Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- (R)-AfatinibCAS: 439081-17-1 PubChem CID: 10163178◐ .Made to order · 8–12 wks Item #: R1434984View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3R)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
- SMILES
- CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
- InChIKey
- ULXXDDBFHOBEHA-QDLOVBKTSA-N
- InChI
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- (Rac)-JBJ-04-125-02 acetateFormula: C29H26FN5O3S.1/3C2H4O2 Molecular Weight: 563.63◐ .Made to order · 8–12 wks Item #: R1435652View ProductPricing & Pack Sizes
Technical Identifiers
- (Rac)-Ruxolitinib-dCAS: 2469553-67-9 Formula: C17H9D9N6 Molecular Weight: 315.42◐ .Made to order · 8–12 wks Item #: R1428542View ProductPricing & Pack Sizes
Technical Identifiers
- 2-2(t) aptamer sodium◐ .Made to order · 8–12 wks Item #: T1434697View ProductPricing & Pack Sizes
Technical Identifiers
- 2-NP◐ .Made to order · 8–12 wks Item #: N1436224View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-(1,8-naphthyridin-2-yl)phenol
- SMILES
- C1=CC=C(C(=C1)C2=NC3=C(C=CC=N3)C=C2)O
- InChIKey
- AYKMXKNVEUMLFQ-UHFFFAOYSA-N
- InChI
- 1S/C14H10N2O/c17-13-6-2-1-5-11(13)12-8-7-10-4-3-9-15-14(10)16-12/h1-9,17H
- 5-FAM-GpYLPQTV-NH2CAS: 769166-98-5 Formula: C57H68N9O19P Molecular Weight: 1214.17◐ .Made to order · 8–12 wks Item #: F1435856View ProductPricing & Pack Sizes
Technical Identifiers
- 5-FAM-GpYLPQTV-NH2 TFAFormula: C57H68N9O19P.xC2HF3O2 Molecular Weight: 1214.17 (free base)◐ .Made to order · 8–12 wks Item #: F1435857View ProductPricing & Pack Sizes
Technical Identifiers
- 5TTUFormula: C16H19N5O Molecular Weight: 297.35◐ .Made to order · 8–12 wks Item #: T1429777View ProductPricing & Pack Sizes
Technical Identifiers
- AS2553627CAS: 1251906-10-1 Formula: C18H19N5O Molecular Weight: 321.38◐ .Made to order · 8–12 wks Item #: A1428449View ProductPricing & Pack Sizes
Technical Identifiers
- AZD1208 hydrochlorideCAS: 1621866-96-3 PubChem CID: 76962885◐ .Made to order · 8–12 wks Item #: A1420266View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-phenylphenyl]methylidene]-1,3-thiazolidine-2,4-dione;hydrochloride
- SMILES
- C1CC(CN(C1)C2=C(C=CC=C2C3=CC=CC=C3)C=C4C(=O)NC(=O)S4)N.Cl
- InChIKey
- KPQHIFXAXSIKOA-SLWUYDEESA-N
- InChI
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- AZD1897CAS: 1204181-93-0 Formula: C18H23N3O3S Molecular Weight: 361.46◐ .Made to order · 8–12 wks Item #: A1436249View ProductPricing & Pack Sizes
Technical Identifiers
- AZ7550 hydrochlorideCAS: 2309762-40-9 PubChem CID: 132274051◐ .Made to order · 8–12 wks Item #: A1435468View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[methyl-[2-(methylamino)ethyl]amino]phenyl]prop-2-enamide;hydrochloride
- SMILES
- CNCCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C)OC.Cl
- InChIKey
- BHYPVGSNUFXTCM-UHFFFAOYSA-N
- InChI
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].