By Signaling Pathways - JAK/STAT Signaling Supplier | High Purity

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Ochromycinone (STA-21)
CAS: 111540-00-2 Formula: C₁₉H₁₄O₄ Molecular Weight: 306.31

≥98%

● In Stock — US warehouse, ships to EU* Item #: O413885
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IUPAC Name

8-hydroxy-3-methyl-3,4-dihydro-2H-benzo[a]anthracene-1,7,12-trione

SMILES

CC1CC2=C(C(=O)C1)C3=C(C=C2)C(=O)C4=C(C3=O)C=CC=C4O

InChIKey
ZAWXOCUFQSQDJS-UHFFFAOYSA-N

InChI

1S/C19H14O4/c1-9-7-10-5-6-12-17(15(10)14(21)8-9)19(23)11-3-2-4-13(20)16(11)18(12)22/h2-6,9,20H,7-8H2,1H3

Synonyms
HY-18061 | NSC628869 | NSC-628869 | 8-hydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione | AKOS032945165 | Benz...
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Ochromycinone (STA-21)
CAS: 111540-00-2 Formula: C₁₉H₁₄O₄ Molecular Weight: 306.31

10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: O420623
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Technical Identifiers

IUPAC Name

8-hydroxy-3-methyl-3,4-dihydro-2H-benzo[a]anthracene-1,7,12-trione

SMILES

CC1CC2=C(C(=O)C1)C3=C(C=C2)C(=O)C4=C(C3=O)C=CC=C4O

InChIKey
ZAWXOCUFQSQDJS-UHFFFAOYSA-N

InChI

1S/C19H14O4/c1-9-7-10-5-6-12-17(15(10)14(21)8-9)19(23)11-3-2-4-13(20)16(11)18(12)22/h2-6,9,20H,7-8H2,1H3

Synonyms
HY-18061 | NSC628869 | NSC-628869 | 8-hydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione | AKOS032945165 | Benz...
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Oclacitinib maleate
CAS: 1640292-55-2 EC Number: 962-495-8 Formula: C₁₉H₂₇N₅O₆S Molecular Weight: 453.51

10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: O422024
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IUPAC Name

(Z)-but-2-enedioic acid;N-methyl-1-[4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl]methanesulfonamide

SMILES

CNS(=O)(=O)CC1CCC(CC1)N(C)C2=NC=NC3=C2C=CN3.C(=CC(=O)O)C(=O)O

InChIKey
VQIGDTLRBSNOBV-BTJKTKAUSA-N

InChI

1S/C15H23N5O2S.C4H4O4/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15;5-3(6)1-2-4(7)8/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19);show more

Synonyms
Oclacitinib (maleate) | BS-44681 | D10142 | N-Methyl[trans-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexyl]...
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Oclacitinib maleate
CAS: 1640292-55-2 Formula: C₁₉H₂₇N₅O₆S Molecular Weight: 453.51

≥98%

● In Stock — US warehouse, ships to EU* Item #: O413939
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Technical Identifiers

IUPAC Name

(Z)-but-2-enedioic acid;N-methyl-1-[4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl]methanesulfonamide

SMILES

CNS(=O)(=O)CC1CCC(CC1)N(C)C2=NC=NC3=C2C=CN3.C(=CC(=O)O)C(=O)O

InChIKey
VQIGDTLRBSNOBV-BTJKTKAUSA-N

InChI

1S/C15H23N5O2S.C4H4O4/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15;5-3(6)1-2-4(7)8/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19);show more

Synonyms
Oclacitinib (maleate) | BS-44681 | D10142 | N-Methyl[trans-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexyl]...
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Olafertinib (RX-518)
CAS: 1660963-42-7 Formula: C₂₉H₂₈F₂N₆O₂ Molecular Weight: 530.57

Moligand™ ? ≥98%

● In Stock — US warehouse, ships to EU* Item #: O413541
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IUPAC Name

N-[3-[2-[2,3-difluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]quinazolin-8-yl]phenyl]prop-2-enamide

