 | (-)-5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(S-methylsulfonimidoyl)methyl]-2-pyridin...
  4. BAY 1251152
    CAS: 1610358-56-9 Formula: C19H18F2N4O2S Molecular Weight: 404.43
    ● In Stock — US warehouse, ships to EU* Item #: B414141
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    Technical Identifiers
    IUPAC Name
    5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(methylsulfonimidoyl)methyl]pyridin-2-yl]pyridin-2-amine
    SMILES
    COC1=C(C=CC(=C1)F)C2=CC(=NC=C2F)NC3=NC=CC(=C3)CS(=N)(=O)C
    InChIKey
    YZCUMZWULWOUMD-UHFFFAOYSA-N
    InChI
    1S/C19H18F2N4O2S/c1-27-17-8-13(20)3-4-14(17)15-9-19(24-10-16(15)21)25-18-7-12(5-6-23-18)11-28(2,22)26/h3-10,22H,11H2,1-2H3,(H,23,24,25)
    Synonyms
    (+)-BAY-1251152 | BR164331 | (-)-5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(S-methylsulfonimidoyl)methyl]-2-pyridin...
  5. BI-1347
    CAS: 2163056-91-3 Formula: C22H20N4O Molecular Weight: 356.42
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B422603
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    Technical Identifiers
    IUPAC Name
    2-[4-(4-isoquinolin-4-ylphenyl)pyrazol-1-yl]-N,N-dimethylacetamide
    SMILES
    CN(C)C(=O)CN1C=C(C=N1)C2=CC=C(C=C2)C3=CN=CC4=CC=CC=C43
    InChIKey
    WULUGQONDYDNKY-UHFFFAOYSA-N
    InChI
    1S/C22H20N4O/c1-25(2)22(27)15-26-14-19(12-24-26)16-7-9-17(10-8-16)21-13-23-11-18-5-3-4-6-20(18)21/h3-14H,15H2,1-2H3
    Synonyms
    1H-Pyrazole-1-acetamide,4-[4-(4-isoquinolinyl)phenyl]-N,N-dimethyl-
  6. BI-1347
    CAS: 2163056-91-3 Formula: C22H20N4O Molecular Weight: 356.42
    ● In Stock — US warehouse, ships to EU* Item #: B412682
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    Technical Identifiers
    IUPAC Name
    2-[4-(4-isoquinolin-4-ylphenyl)pyrazol-1-yl]-N,N-dimethylacetamide
    SMILES
    CN(C)C(=O)CN1C=C(C=N1)C2=CC=C(C=C2)C3=CN=CC4=CC=CC=C43
    InChIKey
    WULUGQONDYDNKY-UHFFFAOYSA-N
    InChI
    1S/C22H20N4O/c1-25(2)22(27)15-26-14-19(12-24-26)16-7-9-17(10-8-16)21-13-23-11-18-5-3-4-6-20(18)21/h3-14H,15H2,1-2H3
    Synonyms
    1H-Pyrazole-1-acetamide,4-[4-(4-isoquinolinyl)phenyl]-N,N-dimethyl-
  7. BRD 6989
    CAS: 642008-81-9 Formula: C16H16N4 Molecular Weight: 264.33
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B425253
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    Technical Identifiers
    IUPAC Name
    2-amino-6-methyl-4-pyridin-3-yl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
    SMILES
    CC1CCC2=C(C1)C(=C(C(=N2)N)C#N)C3=CN=CC=C3
    InChIKey
    QSYBDNXNOJIKML-UHFFFAOYSA-N
    InChI
    1S/C16H16N4/c1-10-4-5-14-12(7-10)15(11-3-2-6-19-9-11)13(8-17)16(18)20-14/h2-3,6,9-10H,4-5,7H2,1H3,(H2,18,20)
    Synonyms
    2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(3-pyridinyl)-3-quinolinecarbonitrile
  8. BS-194, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 5;Inhibitor of cyclin dependent kinase 7;Inhibitor of cyclin dependent kinase 9;Inhibitor of mitogen-activated protein kinase 15
    CAS: 1092443-55-4 Formula: C20H27N5O3 Molecular Weight: 385.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: B412346
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    Technical Identifiers
    IUPAC Name
    (2S,3S)-3-[[7-(benzylamino)-3-propan-2-ylpyrazolo[1,5-a]pyrimidin-5-yl]amino]butane-1,2,4-triol
    SMILES
    CC(C)C1=C2N=C(C=C(N2N=C1)NCC3=CC=CC=C3)NC(CO)C(CO)O
    InChIKey
    KRIWIRSMQRQYJG-DLBZAZTESA-N
    InChI
    1S/C20H27N5O3/c1-13(2)15-10-22-25-19(21-9-14-6-4-3-5-7-14)8-18(24-20(15)25)23-16(11-26)17(28)12-27/h3-8,10,13,16-17,21,26-28H,9,11-12H2,1-2H3,(H,23,24show more
    Synonyms
    DTXSID901109905 | GTPL8176 | compound 4k [PMID 21080703] | BCP20653 | BS194 | BS-194 | (2S,3S)-3-(7-(BENZYLAMINO)-3-I...
