COMT
Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.
39 products
Popular Products
- (-)-Gallocatechin gallate◐ .Made to order · 8–12 wks Item #: G106899View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [(2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
- SMILES
- C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
- InChIKey
- WMBWREPUVVBILR-NQIIRXRSSA-N
- InChI
- 1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21+/m1/s1
- Synonyms
- GCG | (-)-Gallocatechin 3-O-gallate | CCRIS 9286 | (-)-Gallocatechin gallate | Q27166763 | AKOS015901852 | NVP-XAA 22...
- (-)-Gallocatechin gallate10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: G423917View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [(2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
- SMILES
- C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
- InChIKey
- WMBWREPUVVBILR-NQIIRXRSSA-N
- InChI
- 1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21+/m1/s1
- Synonyms
- (-)-Gallocatechin 3-O-gallate | CCRIS 9286 | (-)-Gallocatechin gallate | Q27166763 | AKOS015901852 | NVP-XAA 225 | A8...
- Flopropione10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: F422731View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-(2,4,6-trihydroxyphenyl)propan-1-one
- SMILES
- CCC(=O)C1=C(C=C(C=C1O)O)O
- InChIKey
- PTHLEKANMPKYDB-UHFFFAOYSA-N
- InChI
- 1S/C9H10O4/c1-2-6(11)9-7(12)3-5(10)4-8(9)13/h3-4,10,12-13H,2H2,1H3
- Synonyms
- 13907 R.P. | FLOPROPIONE [INN] | propanoyl-phloroglucinol | Labrodax | 05V5NVB5Y1 | KBio2_001043 | Pharmakon1600-0150...
- Rosmarinic acidCAS: 20283-92-5 EC Number: 606-487-1 PubChem CID: 5281792 Formula: C18H16O8 Molecular Weight: 360.31Liquid 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: R422467View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxypropanoic acid
- SMILES
- OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2
- InChIKey
- DOUMFZQKYFQNTF-WUTVXBCWSA-N
- InChI
- 1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1
- Synonyms
- rosmarinic acid|20283-92-5|Rosemary acid|Labiatenic acid|Rosmarinicacid|Labiatic acid|(R)-rosmarinic acid|trans-Rosma...
- Serotonin hydrochlorideCAS: 153-98-0 EC Number: 628-480-2 PubChem CID: 160436 Formula: C10H12N2O·HCl Molecular Weight: 212.6810mM in DMSO◐ .Made to order · 8–12 wks Item #: S421830View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-(2-aminoethyl)-1H-indol-5-ol;hydrochloride
- SMILES
- C1=CC2=C(C=C1O)C(=CN2)CCN.Cl
- InChIKey
- MDIGAZPGKJFIAH-UHFFFAOYSA-N
- InChI
- 1S/C10H12N2O.ClH/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;/h1-2,5-6,12-13H,3-4,11H2;1H
- Synonyms
- 5-HT | 5-HT hydrochloride | CHEBI:181195 | SR-01000075577-1 | 5-HT HCl | 5-hydroxy tryptamine hydrochloride | A809482...
- 3-Methoxy-L-tyrosine monohydratepowder◐ .Made to order · 8–12 wks Item #: M476428View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2S)-2-amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid;hydrate
- SMILES
- COC1=C(C=CC(=C1)CC(C(=O)O)N)O.O
- InChIKey
- IDRRCKUGGXLORG-FJXQXJEOSA-N
- InChI
- 1S/C10H13NO4.H2O/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14;/h2-3,5,7,12H,4,11H2,1H3,(H,13,14);1H2/t7-;/m0./s1
- Synonyms
- 3-Methoxy Tyrosine Monohydrate | 3-Methoxy-L-tyrosine monohydrate | 3-OMD | MFCD00150495 | 3-Methoxy-L-tyrosine monoh...
