Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- (R)-LisofyllineCAS: 100324-81-0 Formula: C13H20N4O3 Molecular Weight: 280.32Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: R341807View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(5R)-5-hydroxyhexyl]-3,7-dimethylpurine-2,6-dione
- SMILES
- CC(CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C)O
- InChIKey
- NSMXQKNUPPXBRG-SECBINFHSA-N
- InChI
- 1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3/t9-/m1/s1
- Synonyms
- (-)-lisofylline | ProTec (TN) | 1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione | 1-[(5R)...
- SJF 1521◐ .Made to order · 8–12 wks Item #: S288730View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)COCCOCCOCCOC4=CC=C(C=C4)C5=CC6=C(C=C5)N=CN=C6NC7=CC(=C(C=C7)OCC8=CC(=CC=C8)F)Cl)O
- InChIKey
- XZNORRXEBCTXPB-KHBXAZQSSA-N
- InChI
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- Synonyms
- (2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)phenoxy)-4-oxo-...
- SJF 1528◐ .Made to order · 8–12 wks Item #: S287968View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)COCCOCCOC4=CC=C(C=C4)C5=CC6=C(C=C5)N=CN=C6NC7=CC(=C(C=C7)OCC8=CC(=CC=C8)F)Cl)O
- InChIKey
- ZSCOIFSUFMYZEZ-YSWDPXALSA-N
- InChI
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- Synonyms
- (2S,4R)-1-((S)-2-(2-(2-(2-(4-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6- yl)phenoxy)ethoxy)ethoxy...
- SU-5402CAS: 215543-92-3 Formula: C17H16N2O3 Molecular Weight: 296.32● In Stock — US warehouse, ships to EU* Item #: S276590View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
- SMILES
- CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O
- InChIKey
- JNDVEAXZWJIOKB-JYRVWZFOSA-N
- InChI
- 1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
- Synonyms
- HY-10407G | BCPP000060 | SCHEMBL177917 | SU 5402 | su5402 | SU-5402 | (Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)meth...
- all-trans-Astaxanthin● In Stock — US warehouse, ships to EU* Item #: A390859View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC1=C(C(CC(C1=O)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(C(=O)C(CC2(C)C)O)C)C)C
- InChIKey
- MQZIGYBFDRPAKN-UWFIBFSHSA-N
- InChI
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- Synonyms
- DTXSID00893777 | Natupink | UNII-8XPW32PR7I | .beta.-Carotene-4,4'-dione, 3,3'-dihydroxy-, all-trans- | BCP05821 | CH...
- 1,8-Dihydroxy-3-methylanthraquinoneSolid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: D101143View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1,8-dihydroxy-3-methylanthracene-9,10-dione
- SMILES
- CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
- InChIKey
- LQGUBLBATBMXHT-UHFFFAOYSA-N
- InChI
- 1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
- Synonyms
- Chrysophansaeure | NSC 646567 | BCP23439 | MFCD00001208 | Anthraquinone, 1,8-dihydroxy-3-methyl- | Spectrum_000792 | ...
- TX-1123◐ .Made to order · 8–12 wks Item #: T339226View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]cyclopent-4-ene-1,3-dione
- SMILES
- CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C2C(=O)C=CC2=O
- InChIKey
- VUEUMQIBGLKJJD-UHFFFAOYSA-N
- InChI
- 1S/C20H24O3/c1-19(2,3)14-10-12(9-13-16(21)7-8-17(13)22)11-15(18(14)23)20(4,5)6/h7-11,23H,1-6H3
- Synonyms
- 2-((3,5-di-tert-Butyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione
- AG-1478 (Tyrphostin AG-1478)● In Stock — US warehouse, ships to EU* Item #: A126582View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC
- InChIKey
- GFNNBHLJANVSQV-UHFFFAOYSA-N
- InChI
- 1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
- Synonyms
- AG 1478 | HY-13524 | Tyrphostin AG-1478;NSC 693255 | Bio1_001322 | EX-A1236 | Maybridge1_004001 | HMS3229O03 | Tox21_...
- RSVA 405CAS: 140405-36-3 EC Number: 167-403-2 PubChem CID: 135400298 Formula: C17H20N4O2 Molecular Weight: 312.37● In Stock — US warehouse, ships to EU* Item #: R286690View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylideneamino]pyridine-4-carboxamide
- SMILES
- CCN(CC)C1=CC(=C(C=C1)C=NNC(=O)C2=CC=NC=C2)O
- InChIKey
- GWQPCBPAOAFXSJ-XDHOZWIPSA-N
- InChI
- 1S/C17H20N4O2/c1-3-21(4-2)15-6-5-14(16(22)11-15)12-19-20-17(23)13-7-9-18-10-8-13/h5-12,22H,3-4H2,1-2H3,(H,20,23)/b19-12+
- Synonyms
- 2-[[4-(Diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid
- Neratinib (HKI-272), Receptor protein-tyrosine kinase erbB-4 inhibitorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: N126132View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
- SMILES
- CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C
- InChIKey
- JWNPDZNEKVCWMY-VQHVLOKHSA-N
- InChI
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- Synonyms
- EC 244-343-6 | N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but...
- Astaxanthin≥95%(HPLC),mixture of cis and trans● In Stock — US warehouse, ships to EU* Item #: A141428View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC1=C(C(CC(C1=O)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(C(=O)C(CC2(C)C)O)C)C)C
- InChIKey
- MQZIGYBFDRPAKN-UWFIBFSHSA-N
- InChI
- show more
- Synonyms
- DTXSID00893777 | Natupink | UNII-8XPW32PR7I | .beta.-Carotene-4,4'-dione, 3,3'-dihydroxy-, all-trans- | BCP05821 | CH...
- NifuroxazideCAS: 965-52-6 Formula: C12H9N3O5 Molecular Weight: 275.22Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: N129550View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide
- SMILES
- C1=CC(=CC=C1C(=O)NN=CC2=CC=C(O2)[N+](=O)[O-])O
- InChIKey
- YCWSUKQGVSGXJO-NTUHNPAUSA-N
- InChI
- 1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+
- Synonyms
- SCHEMBL543480 | 4-hydroxy-N'-[(5-nitrofuran-2-yl)methylidene]benzohydrazide | NIFUROXAZIDE [MART.] | PM5LI0P38J | AS-...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].