DYRK

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  1. T025
    CAS: 2407433-00-3 PubChem CID: 133082038 Formula: C21H18N8 Molecular Weight: 382.42
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: T650061
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    IUPAC Name
    2-N-methyl-4-N-(pyrimidin-2-ylmethyl)-5-quinolin-6-yl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
    SMILES
    CNC1=NC2=C(C(=CN2)C3=CC4=C(C=C3)N=CC=C4)C(=N1)NCC5=NC=CC=N5
    InChIKey
    PMWVYONICYRLNY-UHFFFAOYSA-N
    InChI
    1S/C21H18N8/c1-22-21-28-19-18(20(29-21)27-12-17-24-8-3-9-25-17)15(11-26-19)13-5-6-16-14(10-13)4-2-7-23-16/h2-11H,12H2,1H3,(H3,22,26,27,28,29)
  2. Protein kinase inhibitors 1
    CAS: 1365986-44-2 PubChem CID: 132274054 Formula: C18H17N5O3S Molecular Weight: 383.4
    ◐ .Made to order · 8–12 wks Item #: P1295985
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    IUPAC Name
    (5E)-5-[[6-oxo-5-(6-piperazin-1-ylpyridin-3-yl)-1H-pyridin-3-yl]methylidene]-1,3-thiazolidine-2,4-dione
    SMILES
    C1CN(CCN1)C2=NC=C(C=C2)C3=CC(=CNC3=O)C=C4C(=O)NC(=O)S4
    InChIKey
    YHUKWWWCNSTFHL-RIYZIHGNSA-N
    InChI
    1S/C18H17N5O3S/c24-16-13(7-11(9-21-16)8-14-17(25)22-18(26)27-14)12-1-2-15(20-10-12)23-5-3-19-4-6-23/h1-2,7-10,19H,3-6H2,(H,21,24)(H,22,25,26)/b14-8+
  3. 4-(Trifluoromethyl)aniline-d
    CAS: 1219795-48-8 PubChem CID: 131668225
    ◐ .Made to order · 8–12 wks Item #: T1452263
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    IUPAC Name
    2,3,5,6-tetradeuterio-4-(trifluoromethyl)aniline
    SMILES
    C1=CC(=CC=C1C(F)(F)F)N
    InChIKey
    ODGIMMLDVSWADK-RHQRLBAQSA-N
    InChI
    1S/C7H6F3N/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4H,11H2/i1D,2D,3D,4D
  4. AnnH31
    CAS: 241809-12-1 PubChem CID: 9881447
    ◐ .Made to order · 8–12 wks Item #: A1446516
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    IUPAC Name
    2-(7-methoxy-1-methylpyrido[3,4-b]indol-9-yl)acetonitrile
    SMILES
    CC1=NC=CC2=C1N(C3=C2C=CC(=C3)OC)CC#N
    InChIKey
    FCFDJQKAPLIDTQ-UHFFFAOYSA-N
    InChI
    1S/C15H13N3O/c1-10-15-13(5-7-17-10)12-4-3-11(19-2)9-14(12)18(15)8-6-16/h3-5,7,9H,8H2,1-2H3
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the DYRK listing put together?
It draws on reported DYRK annotations within Protein Tyrosine Kinase/RTK and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a DYRK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the DYRK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for DYRK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For DYRK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the DYRK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of DYRK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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