Cyclophilin

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  1. Cyclosporin A-Derivative 1
    CAS: 1487360-85-9 PubChem CID: 145708298
    ◐ .Made to order · 8–12 wks Item #: C1434373
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    Technical Identifiers
    IUPAC Name
    [(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(E,2S,3R,4R)-3-acetyloxy-1-[[(2S)-1-[(2-methoxy-2-oxoethyl)-methylamino]-1-oxshow more
    SMILES
    [B-](F)(F)(F)F.CCC(C(=O)N(C)CC(=O)OC)NC(=O)C(C(C(C)CC=CC)OC(=O)C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(Cshow more
    InChIKey
    LYTLCJIIBWDVIF-IYMFIMPZSA-O
    InChI
    1S/C65H117N11O14.BF4/c1-27-29-30-42(15)55(90-45(18)77)54(59(82)69-46(28-2)61(84)71(20)35-51(78)89-26)76(25)65(88)53(41(13)14)75(24)63(86)50(34-39(9)10show more
  2. Cyclosporin A-Derivative 1 Free base
    CAS: 286852-20-8 PubChem CID: 88979347 Formula: C65H117N11O14 Molecular Weight: 1276.69
    ◐ .Made to order · 8–12 wks Item #: C1434407
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    Technical Identifiers
    IUPAC Name
    methyl 2-[[(2S)-2-[[(E,2S,3R,4R)-3-acetyloxy-4-methyl-2-[methyl-[(2S)-3-methyl-2-[methyl-[(2S)-4-methyl-2-[methyl-[(2S)-4-methyl-2-[methyl-[(2R)-2-[[(show more
    SMILES
    CCC(C(=O)N(C)CC(=O)OC)NC(=O)C(C(C(C)CC=CC)OC(=O)C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)show more
    InChIKey
    PSOOLRRRIPXEQE-VFELDGILSA-N
    InChI
    1S/C65H117N11O14/c1-27-29-30-42(15)55(90-45(18)77)54(59(82)69-46(28-2)61(84)71(20)35-51(78)89-26)76(25)65(88)53(41(13)14)75(24)63(86)50(34-39(9)10)74(show more
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the Cyclophilin listing put together?
It draws on reported Cyclophilin annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Cyclophilin modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Cyclophilin entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Cyclophilin compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Cyclophilin work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Cyclophilin compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Cyclophilin compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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