SMILES

C=CC(=O)NC1=CC=CC(=C1)C2=CC=CC3=CN=C(N=C32)NC4=C(C(=C(C=C4)N5CCN(CC5)CCO)F)F

InChIKey
IDRGFNPZDVBSSE-UHFFFAOYSA-N

InChI

1S/C29H28F2N6O2/c1-2-25(39)33-21-7-3-5-19(17-21)22-8-4-6-20-18-32-29(35-28(20)22)34-23-9-10-24(27(31)26(23)30)37-13-11-36(12-14-37)15-16-38/h2-10,17-1show more

Synonyms
AKOS030632731 | olafertinib | N-[3-[2-[[2,3-difluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]amino]quinazolin-8-yl...
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Olmutinib, Epidermal growth factor receptor erbB1 inhibitor
CAS: 1353550-13-6 Formula: C₂₆H₂₆N₆O₂S Molecular Weight: 486.59

Moligand™ ? 10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: O421342
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Technical Identifiers

IUPAC Name

N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

SMILES

CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC4=C(C(=N3)OC5=CC=CC(=C5)NC(=O)C=C)SC=C4

InChIKey
FDMQDKQUTRLUBU-UHFFFAOYSA-N

InChI

1S/C26H26N6O2S/c1-3-23(33)27-19-5-4-6-21(17-19)34-25-24-22(11-16-35-24)29-26(30-25)28-18-7-9-20(10-8-18)32-14-12-31(2)13-15-32/h3-11,16-17H,1,12-15H2,show more

Synonyms
Example 1 [US20130116213] | DTXSID001319119 | FT-0615010 | SOTALOL HYDROCHLORIDE (USP-RS) | 4-{[4-({[(1R,2S)-2-Phenyl...
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PD153035
CAS: 153436-54-5 EC Number: 802-811-2 Formula: C₁₆H₁₄BrN₃O₂ Molecular Weight: 360.21

10mM in DMSO

◐ .Made to order · 8–12 wks Item #: P421820
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Technical Identifiers

IUPAC Name

N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine

SMILES

COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC

InChIKey
LSPANGZZENHZNJ-UHFFFAOYSA-N

InChI

1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)

Synonyms
BRD-K26603252-001-01-9 | EX-A1235 | NSC 669364 | AM808088 | GI 230329A | PD 153035 - CAS 153436-54-5 | s6546 | InChI=...
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PD089828
CAS: 179343-17-0 PubChem CID: 5328112 Formula: C₁₈H₁₈Cl₂N₆O Molecular Weight: 405.28

≥98%

● In Stock — US warehouse, ships to EU* Item #: P412948
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IUPAC Name

1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea

SMILES

CC(C)(C)NC(=O)NC1=C(C=C2C=NC(=NC2=N1)N)C3=C(C=CC=C3Cl)Cl

InChIKey
RRWSNCZYJCOEFX-UHFFFAOYSA-N

InChI

1S/C18H18Cl2N6O/c1-18(2,3)26-17(27)25-15-10(13-11(19)5-4-6-12(13)20)7-9-8-22-16(21)24-14(9)23-15/h4-8H,1-3H3,(H4,21,22,23,24,25,26,27)
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PF-06700841, Tyrosine-protein kinase JAK1 inhibitor
CAS: 1883299-62-4 EC Number: 973-126-5 PubChem CID: 118878093 Formula: C₁₈H₂₁F₂N₇O Molecular Weight: 389.4

Moligand™ ? ≥95%

● In Stock — US warehouse, ships to EU* Item #: P414192
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Technical Identifiers

IUPAC Name

[(1S)-2,2-difluorocyclopropyl]-[(1R,5S)-3-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone

SMILES

CN1C=C(C=N1)NC2=NC=CC(=N2)N3CC4CCC(C3)N4C(=O)C5CC5(F)F

InChIKey
BUWBRTXGQRBBHG-MJBXVCDLSA-N

InChI

1S/C18H21F2N7O/c1-25-8-11(7-22-25)23-17-21-5-4-15(24-17)26-9-12-2-3-13(10-26)27(12)16(28)14-6-18(14,19)20/h4-5,7-8,12-14H,2-3,6,9-10H2,1H3,(H,21,23,24show more

