CRAC Channel
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26 products
Popular Products
- YM-58483 (BTP2）, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4CAS: 223499-30-7 EC Number: 636-569-2 PubChem CID: 2455 Formula: C15H9F6N5OS Molecular Weight: 421.32Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: Y276423View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
- SMILES
- CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
- InChIKey
- XPRZIORDEVHURQ-UHFFFAOYSA-N
- InChI
- 1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)
- Synonyms
- HMS3648I22 | AS-16763 | CRAC Channel Inhibitor, BTP2 | SR-01000644222-3 | NCGC00344111-03 | AC-35791 | HMS3886H10 | I...
- MRS 1845CAS: 544478-19-5 Formula: C21H22N2O6 Molecular Weight: 398.41Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: M336287View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1-prop-2-ynyl-4H-pyridine-3,5-dicarboxylate
- SMILES
- CCOC(=O)C1=C(N(C(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)CC#C)C
- InChIKey
- BITHABUTZRAUGT-UHFFFAOYSA-N
- InChI
- 1S/C21H22N2O6/c1-6-11-22-13(3)17(20(24)28-5)19(18(14(22)4)21(25)29-7-2)15-9-8-10-16(12-15)23(26)27/h1,8-10,12,19H,7,11H2,2-5H3
- Synonyms
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-1-(2-propynyl)-3,5-pyridinedicarboxylic acid ethyl, methyl ester | 5-O-eth...
- Sodium Tanshinone IIACAS: 69659-80-9 Formula: C19H17O6S · Na Molecular Weight: 396.39Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: S107694View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- sodium;1,6,6-trimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-2-sulfonate
- SMILES
- CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)S(=O)(=O)[O-].[Na+]
- InChIKey
- AZEZEAABTDXEHR-UHFFFAOYSA-M
- InChI
- 1S/C19H18O6S.Na/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);/q;+1/p-1
- Synonyms
- Danshen-201 | Sodium tanshinone II A sulfonate | TanshinoneIIA | SULFOTANSHINONE SODIUM II-A | DTXSID00219953 | TANSH...
- SKF-96365 hydrochloride● In Stock — US warehouse, ships to EU* Item #: S302342View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole;hydrochloride
- SMILES
- COC1=CC=C(C=C1)CCCOC(CN2C=CN=C2)C3=CC=C(C=C3)OC.Cl
- InChIKey
- FWLPKVQUECFKSW-UHFFFAOYSA-N
- InChI
- 1S/C22H26N2O3.ClH/c1-25-20-9-5-18(6-10-20)4-3-15-27-22(16-24-14-13-23-17-24)19-7-11-21(26-2)12-8-19;/h5-14,17,22H,3-4,15-16H2,1-2H3;1H
- Synonyms
- S-175 | NCGC00260374-01 | CCG-268677 | 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl-1H-imidazole hydroc...
- 2-Aminoethyl diphenylborinate (2-APB), Channel blocker of TRPC1;Channel blocker of TRPC3;Channel blocker of TRPC4;Channel blocker of TRPC5;Channel blocker of TRPC6;Channel blocker of TRPC7;Channel blocker of TRPM2;Gating inhibitor of TRPM3;Activator of TRPM6;Activator of TRPM7;Channel blockerSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: A106408View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-diphenylboranyloxyethanamine
- SMILES
- B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN
- InChIKey
- BLZVCIGGICSWIG-UHFFFAOYSA-N
- InChI
- 1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2
- Synonyms
- MFCD00014823 | SB79870 | BORINIC ACID, B,B-DIPHENYL-, 2-AMINOETHYL ESTER | 2-Aminoethyl diphenylborinate | C14H16BNO ...
- 4-(3,5-Bis(trifluoromethyl)-1h-pyrazol-1-yl)phenylamineCAS: 123066-64-8 Formula: C11H7F6N3 Molecular Weight: 295.2● In Stock — US warehouse, ships to EU* Item #: B180474View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]aniline
- SMILES
- C1=CC(=CC=C1N)N2C(=CC(=N2)C(F)(F)F)C(F)(F)F
- InChIKey
- XOXBUERZFCPKDR-UHFFFAOYSA-N
- InChI
- 1S/C11H7F6N3/c12-10(13,14)8-5-9(11(15,16)17)20(19-8)7-3-1-6(18)2-4-7/h1-5H,18H2
- Synonyms
- A890856 | C11H7F6N3 | MLS000860231 | GS-4357 | 4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]aniline | Benzenamine, 4-[...