  9. BSJ-03-123, Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6
    CAS: 2361493-16-3 Formula: C47H56N10O11 Molecular Weight: 937.02
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: B286699
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    Technical Identifiers
    IUPAC Name
    N-[2-[2-[2-[2-[4-[6-[(6-acetyl-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazin-1-yl]ethoxy]ethoxy]ethoxy]ethyl]-2show more
    SMILES
    CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)CCOCCOCCOCCNC(=O)COC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)C8CCCC8)C(=O)C
    InChIKey
    LUHCYAOYQIFNRN-UHFFFAOYSA-N
    InChI
    1S/C47H56N10O11/c1-29-34-27-50-47(53-42(34)56(31-6-3-4-7-31)45(63)40(29)30(2)58)51-37-12-10-32(26-49-37)55-17-15-54(16-18-55)19-21-66-23-25-67-24-22-6show more
    Synonyms
    N-[2-[2-[2-[2-[4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl...
  10. BSJ-03-123, Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6
    CAS: 2361493-16-3 Formula: C47H56N10O11 Molecular Weight: 937.02
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B422770
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    Technical Identifiers
    IUPAC Name
    N-[2-[2-[2-[2-[4-[6-[(6-acetyl-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazin-1-yl]ethoxy]ethoxy]ethoxy]ethyl]-2show more
    SMILES
    CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)CCOCCOCCOCCNC(=O)COC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)C8CCCC8)C(=O)C
    InChIKey
    LUHCYAOYQIFNRN-UHFFFAOYSA-N
    InChI
    1S/C47H56N10O11/c1-29-34-27-50-47(53-42(34)56(31-6-3-4-7-31)45(63)40(29)30(2)58)51-37-12-10-32(26-49-37)55-17-15-54(16-18-55)19-21-66-23-25-67-24-22-6show more
    Synonyms
    N-[2-[2-[2-[2-[4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl...
  11. BS-181 HCl
    CAS: 1397219-81-6 Formula: C22H32N6·HCl Molecular Weight: 416.99
    ● In Stock — US warehouse, ships to EU* Item #: B412709
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    IUPAC Name
    5-N-(6-aminohexyl)-7-N-benzyl-3-propan-2-ylpyrazolo[1,5-a]pyrimidine-5,7-diamine;hydrochloride
    SMILES
    CC(C)C1=C2N=C(C=C(N2N=C1)NCC3=CC=CC=C3)NCCCCCCN.Cl
    InChIKey
    NVIJWMOQODWNFN-UHFFFAOYSA-N
    InChI
    1S/C22H32N6.ClH/c1-17(2)19-16-26-28-21(25-15-18-10-6-5-7-11-18)14-20(27-22(19)28)24-13-9-4-3-8-12-23;/h5-7,10-11,14,16-17,25H,3-4,8-9,12-13,15,23H2,1-show more
    Synonyms
    BS-181 hydrochloride | N5-(6-aminohexyl)-N7-benzyl-3-isopropylpyrazolo[1,5-a]pyrimidine-5,7-diamine hydrochloride
  12. BSJ-03-204, Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6
    CAS: 2349356-09-6 Formula: C43H48N10O8 Molecular Weight: 832.92
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ● In Stock — US warehouse, ships to EU* Item #: B287296
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    IUPAC Name
    N-[4-[4-[6-[(6-acetyl-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazin-1-yl]butyl]-2-[2-(2,6-dioxopiperidin-3-yl)-show more
    SMILES
    CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)CCCCNC(=O)COC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)C8CCCC8)C(=O)C
    InChIKey
    KDMOCOWXLQOXEB-UHFFFAOYSA-N
    InChI
    1S/C43H48N10O8/c1-25-30-23-46-43(49-38(30)52(27-8-3-4-9-27)41(59)36(25)26(2)54)47-33-14-12-28(22-45-33)51-20-18-50(19-21-51)17-6-5-16-44-35(56)24-61-3show more
    Synonyms
    N-[4-[4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piper...
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Frequently Asked Questions

What can I find under CDK?
This listing collects compounds associated with CDK within our Cell Cycle/DNA Damage area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for CDK?
Consider the reported potency of each CDK compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for CDK compounds?
Each CDK product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search CDK compounds by activity or structure?
Yes. Filter the CDK listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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