c-Fms
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117 products
Popular Products
- Ki20227, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of kinase insert domain receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of platelet derived growth factor receptor betaCAS: 623142-96-1 Formula: C24H24N4O5S Molecular Weight: 480.55Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: K425158View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[1-(1,3-thiazol-2-yl)ethyl]urea
- SMILES
- CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC
- InChIKey
- SHPFDGWALWEPGS-UHFFFAOYSA-N
- InChI
- 1S/C24H24N4O5S/c1-14(23-26-9-10-34-23)27-24(29)28-17-6-5-15(11-20(17)30-2)33-19-7-8-25-18-13-22(32-4)21(31-3)12-16(18)19/h5-14H,1-4H3,(H2,27,28,29)
- Synonyms
- 1-(4-(6,7-Dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl)-3-(1-(1,3-thiazol-2-yl)ethyl)urea | AKOS015904288 | Urea, N-(4-...
- PLX5622, Inhibitor of KIT proto-oncogene; receptor tyrosine kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: P414234View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine
- SMILES
- CC1=CC2=C(NC=C2CC3=C(N=C(C=C3)NCC4=C(N=CC(=C4)F)OC)F)N=C1
- InChIKey
- NSMOZFXKTHCPTQ-UHFFFAOYSA-N
- InChI
- 1S/C21H19F2N5O/c1-12-5-17-14(9-26-20(17)25-8-12)6-13-3-4-18(28-19(13)23)24-10-15-7-16(22)11-27-21(15)29-2/h3-5,7-9,11H,6,10H2,1-2H3,(H,24,28)(H,25,26)
- Synonyms
- 3-Pyridinemethanamine, 5-fluoro-N-(6-fluoro-5-((5-methyl-1H-pyrrolo(2,3-b)pyridin-3-yl)methyl)-2-pyridinyl)-2-methoxy...
- PRN1371, Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fibroblast growth factor receptor 2;Inhibitor of fibroblast growth factor receptor 3;Inhibitor of fibroblast growth factor receptor 4Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: P422209View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)-8-[3-(4-prop-2-enoylpiperazin-1-yl)propyl]pyrido[2,3-d]pyrimidin-7-one
- SMILES
- CNC1=NC=C2C=C(C(=O)N(C2=N1)CCCN3CCN(CC3)C(=O)C=C)C4=C(C(=CC(=C4Cl)OC)OC)Cl
- InChIKey
- PUIXMSRTTHLNKI-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- CCG-270053 | C92492 | NSC801089 | NSC-801089 | s8578 | AC-35543 | GTPL9788 | HY-101768 | EX-A2927 | PRN 1371 [WHO-DD]...
- PRN1371, Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fibroblast growth factor receptor 2;Inhibitor of fibroblast growth factor receptor 3;Inhibitor of fibroblast growth factor receptor 4Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: P414069View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)-8-[3-(4-prop-2-enoylpiperazin-1-yl)propyl]pyrido[2,3-d]pyrimidin-7-one
- SMILES
- CNC1=NC=C2C=C(C(=O)N(C2=N1)CCCN3CCN(CC3)C(=O)C=C)C4=C(C(=CC(=C4Cl)OC)OC)Cl
- InChIKey
- PUIXMSRTTHLNKI-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- CCG-270053 | C92492 | NSC801089 | NSC-801089 | s8578 | AC-35543 | GTPL9788 | HY-101768 | EX-A2927 | PRN 1371 [WHO-DD]...
- Seralutinib (GB002), Macrophage colony stimulating factor receptor inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: S419975View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-[(1S)-1-[[6-(3,4-dimethoxyphenyl)pyrazin-2-yl]amino]ethyl]phenyl]-5-methylpyridine-3-carboxamide
- SMILES
- CC1=CC(=CN=C1)C(=O)NC2=CC=CC(=C2)C(C)NC3=NC(=CN=C3)C4=CC(=C(C=C4)OC)OC
- InChIKey
- JHJNPOSPVGRIAN-SFHVURJKSA-N
- InChI
- show more
- Synonyms
- GTPL10618 | UNII-3P63ZTE3OY | SERALUTINIB [WHO-DD] | 3P63ZTE3OY | HY-109190 | AT11371 | Seralutinib | EX-A5138 | MS-2...
