COMT
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39 products
Popular Products
- 3-O-Methyltolcapone-dFormula: C15H6D7NO5 Molecular Weight: 294.31◐ .Made to order · 8–12 wks Item #: O1441643View ProductPricing & Pack Sizes
Technical Identifiers
- (E)-5-Hydroxyferulic acidCAS: 110642-42-7 Formula: C10H10O5 Molecular Weight: 210.19◐ .Made to order · 8–12 wks Item #: E1441645View ProductPricing & Pack Sizes
Technical Identifiers
- BIA 3-335CAS: 359783-06-5 Formula: C20H22Cl2F3N3O5 Molecular Weight: 512.31◐ .Made to order · 8–12 wks Item #: B1441642View ProductPricing & Pack Sizes
Technical Identifiers
- COMT-IN-2Formula: C13H13NO2 Molecular Weight: 215.25◐ .Made to order · 8–12 wks Item #: C1441647View ProductPricing & Pack Sizes
Technical Identifiers
- COMT-IN-1CAS: 2987884-27-3 Formula: C24H18FN3O6 Molecular Weight: 463.41◐ .Made to order · 8–12 wks Item #: C1441648View ProductPricing & Pack Sizes
Technical Identifiers
- DHMPACAS: 18684-28-1 Formula: C10H13NO5 Molecular Weight: 227.21◐ .Made to order · 8–12 wks Item #: D1422172View ProductPricing & Pack Sizes
Technical Identifiers
- S-Adenosylhomocysteine sulfoxideCAS: 29907-86-6 PubChem CID: 10092378◐ .Made to order · 8–12 wks Item #: S1441650View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfinyl]butanoic acid
- SMILES
- C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CS(=O)CCC(C(=O)O)N)O)O)N
- InChIKey
- UCALNDAYBFUTCI-AVGQJNJTSA-N
- InChI
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- Serotonin-dCAS: 58264-95-2 Formula: C10H8D4N2O Molecular Weight: 180.24◐ .Made to order · 8–12 wks Item #: S1430373View ProductPricing & Pack Sizes
Technical Identifiers
- Serotonin-dhydrochlorideCAS: 2469263-61-2 Formula: C10H9D4ClN2O Molecular Weight: 216.70◐ .Made to order · 8–12 wks Item #: S1430157View ProductPricing & Pack Sizes
Technical Identifiers
- Tolcapone-dFormula: C14H4D7NO5 Molecular Weight: 280.28◐ .Made to order · 8–12 wks Item #: T1441644View ProductPricing & Pack Sizes
Technical Identifiers
- hMAO-B/MB-COMT-IN-2CAS: 3033106-46-3 Formula: C17H18N2O3 Molecular Weight: 298.34◐ .Made to order · 8–12 wks Item #: H1441646View ProductPricing & Pack Sizes
Technical Identifiers
- hMAO-B/MB-COMT-IN-1CAS: 254974-70-4 Formula: C16H19NO3 Molecular Weight: 273.33◐ .Made to order · 8–12 wks Item #: H1441824View ProductPricing & Pack Sizes
Technical Identifiers
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Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the COMT listing put together?
It draws on reported COMT annotations within Neuronal Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a COMT modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the COMT entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for COMT compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For COMT work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the COMT compound I need is not listed?
Search by CAS number or SMILES first, since analogs of COMT compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

