Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- Gefitinib impurity 2◐ .Made to order · 8–12 wks Item #: G651932View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)benzamide
- SMILES
- COC1=C(C=C(C(=C1)N)C(=O)N)OCCCN2CCOCC2
- InChIKey
- HFUBNPPCNQAACT-UHFFFAOYSA-N
- InChI
- 1S/C15H23N3O4/c1-20-13-10-12(16)11(15(17)19)9-14(13)22-6-2-3-18-4-7-21-8-5-18/h9-10H,2-8,16H2,1H3,(H2,17,19)
- Synonyms
- Benzamide, 2-amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]- | Gefitinib impurity 2 | HY-100663 | I11734 | 2-Amino-4-me...
- DP-C-4Formula: C72H78ClF2N15O14 Molecular Weight: 1450.93◐ .Made to order · 8–12 wks Item #: D659219View ProductPricing & Pack Sizes
Technical Identifiers
- OSM-SMI-10BFormula: C21H14O7 Molecular Weight: 378.33◐ .Made to order · 8–12 wks Item #: O659424View ProductPricing & Pack Sizes
Technical Identifiers
- CMD178 TFAFormula: C9H8F5KO3Y Molecular Weight: 964.0510mM in DMSO◐ .Made to order · 8–12 wks Item #: C661623View ProductPricing & Pack Sizes
Technical Identifiers
- Almonertinib mesylate◐ .Made to order · 8–12 wks Item #: A649753View ProductPricing & Pack Sizes
Technical Identifiers
- Osimertinib-¹³C,d₃CAS: 2254100-49-5 Formula: 13CC27H30D3N7O2 Molecular Weight: 503.62Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98 atom% D,≥97 atom% 13C,≥98%◐ .Made to order · 8–12 wks Item #: O649746View ProductPricing & Pack Sizes
Technical Identifiers
- SC209CAS: 1977557-86-0 Formula: C27H44N4O4 Molecular Weight: 488.66◐ .Made to order · 8–12 wks Item #: S649992View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- OC(/C(C)=C/[C@H](C(C)C)N(C)C([C@H](C(C)(C)C)NC([C@@H](NC)C(C)(C1=CC(N)=CC=C1)C)=O)=O)=O
- BMS-599626 Hydrochloride◐ .Made to order · 8–12 wks Item #: B650380View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [(3S)-morpholin-3-yl]methyl N-[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate;hydrochloride
- SMILES
- CC1=C2C(=NC=NN2C=C1NC(=O)OCC3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F.Cl
- InChIKey
- COUSSRGSHIJMMN-FTBISJDPSA-N
- InChI
- show more
- Synonyms
- AC480 HCl | [(3S)-Morpholin-3-yl]methyl [4-({1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl}amino)-5-methylpyrrolo[2,1-f]...
- PIM-447 dihydrochloride◐ .Made to order · 8–12 wks Item #: P650758View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]pyridin-3-yl]-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide;dihydrochloride
- SMILES
- CC1CC(CC(C1)N)C2=C(C=NC=C2)NC(=O)C3=NC(=C(C=C3)F)C4=C(C=CC=C4F)F.Cl.Cl
- InChIKey
- BVRSHQQSBGCMJE-ALGQTRDQSA-N
- InChI
- show more
- PF-06459988, Epidermal growth factor receptor erbB1 inhibitor◐ .Made to order · 8–12 wks Item #: P650754View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(3R,4R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-methoxypyrrolidin-1-yl]prop-2-en-1-one
- SMILES
- CN1C=C(C=N1)NC2=NC3=C(C(=CN3)Cl)C(=N2)OCC4CN(CC4OC)C(=O)C=C
- InChIKey
- ODMXWZROLKITMS-RISCZKNCSA-N
- InChI
- show more
- Synonyms
- PF-06459988, >=98% (HPLC) | 1428774-45-1 | BDBM50159360 | PF-06459988 | 5IE92SK9EB | EX-A2705 | 1-((3R,4R)-3-(((5-Chl...
- CHZ868Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: C650952View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[2-(2,4-difluoroanilino)-1,4-dimethylbenzimidazol-5-yl]oxypyridin-2-yl]acetamide
- SMILES
- CC1=C(C=CC2=C1N=C(N2C)NC3=C(C=C(C=C3)F)F)OC4=CC(=NC=C4)NC(=O)C
- InChIKey
- KQQLBXFPTDVFAJ-UHFFFAOYSA-N
- InChI
- 1S/C22H19F2N5O2/c1-12-19(31-15-8-9-25-20(11-15)26-13(2)30)7-6-18-21(12)28-22(29(18)3)27-17-5-4-14(23)10-16(17)24/h4-11H,1-3H3,(H,27,28)(H,25,26,30)
- Synonyms
- CHZ 868 | CHZ-868 | N-(4-((2-((2,4-Difluorophenyl)amino)-1,4-dimethyl-1H-benzo[d]imidazol-5-yl)oxy)pyridin-2-yl)aceta...
- DelgocitinibCAS: 1263774-59-9 EC Number: 849-957-3 PubChem CID: 50914062 Formula: C16H18N6O Molecular Weight: 310.35Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: D651411View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(3S,4R)-3-methyl-7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile
- SMILES
- CC1CN(C12CCN(C2)C3=NC=NC4=C3C=CN4)C(=O)CC#N
- InChIKey
- LOWWYYZBZNSPDT-ZBEGNZNMSA-N
- InChI
- 1S/C16H18N6O/c1-11-8-22(13(23)2-5-17)16(11)4-7-21(9-16)15-12-3-6-18-14(12)19-10-20-15/h3,6,10-11H,2,4,7-9H2,1H3,(H,18,19,20)/t11-,16-/m0/s1
- Synonyms
- 1,6-Diazaspiro(3.4)octane-1-propanenitrile, 3-methyl-beta-oxo-6-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-, (3S,4R)- | FT-076...
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].