- 2-Aminoethyl diphenylborinate, Channel blocker of TRPC1;Channel blocker of TRPC3;Channel blocker of TRPC4;Channel blocker of TRPC5;Channel blocker of TRPC6;Channel blocker of TRPC7;Channel blocker of TRPM2;Gating inhibitor of TRPM3;Activator of TRPM6;Activator of TRPM7;Channel blockerMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A424505View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-diphenylboranyloxyethanamine
- SMILES
- B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN
- InChIKey
- BLZVCIGGICSWIG-UHFFFAOYSA-N
- InChI
- 1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2
- Synonyms
- MFCD00014823 | SB79870 | BORINIC ACID, B,B-DIPHENYL-, 2-AMINOETHYL ESTER | 2-Aminoethyl diphenylborinate | C14H16BNO ...
- CM 4620, Channel blocker of Orai1;Channel blocker of Orai2CAS: 1713240-67-5 Formula: C19H11ClF3N3O3 Molecular Weight: 421.76Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: C413652View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-2-fluoro-6-methylbenzamide
- SMILES
- CC1=C(C(=CC=C1)F)C(=O)NC2=NC=C(N=C2)C3=CC4=C(C=C3Cl)OC(O4)(F)F
- InChIKey
- QQMKTHUGOQDEIL-UHFFFAOYSA-N
- InChI
- 1S/C19H11ClF3N3O3/c1-9-3-2-4-12(21)17(9)18(27)26-16-8-24-13(7-25-16)10-5-14-15(6-11(10)20)29-19(22,23)28-14/h2-8H,1H3,(H,25,26,27)
- Synonyms
- BS-15636 | CM 4620 | C73294 | BDBM50575336 | SCHEMBL18038390 | 564AW1RR37 | SB18686 | AC-35758 | CM4620 | CM-4620 | N...
- RO2959 hydrochloride● In Stock — US warehouse, ships to EU* Item #: R412934View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2,6-difluoro-N-[5-[4-methyl-1-(5-methyl-1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;hydrochloride
- SMILES
- CC1=C(CN(CC1)C2=NC=C(S2)C)C3=CN=C(C=N3)NC(=O)C4=C(C=CC=C4F)F.Cl
- InChIKey
- GMLSDODALBRLPE-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- RO2959 HCl
- SKF-96365CAS: 130495-35-1 EC Number: 634-170-8 PubChem CID: 104955 Formula: C22H26N2O3·HCl Molecular Weight: 402.9210mM in DMSO● In Stock — US warehouse, ships to EU* Item #: S421187View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole;hydrochloride
- SMILES
- COC1=CC=C(C=C1)CCCOC(CN2C=CN=C2)C3=CC=C(C=C3)OC.Cl
- InChIKey
- FWLPKVQUECFKSW-UHFFFAOYSA-N
- InChI
- 1S/C22H26N2O3.ClH/c1-25-20-9-5-18(6-10-20)4-3-15-27-22(16-24-14-13-23-17-24)19-7-11-21(26-2)12-8-19;/h5-14,17,22H,3-4,15-16H2,1-2H3;1H
- Synonyms
- S-175 | NCGC00260374-01 | CCG-268677 | 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl-1H-imidazole hydroc...
- Sodium Tanshinone IIACAS: 69659-80-9 Formula: C19H17O6S · Na Molecular Weight: 396.3910mM in DMSO● In Stock — US warehouse, ships to EU* Item #: S425575View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- sodium;1,6,6-trimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-2-sulfonate
- SMILES
- CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)S(=O)(=O)[O-].[Na+]
- InChIKey
- AZEZEAABTDXEHR-UHFFFAOYSA-M
- InChI
- 1S/C19H18O6S.Na/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);/q;+1/p-1
- Synonyms
- 69659-80-9|sodium 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonate|TANSHINONE II...
- YM-58483 (BTP2）, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4CAS: 223499-30-7 EC Number: 636-569-2 PubChem CID: 2455 Formula: C15H9F6N5OS Molecular Weight: 421.32Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: Y422686View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
- SMILES
- CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
- InChIKey
- XPRZIORDEVHURQ-UHFFFAOYSA-N
- InChI
- 1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)
- Synonyms
- HMS3648I22 | AS-16763 | CRAC Channel Inhibitor, BTP2 | SR-01000644222-3 | NCGC00344111-03 | AC-35791 | HMS3886H10 | I...
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Frequently Asked Questions
How is the CRAC Channel listing put together?
It draws on reported CRAC Channel annotations within Membrane Transporter/Ion Channel and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CRAC Channel modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CRAC Channel entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CRAC Channel compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CRAC Channel work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CRAC Channel compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CRAC Channel compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.