Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- (1S,3R,5R)-PIM447 dihydrochlorideFormula: C24H25Cl2F3N4O Molecular Weight: 513.38◐ .Made to order · 8–12 wks Item #: S659341View ProductPricing & Pack Sizes
Technical Identifiers
- HTH-01-091 TFAFormula: C28H29Cl2F3N4O4 Molecular Weight: 613.46◐ .Made to order · 8–12 wks Item #: H659342View ProductPricing & Pack Sizes
Technical Identifiers
- VVD-118313CAS: 2875046-27-6 Formula: C19H22Cl2N2O3S Molecular Weight: 429.36◐ .Made to order · 8–12 wks Item #: V650045View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- O=C(N1CCC[C@H](C1)C2=CC(Cl)=C(C=C2)Cl)C#C[C@]3(CCN(S(=O)(C)=O)C3)[H]
- BafisontamabCAS: 2437210-79-0◐ .Made to order · 8–12 wks Item #: B650069View ProductPricing & Pack Sizes
Technical Identifiers
- Tyk2-IN-7CAS: 1609391-90-3 Formula: C18H15D3N6O3S Molecular Weight: 401.46◐ .Made to order · 8–12 wks Item #: T650258View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- O=C(NC([2H])([2H])[2H])C1=NN=C(NC2=CC=CC=N2)C=C1NC3=CC=CC=C3S(=O)(C)=O
- Physalin A◐ .Made to order · 8–12 wks Item #: P650332View ProductPricing & Pack Sizes
Technical Identifiers
- SEL24-B489CAS: 1616359-00-2 EC Number: 879-181-0 PubChem CID: 76286825 Formula: C15H18Br2N4O2 Molecular Weight: 446.14◐ .Made to order · 8–12 wks Item #: S650719View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5,6-dibromo-4-nitro-2-piperidin-4-yl-1-propan-2-ylbenzimidazole
- SMILES
- CC(C)N1C2=CC(=C(C(=C2N=C1C3CCNCC3)[N+](=O)[O-])Br)Br
- InChIKey
- UOUBCIJIWDLRGM-UHFFFAOYSA-N
- InChI
- 1S/C15H18Br2N4O2/c1-8(2)20-11-7-10(16)12(17)14(21(22)23)13(11)19-15(20)9-3-5-18-6-4-9/h7-9,18H,3-6H2,1-2H3
- Synonyms
- AKOS040756928 | SEL24-B289 | UNII-9M7X64VTLI | 9M7X64VTLI | Pim/flt3 kinase inhibitor SEL24 | SEL-24 free base | 5,6-...
- FIIN-3Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Made to order · 8–12 wks Item #: F650747View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
- SMILES
- CN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(CC4=CC=C(C=C4)NC(=O)C=C)C(=O)NC5=C(C(=CC(=C5Cl)OC)OC)Cl
- InChIKey
- SFLKJNSBBVSPFE-UHFFFAOYSA-N
- InChI
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- Nazartinib S-enantiomerCAS: 1508256-20-9 Formula: C26H31ClN6O2 Molecular Weight: 495.02◐ .Made to order · 8–12 wks Item #: N650927View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- O=C(C1=CC(C)=NC=C1)NC2=NC3=CC=CC(Cl)=C3N2[C@@H]4CN(C(/C=C/CN(C)C)=O)CCCC4
- Astragaloside VI◐ .Made to order · 8–12 wks Item #: A651074View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CC1(C(CCC23C1C(CC4C2(C3)CCC5(C4(CC(C5C6(CCC(O6)C(C)(C)O)C)O)C)C)OC7C(C(C(C(O7)CO)O)O)O)OC8C(C(C(CO8)O)O)OC9C(C(C(C(O9)CO)O)O)O)C
- InChIKey
- FLPVEPQEIRRVKG-SXCMWBRFSA-N
- InChI
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- RTC-5Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: R651254View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-(trifluoromethoxy)benzenesulfonamide
- SMILES
- C1CC2=CC=CC=C2N(C3=C1C=CC(=C3)Cl)CCCNS(=O)(=O)C4=CC=C(C=C4)OC(F)(F)F
- InChIKey
- QYOJMNDDVVEPFN-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- TRC-382 | N-(3-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-4-(trifluoromethoxy)benzenesulfonamide
- LY5◐ .Made to order · 8–12 wks Item #: L651275View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5,8-dioxo-6-(pyridin-3-ylamino)naphthalene-1-sulfonamide
- SMILES
- C1=CC2=C(C(=C1)S(=O)(=O)N)C(=O)C=C(C2=O)NC3=CN=CC=C3
- InChIKey
- GSGMKINCHGAOPK-UHFFFAOYSA-N
- InChI
- 1S/C15H11N3O4S/c16-23(21,22)13-5-1-4-10-14(13)12(19)7-11(15(10)20)18-9-3-2-6-17-8-9/h1-8,18H,(H2,16,21,22)
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Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].