Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- SGI-1776 free base, Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of histone H3 associated protein kinase;Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene;Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: S126376View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[1,2-b]pyridazin-6-amine
- SMILES
- CN1CCC(CC1)CNC2=NN3C(=NC=C3C4=CC(=CC=C4)OC(F)(F)F)C=C2
- InChIKey
- MHXGEROHKGDZGO-UHFFFAOYSA-N
- InChI
- 1S/C20H22F3N5O/c1-27-9-7-14(8-10-27)12-24-18-5-6-19-25-13-17(28(19)26-18)15-3-2-4-16(11-15)29-20(21,22)23/h2-6,11,13-14H,7-10,12H2,1H3,(H,24,26)
- Synonyms
- N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[2,1-f]pyridazin-6-amine | Imidazo[1,2-b]pyri...
- Pimozide (R6238), Dopamine receptor antagonistCAS: 2062-78-4 EC Number: 218-171-7 PubChem CID: 16362 Formula: C28H29F2N3O Molecular Weight: 461.55Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: P275736View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one
- SMILES
- C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F
- InChIKey
- YVUQSNJEYSNKRX-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- Orap | R6238 | MLS000028410 | Pimozidum | PIMOZIDE [USP MONOGRAPH] | Prestwick0_000308 | HMS501D08 | Opiran | BSPBio_...
- Genistein, Activator of CFTR;Agonist of Estrogen receptor-β;Agonist of Estrogen-related receptor-α;Agonist of Estrogen-related receptor-β;Agonist of Estrogen-related receptor-γ;Agonist of TAS2R14;Agonist of TAS2R39;Activator of TRPC5Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G106672View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
- SMILES
- C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O
- InChIKey
- TZBJGXHYKVUXJN-UHFFFAOYSA-N
- InChI
- 1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
- Synonyms
- cid_5280961 | GTPL2826 | BRN 0263823 | DH2M523P0H | MolMap_000022 | GENISTEIN (USP-RS) | Differenol A | GENISTEIN [MI...
- GaliellalactoneCAS: 133613-71-5 Formula: C11H14O3 Molecular Weight: 194.23◐ .Made to order · 8–12 wks Item #: G276337View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (4R,7R,9S,11S)-11-hydroxy-9-methyl-3-oxatricyclo[5.3.1.04,11]undec-1(10)-en-2-one
- SMILES
- CC1CC2CCC3C2(C(=C1)C(=O)O3)O
- InChIKey
- SOIISBQQYAGDKM-QJSROADHSA-N
- InChI
- 1S/C11H14O3/c1-6-4-7-2-3-9-11(7,13)8(5-6)10(12)14-9/h5-7,9,13H,2-4H2,1H3/t6-,7+,9+,11-/m0/s1
- Synonyms
- (4S,5aR,7aR,7bS)-7b-Hydroxy-4-methyl-5,5a,6,7,7a,7b-hexahydroindeno[1,7-bc]furan-2(4H)-one
- SMI-4aCAS: 438190-29-5 EC Number: 803-742-0 PubChem CID: 1361334 Formula: C11H6F3NO2S Molecular Weight: 273.23● In Stock — US warehouse, ships to EU* Item #: T125988View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (5Z)-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione
- SMILES
- C1=CC(=CC(=C1)C(F)(F)F)C=C2C(=O)NC(=O)S2
- InChIKey
- NGJLOFCOEOHFKQ-YVMONPNESA-N
- InChI
- 1S/C11H6F3NO2S/c12-11(13,14)7-3-1-2-6(4-7)5-8-9(16)15-10(17)18-8/h1-5H,(H,15,16,17)/b8-5-
- Synonyms
- 5-(3-(Trifluoromethyl)benzylidene)thiazolidine-2,4-dione | 5-[[3-(trifluoromethyl)phenyl]methylene]-2,4-thiazolidined...
