🌎 Ship to: United States
Toggle Nav
Cart
Search
Same-day shipping on all in-stock items.
Advanced Search
Quick Order SDS / CoA Structure Bulk & Custom
Menu
Account
Settings
྾
224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items

JAK/STAT Signaling

Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.

Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.

1,726 products
Browse by Type Browse All Products
Shop by category

EGFR

852

Explore EGFR →

JAK

448

Explore JAK →

Pim

83

Explore Pim →

STAT

418

Explore STAT →

Popular Products

View as List Grid

Showing 409-420 of 1,726

Set Descending Direction
  1. Pyrotinib dimaleate
    Wish List Compare
    Pyrotinib dimaleate
    CAS: 1397922-61-0 PubChem CID: 72710866 Formula: C40H39ClN6O11 Molecular Weight: 815.22
    ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P414222
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (Z)-but-2-enedioic acid;(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamishow more
    SMILES
    CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CC5CCCN5C.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
    InChIKey
    KLHFGQSCVQPTIN-XUZAKNADSA-N
    InChI
    1S/C32H31ClN6O3.2C4H4O4/c1-3-41-30-17-27-25(16-28(30)38-31(40)12-10-24-8-6-14-39(24)2)32(21(18-34)19-36-27)37-22-9-11-29(26(33)15-22)42-20-23-7-4-5-13show more
    Synonyms
    (E)-N-[4-[[3-chloro-4-(2-pyridylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolyl]-3-[(2R)-1-methylpyrrolidin-2-yl]pr...
  2. Quercetagetin - ≥98% CAS No(90-18-6) by Aladdin Scientific
    Wish List Compare
    Quercetagetin
    CAS: 90-18-6 PubChem CID: 5281680 Formula: C15H10O8 Molecular Weight: 318.23
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: Q342038
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxychromen-4-one
    SMILES
    C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C(=C3O)O)O)O)O)O
    InChIKey
    ZVOLCUVKHLEPEV-UHFFFAOYSA-N
    InChI
    1S/C15H10O8/c16-6-2-1-5(3-7(6)17)15-14(22)13(21)10-9(23-15)4-8(18)11(19)12(10)20/h1-4,16-20,22H
    Synonyms
    2-(3,4-Dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4-benzopyrone | Quercetagenin | SV68G507VO | 4H-1-Benzopyran-4-one, 2-(3...
  3. RG-13022
    Wish List Compare
    RG-13022
    CAS: 136831-48-6 PubChem CID: 5353927 Formula: C16H14N2O2 Molecular Weight: 266.3
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: R421397
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (E)-3-(3,4-dimethoxyphenyl)-2-pyridin-3-ylprop-2-enenitrile
    SMILES
    COC1=C(C=C(C=C1)C=C(C#N)C2=CN=CC=C2)OC
    InChIKey
    DBGZNJVTHYFQJI-ZSOIEALJSA-N
    InChI
    1S/C16H14N2O2/c1-19-15-6-5-12(9-16(15)20-2)8-14(10-17)13-4-3-7-18-11-13/h3-9,11H,1-2H3/b14-8-
  4. RO495
    Wish List Compare
    RO495
    CAS: 1258296-60-4 PubChem CID: 57519505 Formula: C17H14Cl2N6O Molecular Weight: 389.24
    10mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: R421086
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[2-[(2-amino-6-methylpyrimidin-4-yl)amino]pyridin-4-yl]-2,6-dichlorobenzamide
    SMILES
    CC1=CC(=NC(=N1)N)NC2=NC=CC(=C2)NC(=O)C3=C(C=CC=C3Cl)Cl
    InChIKey
    LNGDQKGREFSTHB-UHFFFAOYSA-N
    InChI
    1S/C17H14Cl2N6O/c1-9-7-14(25-17(20)22-9)24-13-8-10(5-6-21-13)23-16(26)15-11(18)3-2-4-12(15)19/h2-8H,1H3,(H4,20,21,22,23,24,25,26)
  5. RO495
    Wish List Compare
    RO495
    CAS: 1258296-60-4 PubChem CID: 57519505 Formula: C17H14Cl2N6O Molecular Weight: 389.24
    ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: R412354
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[2-[(2-amino-6-methylpyrimidin-4-yl)amino]pyridin-4-yl]-2,6-dichlorobenzamide
    SMILES
    CC1=CC(=NC(=N1)N)NC2=NC=CC(=C2)NC(=O)C3=C(C=CC=C3Cl)Cl
    InChIKey
    LNGDQKGREFSTHB-UHFFFAOYSA-N
    InChI
    1S/C17H14Cl2N6O/c1-9-7-14(25-17(20)22-9)24-13-8-10(5-6-21-13)23-16(26)15-11(18)3-2-4-12(15)19/h2-8H,1H3,(H4,20,21,22,23,24,25,26)
    Synonyms
    Benzamid | N-[2-[(2-amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl]-2,6-dichloro-
  6. Ritlecitinib (PF-06651600), TEC family kinase inhibitor
    Wish List Compare
    Ritlecitinib (PF-06651600), TEC family kinase inhibitor
    CAS: 1792180-81-4 EC Number: 815-269-7 PubChem CID: 118115473 Formula: C15H19N5O Molecular Weight: 285.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: R422181
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
    SMILES
    C=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O
    InChIKey
    CBRJPFGIXUFMTM-WDEREUQCSA-N
    InChI
    1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
    Synonyms
    DB14924 | Ritlecitinib? | RITLECITINIB [WHO-DD] | PF06651600;PF 06651600 | GTPL9559 | DS-13951 | HY-100754 | AC-35550...
  7. Ritlecitinib (PF-06651600), TEC family kinase inhibitor
    Wish List Compare
    Ritlecitinib (PF-06651600), TEC family kinase inhibitor
    CAS: 1792180-81-4 EC Number: 815-269-7 PubChem CID: 118115473 Formula: C15H19N5O Molecular Weight: 285.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: R414045
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
    SMILES
    C=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O
    InChIKey
    CBRJPFGIXUFMTM-WDEREUQCSA-N
    InChI
    1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
    Synonyms
    DB14924 | RITLECITINIB [WHO-DD] | PF06651600;PF 06651600 | GTPL9559 | DS-13951 | HY-100754 | AC-35550 | PF 06651600 |...
  8. Ruxolitinib phosphate salt, Tyrosine-protein kinase JAK2 inhibitor
    Wish List Compare
    Ruxolitinib phosphate salt, Tyrosine-protein kinase JAK2 inhibitor
    CAS: 1092939-17-7 EC Number: 641-390-8 PubChem CID: 25127112 Formula: C17H21N6O4P Molecular Weight: 404.4
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: R420560
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
    SMILES
    C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
    InChIKey
    JFMWPOCYMYGEDM-XFULWGLBSA-N
    InChI
    1S/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;show more
    Synonyms
    (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrilephosphate | Jakavi (TN) | (3R)...
  9. SAR-20347 - Moligand™, ≥97% CAS No(1450881-55-6) by Aladdin Scientific
    Wish List Compare
    SAR-20347, Inhibitor of Janus kinase 1;Inhibitor of Janus kinase 2;Inhibitor of Janus kinase 3;Inhibitor of tyrosine kinase 2
    CAS: 1450881-55-6 PubChem CID: 71727668 Formula: C21H18ClFN4O4 Molecular Weight: 444.84
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: S412384
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-(2-chloro-6-fluorophenyl)-5-[4-(morpholine-4-carbonyl)anilino]-1,3-oxazole-4-carboxamide
    SMILES
    C1COCCN1C(=O)C2=CC=C(C=C2)NC3=C(N=C(O3)C4=C(C=CC=C4Cl)F)C(=O)N
    InChIKey
    HEDPDFHTQKEORT-UHFFFAOYSA-N
    InChI
    1S/C21H18ClFN4O4/c22-14-2-1-3-15(23)16(14)19-26-17(18(24)28)20(31-19)25-13-6-4-12(5-7-13)21(29)27-8-10-30-11-9-27/h1-7,25H,8-11H2,(H2,24,28)
