c-Fms

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  1. Pexidartinib hydrochloride, Stem cell growth factor receptor inhibitor
    CAS: 2040295-03-0 PubChem CID: 73053710 Formula: C20H16Cl2F3N5 Molecular Weight: 454.3
    ◐ .Made to order · 8–12 wks Item #: P650884
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    IUPAC Name
    5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine;hydrochloride
    SMILES
    C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F.Cl
    InChIKey
    CJLUYLRKLUYCEK-UHFFFAOYSA-N
    InChI
    1S/C20H15ClF3N5.ClH/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24;/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,2show more
    Synonyms
    AZASETRON HYDROCHLORIDE [MART.] | Pexidartinib HCl | 5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(triflu...
  2. c-Fms-IN-10
    CAS: 1527517-50-5 PubChem CID: 72943374 Formula: C22H19N7OS Molecular Weight: 429.50
    ◐ .Made to order · 8–12 wks Item #: C647227
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    IUPAC Name
    4-amino-N-[3-methyl-1-[(6-methylpyridin-2-yl)methyl]indazol-4-yl]thieno[3,2-d]pyrimidine-7-carboxamide
    SMILES
    CC1=NC(=CC=C1)CN2C3=CC=CC(=C3C(=N2)C)NC(=O)C4=CSC5=C4N=CN=C5N
    InChIKey
    KZVIZFHCMVWFNT-UHFFFAOYSA-N
    InChI
    1S/C22H19N7OS/c1-12-5-3-6-14(26-12)9-29-17-8-4-7-16(18(17)13(2)28-29)27-22(30)15-10-31-20-19(15)24-11-25-21(20)23/h3-8,10-11H,9H2,1-2H3,(H,27,30)(H2,2show more
  3. JTE-952
    CAS: 1255303-54-8 PubChem CID: 49806372 Formula: C30H34N2O6 Molecular Weight: 518.60
    ◐ .Made to order · 8–12 wks Item #: J647907
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    IUPAC Name
    [3-[4-[(4-cyclopropylphenyl)methoxy]-3-methoxyphenyl]azetidin-1-yl]-[4-[[(2S)-2,3-dihydroxypropoxy]methyl]pyridin-2-yl]methanone
    SMILES
    COC1=C(C=CC(=C1)C2CN(C2)C(=O)C3=NC=CC(=C3)COCC(CO)O)OCC4=CC=C(C=C4)C5CC5
    InChIKey
    LTTJGQBDGMNWHJ-SANMLTNESA-N
    InChI
    1S/C30H34N2O6/c1-36-29-13-24(8-9-28(29)38-18-20-2-4-22(5-3-20)23-6-7-23)25-14-32(15-25)30(35)27-12-21(10-11-31-27)17-37-19-26(34)16-33/h2-5,8-13,23,25show more
  4. c-Fms-IN-1
    CAS: 885703-64-0 PubChem CID: 11502871 Formula: C22H27N5O2 Molecular Weight: 393.48
    ◐ .Made to order · 8–12 wks Item #: C648093
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    IUPAC Name
    5-cyano-N-[4-(4-methylpiperazin-1-yl)-2-piperidin-1-ylphenyl]furan-2-carboxamide
    SMILES
    CN1CCN(CC1)C2=CC(=C(C=C2)NC(=O)C3=CC=C(O3)C#N)N4CCCCC4
    InChIKey
    UUPPIQKPNBIUKY-UHFFFAOYSA-N
    InChI
    1S/C22H27N5O2/c1-25-11-13-26(14-12-25)17-5-7-19(20(15-17)27-9-3-2-4-10-27)24-22(28)21-8-6-18(16-23)29-21/h5-8,15H,2-4,9-14H2,1H3,(H,24,28)
  5. GENZ-882706
    CAS: 2070864-35-4 PubChem CID: 126484197 Formula: C26H25N5O3 Molecular Weight: 455.51
    ◐ .Made to order · 8–12 wks Item #: G648570
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    IUPAC Name
    4-[3-[[(2S)-2-(6-methoxypyridin-3-yl)-2,3-dihydro-1,4-benzodioxin-6-yl]methyl]imidazo[4,5-b]pyridin-6-yl]-2-methylbut-3-yn-2-amine
    SMILES
    CC(C)(C#CC1=CC2=C(N=C1)N(C=N2)CC3=CC4=C(C=C3)OC(CO4)C5=CN=C(C=C5)OC)N
    InChIKey
    DRBFONOVLOXKJM-HSZRJFAPSA-N
    InChI
    1S/C26H25N5O3/c1-26(2,27)9-8-17-10-20-25(29-12-17)31(16-30-20)14-18-4-6-21-22(11-18)33-15-23(34-21)19-5-7-24(32-3)28-13-19/h4-7,10-13,16,23H,14-15,27Hshow more
  6. AZD7507
    CAS: 1041852-85-0 EC Number: 682-437-2 PubChem CID: 25001557 Formula: C23H27FN6O3 Molecular Weight: 454.50
    ◐ .Made to order · 8–12 wks Item #: A648867
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    IUPAC Name
    4-(2-fluoro-4-methylanilino)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide
    SMILES
    CC1=CC(=C(C=C1)NC2=C(N=NC3=CC(=C(C=C32)N4CCN(CC4)CCO)OC)C(=O)N)F
    InChIKey
    CPDGCAFPSYOTGO-UHFFFAOYSA-N
    InChI
    1S/C23H27FN6O3/c1-14-3-4-17(16(24)11-14)26-21-15-12-19(30-7-5-29(6-8-30)9-10-31)20(33-2)13-18(15)27-28-22(21)23(25)32/h3-4,11-13,31H,5-10H2,1-2H3,(H2,show more
    Synonyms
    AMY16926 | BDBM50492685 | A16886 | 4-(2-fluoro-4-methylanilino)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoli...
  7. Velzatinib(M4205)
    CAS: 2590556-80-0 PubChem CID: 155587867 Formula: C29H32N8O Molecular Weight: 508.62
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: M650715
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    IUPAC Name
    N-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine
    SMILES
    CN1C=C(C=N1)C2=CC=C(C=C2)CNC3=NC=NC(=C3)C4=CN=C5N4C=CC(=C5)OCCCN6CCCC6
    InChIKey
    LVMAULGVWBINFP-UHFFFAOYSA-N
    InChI
    1S/C29H32N8O/c1-35-20-24(18-34-35)23-7-5-22(6-8-23)17-30-28-16-26(32-21-33-28)27-19-31-29-15-25(9-13-37(27)29)38-14-4-12-36-10-2-3-11-36/h5-9,13,15-16show more
    Synonyms
    [4-(Methyl-1H-pyrazol-4-yl)-benzyl] -(6-[7-(3-pyrrolidin-1-yl-propoxy)-imidazo[1,2-a] pyridin-3-yl]-pyrimidin-4-yl]-a...
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under c-Fms?
This listing collects compounds associated with c-Fms within our Protein Tyrosine Kinase/RTK area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for c-Fms?
Consider the reported potency of each c-Fms compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for c-Fms compounds?
Each c-Fms product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search c-Fms compounds by activity or structure?
Yes. Filter the c-Fms listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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