- 5-Hydroxyferulic acid◐ .Made to order · 8–12 wks Item #: H649625View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-3-(3,4-dihydroxy-5-methoxyphenyl)prop-2-enoic acid
- SMILES
- COC1=CC(=CC(=C1O)O)C=CC(=O)O
- InChIKey
- YFXWTVLDSKSYLW-NSCUHMNNSA-N
- InChI
- 1S/C10H10O5/c1-15-8-5-6(2-3-9(12)13)4-7(11)10(8)14/h2-5,11,14H,1H3,(H,12,13)/b3-2+
- Synonyms
- SR-01000597542-1 | (2E)-3-(3,4-Dihydroxy-5-methoxyphenyl)-2-propenoic acid | 3-(3,4-dihydroxy-5-methoxyphenyl)acrylic...
- Nebicapone, Catechol O-methyltransferase inhibitorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Made to order · 8–12 wks Item #: N651551View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenylethanone
- SMILES
- C1=CC=C(C=C1)CC(=O)C2=CC(=C(C(=C2)O)O)[N+](=O)[O-]
- InChIKey
- MRFOLGFFTUGAEB-UHFFFAOYSA-N
- InChI
- 1S/C14H11NO5/c16-12(6-9-4-2-1-3-5-9)10-7-11(15(19)20)14(18)13(17)8-10/h1-5,7-8,17-18H,6H2
- Synonyms
- Ethanone, 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenyl- | BIA 3-202 | 1-(3,4-dihydroxy-5-nitro-phenyl)-2-phenyl-ethanone ...
- Nitecapone (OR-462)CAS: 116313-94-1 EC Number: 802-638-2 PubChem CID: 5464105 Formula: C12H11NO6 Molecular Weight: 265.22Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: N648818View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(3,4-dihydroxy-5-nitrophenyl)methylidene]pentane-2,4-dione
- SMILES
- CC(=O)C(=CC1=CC(=C(C(=C1)O)O)[N+](=O)[O-])C(=O)C
- InChIKey
- UPMRZALMHVUCIN-UHFFFAOYSA-N
- InChI
- 1S/C12H11NO6/c1-6(14)9(7(2)15)3-8-4-10(13(18)19)12(17)11(16)5-8/h3-5,16-17H,1-2H3
- Synonyms
- 98BS722498 | Nitecapona [INN-Spanish] | Nitecapone [INN] | Q7041230 | Nitecapone | Nitecaponum | 3-[(3,4-dihydroxy-5-...
- Entacapone-d10CAS: 1185241-19-3 Formula: C14H5D10N3O5 Molecular Weight: 315.35◐ .Made to order · 8–12 wks Item #: E649682View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-bis(1,1,2,2,2-pentadeuterioethyl)prop-2-enamide
- SMILES
- CCN(CC)C(=O)C(=CC1=CC(=C(C(=C1)O)O)[N+](=O)[O-])C#N
- InChIKey
- JRURYQJSLYLRLN-YFIMXNTNSA-N
- InChI
- 1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/b10-5+/i1D3,2D3,3D2,4D2
- (3,4-Dihydroxy-5-nitrophenyl)(2-fluorophenyl)methanone◐ .Made to order · 8–12 wks Item #: D1367421View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3,4-dihydroxy-5-nitrophenyl)-(2-fluorophenyl)methanone
- SMILES
- C1=CC=C(C(=C1)C(=O)C2=CC(=C(C(=C2)O)O)[N+](=O)[O-])F
- InChIKey
- RQPAUNZYTYHKHA-UHFFFAOYSA-N
- InChI
- 1S/C13H8FNO5/c14-9-4-2-1-3-8(9)12(17)7-5-10(15(19)20)13(18)11(16)6-7/h1-6,16,18H
- 3-O-Methyltolcapone-dCAS: 2469274-07-3 Formula: C15H9D4NO5 Molecular Weight: 291.29◐ .Made to order · 8–12 wks Item #: O1441649View ProductPricing & Pack Sizes
Technical Identifiers
Fast Shipping Same-day shipping on in-stock items
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the COMT listing put together?
It draws on reported COMT annotations within Neuronal Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a COMT modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the COMT entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for COMT compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For COMT work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the COMT compound I need is not listed?
Search by CAS number or SMILES first, since analogs of COMT compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.