Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- (E/Z)-AG490CAS: 134036-52-5 Formula: C17H14N2O3 Molecular Weight: 294.30Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Made to order · 8–12 wks Item #: E1428924View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
- SMILES
- C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
- InChIKey
- TUCIOBMMDDOEMM-RIYZIHGNSA-N
- InChI
- 1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+
- Synonyms
- N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide | (E/Z)-Tyrphostin AG490 | (E/Z)-Tyrphostin B42
- (1R)-AZD-1480CAS: 935666-99-2 Formula: C14H14ClFN8 Molecular Weight: 348.77◐ .Made to order · 8–12 wks Item #: R1428819View ProductPricing & Pack Sizes
Technical Identifiers
- 8α-Tigloyloxyhirsutinolide 13-O-acetateCAS: 83182-58-5 PubChem CID: 10002209◐ .Made to order · 8–12 wks Item #: T1416868View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [(1R,2E,8S,10R,11S)-6-(acetyloxymethyl)-11-hydroxy-1,10-dimethyl-5-oxo-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-2,6-dien-8-yl] (E)-2-methylbut-2-enoate
- SMILES
- CC=C(C)C(=O)OC1CC(C2(CCC(O2)(C=C3C1=C(C(=O)O3)COC(=O)C)C)O)C
- InChIKey
- NPUVRWFJDAPMIA-BDPKFFACSA-N
- InChI
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- ABBV-712CAS: 2368945-27-9 Formula: C24H28N4O5 Molecular Weight: 452.50◐ .Made to order · 8–12 wks Item #: A1428814View ProductPricing & Pack Sizes
Technical Identifiers
- AFM24◐ .Made to order · 8–12 wks Item #: A1435522View ProductPricing & Pack Sizes
Technical Identifiers
- AJI-214CAS: 1395886-20-0 Formula: C17H13ClFN5O Molecular Weight: 357.77◐ .Made to order · 8–12 wks Item #: A1426196View ProductPricing & Pack Sizes
Technical Identifiers
- AK-1690CAS: 2984505-88-4 Formula: C51H56F2N5O11PS Molecular Weight: 1016.05◐ .Made to order · 8–12 wks Item #: A1436232View ProductPricing & Pack Sizes
Technical Identifiers
- AK-068-OHCAS: 2982851-61-4 Formula: C31H36F2N3O8PS Molecular Weight: 679.67◐ .Made to order · 8–12 wks Item #: A1435750View ProductPricing & Pack Sizes
Technical Identifiers
- AJI-100CAS: 844435-10-5 Formula: C17H14FN5O Molecular Weight: 323.32◐ .Made to order · 8–12 wks Item #: A1426176View ProductPricing & Pack Sizes
Technical Identifiers
- APT STAT3CAS: 1345420-96-3 Formula: C158H205N39O36 Molecular Weight: 3226.56◐ .Made to order · 8–12 wks Item #: A1435804View ProductPricing & Pack Sizes
Technical Identifiers
- APT STAT3, scrambledFormula: C137H190N42O43 Molecular Weight: 3113.23◐ .Made to order · 8–12 wks Item #: A1435656View ProductPricing & Pack Sizes
Technical Identifiers
- APTSTAT3-9RFormula: C223H330N80O51 Molecular Weight: 4947.51◐ .Made to order · 8–12 wks Item #: A1435854View ProductPricing & Pack Sizes
Technical Identifiers
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].