    Synonyms
    2-(2-Chloro-6-fluorophenyl)-5-(4-(morpholine-4-carbonyl)phenylamino)oxazole-4-carboxamide | SAR20347 | SAR 20347 | 2-...
  10. SC-43 - ≥99% CAS No(1400989-25-4) by Aladdin Scientific
    Wish List Compare
    SC-43
    CAS: 1400989-25-4 EC Number: 856-649-2 PubChem CID: 70688629 Formula: C21H13ClF3N3O2 Molecular Weight: 431.8
    ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: S412391
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[3-(4-cyanophenoxy)phenyl]urea
    SMILES
    C1=CC(=CC(=C1)OC2=CC=C(C=C2)C#N)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
    InChIKey
    QIBWSQJZKMUZAK-UHFFFAOYSA-N
    InChI
    1S/C21H13ClF3N3O2/c22-19-9-6-15(11-18(19)21(23,24)25)28-20(29)27-14-2-1-3-17(10-14)30-16-7-4-13(12-26)5-8-16/h1-11H,(H2,27,28,29)
    Synonyms
    QIBWSQJZKMUZAK-UHFFFAOYSA-N | D84094 | Z2736999277 | Urea, N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(3-(4-cyanopheno...
  11. SC-1
    Wish List Compare
    SC-1
    CAS: 1313019-65-6 PubChem CID: 53327725 Formula: C21H13ClF3N3O2 Molecular Weight: 431.80
    ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S412668
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-(4-cyanophenoxy)phenyl]urea
    SMILES
    C1=CC(=CC=C1C#N)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
    InChIKey
    HVPZDXDXIQZKHU-UHFFFAOYSA-N
    InChI
    1S/C21H13ClF3N3O2/c22-19-10-5-15(11-18(19)21(23,24)25)28-20(29)27-14-3-8-17(9-4-14)30-16-6-1-13(12-26)2-7-16/h1-11H,(H2,27,28,29)
    Synonyms
    1313019-65-6 | E73479 | SCHEMBL15746582 | 3-[4-chloro-3-(trifluoromethyl)phenyl]-1-[4-(4-cyanophenoxy)phenyl]urea | 1...
  12. SC-43
    Wish List Compare
    SC-43
    CAS: 1400989-25-4 EC Number: 856-649-2 PubChem CID: 70688629 Formula: C21H13ClF3N3O2 Molecular Weight: 431.8
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: S421495
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[3-(4-cyanophenoxy)phenyl]urea
    SMILES
    C1=CC(=CC(=C1)OC2=CC=C(C=C2)C#N)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
    InChIKey
    QIBWSQJZKMUZAK-UHFFFAOYSA-N
    InChI
    1S/C21H13ClF3N3O2/c22-19-9-6-15(11-18(19)21(23,24)25)28-20(29)27-14-2-1-3-17(10-14)30-16-7-4-13(12-26)5-8-16/h1-11H,(H2,27,28,29)
    Synonyms
    QIBWSQJZKMUZAK-UHFFFAOYSA-N | D84094 | Z2736999277 | Urea, N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(3-(4-cyanopheno...
Page
per page
🚚
Fast Shipping Same-day shipping on in-stock items
📋
Technical Details Quality & specification info on every product page
📦
Pack Size Options Multiple packaging sizes with pricing access from listing
🔬
R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].
JAK/STAT signaling pages help researchers compare compounds relevant to cytokine signaling, transcriptional response, immune biology, and proliferative disease studies. Key evaluation points often include pathway node, isoform selectivity, upstream receptor context, cellular potency, biomarker response, and disease relevance. This category is useful when experiments need to connect receptor-level signaling with transcriptional outcomes across related pathway nodes. It supports both mechanism studies and discovery-stage compound selection.
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our Cookie Policy.

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.

Privacy Policy Terms of Use Cookie Policy Terms and Conditions of Sale Sales Policy
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.