- cFMS Receptor Inhibitor IVCAS: 959626-45-0 Formula: C22H26N4O2 Molecular Weight: 378.47● In Stock — US warehouse, ships to EU* Item #: C333550View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-cyano-N-[2,5-di(piperidin-1-yl)phenyl]furan-2-carboxamide
- SMILES
- C1CCN(CC1)C2=CC(=C(C=C2)N3CCCCC3)NC(=O)C4=CC=C(O4)C#N
- InChIKey
- FQGXFVDABCBEFW-UHFFFAOYSA-N
- InChI
- 1S/C22H26N4O2/c23-16-18-8-10-21(28-18)22(27)24-19-15-17(25-11-3-1-4-12-25)7-9-20(19)26-13-5-2-6-14-26/h7-10,15H,1-6,11-14H2,(H,24,27)
- Synonyms
- MS-26181 | cFMS Receptor Inhibitor IV | EC-000.2370 | 5-Cyano-N-(2,5-di-1-piperidinylphenyl)-2-furancarboxamide | SCH...
- Mavrilimumab (anti-CD116), Antibody of GM-CSF receptor; α subunitCAS: 1085337-57-0Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab170528View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- CSF2RA
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human
- Isotype
- Human IgG4SP
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- CD116 antigen | CD116 | CDw116 | colony stimulating factor 2 receptor alpha subunit | colony stimulating factor 2 rec...
- JNJ-28312141, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of neurotrophic receptorCAS: 885692-52-4 PubChem CID: 11676971Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: J611261View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-cyano-N-[2-(cyclohexen-1-yl)-4-[1-[2-(dimethylamino)acetyl]piperidin-4-yl]phenyl]-1H-imidazole-2-carboxamide
- SMILES
- CN(C)CC(=O)N1CCC(CC1)C2=CC(=C(C=C2)NC(=O)C3=NC=C(N3)C#N)C4=CCCCC4
- InChIKey
- GUBJNPWVIUFSTR-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- BCP28018 | (R)-Glycerol 1-palmitate | JNJ-28312141 free base | NSC45362 | DTXSID70237129 | 4-Cyano-1H-imidazole-2-car...
- Edicotinib, Macrophage colony stimulating factor receptor inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: E610067View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-6-(2,2,6,6-tetramethyloxan-4-yl)pyridin-3-yl]-1H-imidazole-2-carboxamide
- SMILES
- CC1(CCC(=CC1)C2=C(C=CC(=N2)C3CC(OC(C3)(C)C)(C)C)NC(=O)C4=NC=C(N4)C#N)C
- InChIKey
- BNVPFDRNGHMRJS-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- JNJ-40346527 | 5-Cyano-N-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3...
- elzovantinib, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of MET proto-oncogene; receptor tyrosine kinase;Inhibitor of SRC proto-oncogene; non-receptor tyrosine kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: E610109View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CCN1CC2=C(C=CC(=C2C#N)F)OC(CNC(=O)C3=C4N=C1C=CN4N=C3N)C
- InChIKey
- UUDPUQDMSHQSKH-NSHDSACASA-N
- InChI
- show more
- Synonyms
- CSF1R-IN-2 | TPX-0022
- Cabiralizumab (anti-CSF1R), Antibody of colony stimulating factor 1 receptorCAS: 1613144-80-1Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab175484View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- CSF1R
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human
- Isotype
- Human IgG4SP
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- C FMS antibody | CD 115 antibody | CD115 antibody | CD115 antigen antibody | CFMS antibody | Colony stimulating facto...
- Emactuzumab (anti-CSF1R), Antibody of colony stimulating factor 1 receptorCAS: 1448221-67-7Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab175525View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- CSF1R
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- C FMS antibody | CD 115 antibody | CD115 antibody | CD115 antigen antibody | CFMS antibody | Colony stimulating facto...
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Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What can I find under c-Fms?
This listing collects compounds associated with c-Fms within our Protein Tyrosine Kinase/RTK area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for c-Fms?
Consider the reported potency of each c-Fms compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for c-Fms compounds?
Each c-Fms product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search c-Fms compounds by activity or structure?
Yes. Filter the c-Fms listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].