Synonyms
GTPL10459 | UNII-3X8387Q25N | Brepocitinib (USAN) | [(1S)-2,2-difluorocyclopropyl]-[(1R,5S)-3-[2-[(1-methylpyrazol-4-...
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PF-06700841, Tyrosine-protein kinase JAK1 inhibitor
CAS: 1883299-62-4 EC Number: 973-126-5 PubChem CID: 118878093 Formula: C₁₈H₂₁F₂N₇O Molecular Weight: 389.4

Moligand™ ? 10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: P422297
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Technical Identifiers

IUPAC Name

[(1S)-2,2-difluorocyclopropyl]-[(1R,5S)-3-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone

SMILES

CN1C=C(C=N1)NC2=NC=CC(=N2)N3CC4CCC(C3)N4C(=O)C5CC5(F)F

InChIKey
BUWBRTXGQRBBHG-MJBXVCDLSA-N

InChI

1S/C18H21F2N7O/c1-25-8-11(7-22-25)23-17-21-5-4-15(24-17)26-9-12-2-3-13(10-26)27(12)16(28)14-6-18(14,19)20/h4-5,7-8,12-14H,2-3,6,9-10H2,1H3,(H,21,23,24show more

Synonyms
Brepocitinib|PF-06700841 free base|PF-06700841|1883299-62-4|Brepocitinib [USAN]|3X8387Q25N|Brepocitinib (USAN)|[(1S)-...
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PF-06700841 P-Tosylate
CAS: 2140301-96-6 EC Number: 895-279-6 PubChem CID: 135087197 Formula: C₂₅H₂₉F₂N₇O₄S Molecular Weight: 561.6

◐ .Made to order · 8–12 wks Item #: P412412
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Technical Identifiers

IUPAC Name

[(1S)-2,2-difluorocyclopropyl]-[3-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone;4-methylbenzenesulfonic show more

SMILES

CC1=CC=C(C=C1)S(=O)(=O)O.CN1C=C(C=N1)NC2=NC=CC(=N2)N3CC4CCC(C3)N4C(=O)C5CC5(F)F

InChIKey
FAKGOYNHHHOTEN-WTMFEIAXSA-N

InChI

1S/C18H21F2N7O.C7H8O3S/c1-25-8-11(7-22-25)23-17-21-5-4-15(24-17)26-9-12-2-3-13(10-26)27(12)16(28)14-6-18(14,19)20;1-6-2-4-7(5-3-6)11(8,9)10/h4-5,7-8,1show more
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Pacritinib (SB1518), Tyrosine-protein kinase receptor FLT3 inhibitor
CAS: 937272-79-2 EC Number: 812-740-9 PubChem CID: 46216796 Formula: C₂₈H₃₂N₄O₃ Molecular Weight: 472.58

Moligand™ ? ≥95%

● In Stock — US warehouse, ships to EU* Item #: P413904
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Technical Identifiers

IUPAC Name

(16E)-11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaene

SMILES

C1CCN(C1)CCOC2=C3COCC=CCOCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2

InChIKey
HWXVIOGONBBTBY-ONEGZZNKSA-N

InChI

1S/C28H32N4O3/c1-2-13-32(12-1)14-17-35-27-9-8-25-19-24(27)21-34-16-4-3-15-33-20-22-6-5-7-23(18-22)26-10-11-29-28(30-25)31-26/h3-11,18-19H,1-2,12-17,20show more

Synonyms
Pacritinib (SB1518) | (16E)-11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptac...

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Frequently Asked Questions

What should I consider when selecting a JAK/STAT Signaling product?

Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.

Which JAK/STAT Signaling subcategory should I start with?

JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.

Which quality data should I check before ordering JAK/STAT Signaling?

Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

Can I search JAK/STAT Signaling by structure or CAS number?

Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

JAK/STAT signaling pages help researchers compare compounds relevant to cytokine signaling, transcriptional response, immune biology, and proliferative disease studies. Key evaluation points often include pathway node, isoform selectivity, upstream receptor context, cellular potency, biomarker response, and disease relevance. This category is useful when experiments need to connect receptor-level signaling with transcriptional outcomes across related pathway nodes. It supports both mechanism studies and discovery-stage compound selection.