- PD153035● In Stock — US warehouse, ships to EU* Item #: P125741View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC
- InChIKey
- LSPANGZZENHZNJ-UHFFFAOYSA-N
- InChI
- 1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
- Synonyms
- BRD-K26603252-001-01-9 | EX-A1235 | NSC 669364 | AM808088 | GI 230329A | PD 153035 - CAS 153436-54-5 | s6546 | InChI=...
- PD153035 HCl● In Stock — US warehouse, ships to EU* Item #: P129384View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine;hydrochloride
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl
- InChIKey
- ZJOKWAWPAPMNIM-UHFFFAOYSA-N
- InChI
- 1S/C16H14BrN3O2.ClH/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11;/h3-9H,1-2H3,(H,18,19,20);1H
- Synonyms
- J-518170 | s1079 | N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-aminium chloride | SR-01000597835 | BS-16156 | ZM25286...
- Atractylenolide ICAS: 73069-13-3 Formula: C15H18O2 Molecular Weight: 230.3Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.● In Stock — US warehouse, ships to EU* Item #: A304497View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (4aS,8aS)-3,8a-dimethyl-5-methylidene-4a,6,7,8-tetrahydro-4H-benzo[f][1]benzofuran-2-one
- SMILES
- CC1=C2CC3C(=C)CCCC3(C=C2OC1=O)C
- InChIKey
- ZTVSGQPHMUYCRS-SWLSCSKDSA-N
- InChI
- 1S/C15H18O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h8,12H,1,4-7H2,2-3H3/t12-,15+/m0/s1
- Synonyms
- HMS3886N08 | Atractylenolide I | Atractylenolide I, >=98% (HPLC) | s8291 | (4aS,8aS)-3,8a-dimethyl-5-methylene-4a,5,6...
- NifuratelCAS: 4936-47-4 Formula: C10H11N3O5S Molecular Weight: 285.28Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: N125206View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-(methylsulfanylmethyl)-3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one
- SMILES
- CSCC1CN(C(=O)O1)N=CC2=CC=C(O2)[N+](=O)[O-]
- InChIKey
- SRQKTCXJCCHINN-NYYWCZLTSA-N
- InChI
- 1S/C10H11N3O5S/c1-19-6-8-5-12(10(14)18-8)11-4-7-2-3-9(17-7)13(15)16/h2-4,8H,5-6H2,1H3/b11-4+
- Synonyms
- NF 113 | Nifuratel (USAN) | UNII-U60U6P08SP | BRN 0842878 | Lisofylline [USAN:INN] | 3-((5-NITRO-2-FURFURYLIDENE)AMIN...
- Lapatinib ditosylate monohydrate, Epidermal growth factor receptor erbB1 inhibitorCAS: 388082-78-8 EC Number: 642-915-3 PubChem CID: 11557040 Formula: C43H44ClFN4O11S3 Molecular Weight: 943.49● In Stock — US warehouse, ships to EU* Item #: L193141View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.O
- InChIKey
- XNRVGTHNYCNCFF-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- GW 572016F | D04024 | N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2...
- Glycochenodeoxycholic acid, ABCB11CAS: 640-79-9 Formula: C26H43NO5 Molecular Weight: 449.62Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G304255View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CC(CCC(=O)NCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
- InChIKey
- GHCZAUBVMUEKKP-GYPHWSFCSA-N
- InChI
- show more
- Synonyms
- [(3alpha,7alpha-dihydroxy-24-oxo-5beta-cholan-24-yl)amino]acetic acid | 451ZNJ667Y | ST 24:1;O3;G | DTXSID301020165 |...
- ButeinSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)● In Stock — US warehouse, ships to EU* Item #: B135922View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
- SMILES
- C1=CC(=C(C=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O)O
- InChIKey
- AYMYWHCQALZEGT-ORCRQEGFSA-N
- InChI
- 1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+
- Synonyms
- (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one | HSCI1_000162 | Z2312273638 | (2E)-1-(2,4-Dihydro...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].